One-pot synthesis of 4,6-diaryl-3-cyanopyridine-2(1H)-thiones and their transformation to substituted thieno[2,3-b;4,5-b]dipyridines and pyrido[3",2":4,5]thieno[3,2-d]pyrimidines
作者:A. M. Shestopalov、K. G. Nikishin、A. V. Gromova、L. A. Rodinovskaya
DOI:10.1023/b:rucb.0000011879.89900.1f
日期:2003.10
one step by the reaction of elemental sulfur, malononitrile, and 2-aryl-1-aroylethylenes in the presence of excess triethylamine. The products were used in one-pot syntheses of substituted thieno[2,3-b;4,5-b]dipyridines and pyrido[3",2":4,5]thieno[3,2-d]pyrimidines.
摘要 4,6-二芳基-3-氰基吡啶-2(1H)-硫酮在过量三乙胺存在下,由元素硫、丙二腈和2-芳基-1-芳酰基乙烯反应一步合成。产物用于取代噻吩并[2,3-b;4,5-b]二吡啶和吡啶并[3",2":4,5]噻吩并[3,2-d]嘧啶的一锅合成。