8-sec-butyl-5,6,7,8-tetrahydroquinoline | 1352745-21-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 8-sec-butyl-5,6,7,8-tetrahydroquinoline
• 英文别名: 8-butan-2-yl-5,6,7,8-tetrahydroquinoline
• CAS: 1352745-21-1
• 化学式: C₁₃H₁₉N
• 分子量: 189.301
• InChiKey: VEUUOOHXJMZARX-UHFFFAOYSA-N

物化性质

• 沸点：
  288.8±9.0 °C(Predicted)
• 密度：
  0.955±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  12.9
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  5,6,7,8-四氢喹啉 、 2-溴丁烷 在 正丁基锂 作用下， 以 四氢呋喃 、 正己烷 为溶剂， 以89%的产率得到8-sec-butyl-5,6,7,8-tetrahydroquinoline
  参考文献：
  名称：

  Organic Compounds

  摘要：

  式子(I)的化合物，其中：n=0、1、2、3，而R=C2-C6的直链或支链烷基、烯基和环烷基取代基是有趣的香味或芳香成分，具有草本绿色的特点。

  公开号：

  US20130129655A1

文献信息

• [EN] ORGANIC COMPOUNDS<br/>[FR] COMPOSÉS ORGANIQUES
  申请人：GIVAUDAN SA

  公开号：WO2011160254A1

  公开（公告）日：2011-12-29

  Compounds of formula (I), wherein: n = 0,1,2,3, and R = C2-C6 linear and branched alkyl, alkenyl and cycloalkyl substituents are interesting flavour or fragrance ingredients having herbal-green aspects.

  公式（I）的化合物，其中：n = 0,1,2,3，R = C2-C6的线性和支链烷基，烯基和环烷基取代基，是具有草本绿色特点的有趣的香味或香料成分。
• Organic compounds
  申请人：Goeke Andreas

  公开号：US08933231B2

  公开（公告）日：2015-01-13

  Compounds of formula (I) wherein: n=0, 1, 2, 3, and R=C2-C6 linear and branched alkyl, alkenyl and cycloalkyl substituents are interesting flavor or fragrance ingredients having herbal-green aspects.

  化学式为（I）的化合物，其中：n=0，1，2，3，且R=C2-C6线性和支链烷基，烯基和环烷基取代基是有趣的香味或香料成分，具有草本绿色的特点。
• USE OF A ZINC CARBOXYLATE SALT TO IMPROVE PERFORMANCE OF A DEODORANT COMPOSITION
  申请人：Givaudan SA

  公开号：EP3998111A1

  公开（公告）日：2022-05-18

  An advantageous deodorizing composition comprising at least one zinc carboxylate salt and aluminium chlorohydrate is provided, as well as a deodorant consumer product comprising the same. Furthermore, a method of suspending aluminium chlorohydrate in an at least essentially anhydrous solvent is provided, as well as a method of preventing clumping of aluminium chlorohydrate in a deodorizing composition or a deodorant consumer product and a method of preventing clogging of a nozzle of a deodorant spray containing a deodorizing composition.

  本发明提供了一种由至少一种羧酸锌盐和氯水铝组成的有利的除臭组合物，以及由该组合物组成的除臭消费品。此外，还提供了一种将氯水铝悬浮在至少基本无水的溶剂中的方法，以及一种防止氯水铝在除臭组合物或除臭消费品中结块的方法和一种防止含有除臭组合物的除臭喷雾喷嘴堵塞的方法。
• Ferroportin inhibitors
  申请人：Vifor (International) AG

  公开号：US10364239B2

  公开（公告）日：2019-07-30

  The invention relates to novel compounds of the general formula (A-I), with Het-2 being an optionally substituted bicyclic heteroaryl of the formula (AA) pharmaceutical compositions comprising them and the use thereof as medicaments, in particular for the use as ferroportin inhibitors, more particularly for the use in the prophylaxis and/or treatment of diseases caused by a lack of hepcidin or iron metabolism disorders, such as particularly iron overload states such as in particular thalassemia and hemochromatosis.

  本发明涉及通式(A-I)的新型化合物，其中Het-2为通式(AA)的任选取代的双环杂芳基。本发明涉及由这些化合物组成的药物组合物及其作为药物的用途，特别是作为铁皮质素抑制剂的用途，尤其是用于预防和/或治疗由缺乏铁皮质素或铁代谢紊乱引起的疾病，如特别是铁过载状态，如地中海贫血症和血色病。
• Microcapsules
  申请人：Givaudan, S.A.

  公开号：US10537868B2

  公开（公告）日：2020-01-21

  Encapsulated perfume composition comprising at least one aminoplast core-shell microcapsule dispersed in a suspending medium, the microcapsule comprising a perfume-containing core encapsulated in a shell, said shell comprising a network of cross-linked aminoplast resin, wherein 75-100% of the resin comprises 50-90%, preferably from 60-85%, of a terpolymer and from 10-50%, preferably from 10-25%, of a polymeric stabilizer; the terpolymer comprising: (a) from 20-35 wt %, preferably 22-30% by weight of moieties derived from at least one triamine, (b) from 30-60 wt %, preferably 40-55% by weight of moieties derived from at least one diamine, (c) from 20-35 wt %, preferably 22-30% by weight of moieties derived from the group consisting of alkylene and alkylenoxy moieties having 1 to 6 methylene units, preferably 1 to 4 methylene units and most preferably 1 methylene unit. The encapsulated perfume composition is useful for the storage and dissemination of fragrance in various products, such as laundry products and fabric care products.

  封装香水组合物，包括至少一个分散在悬浮介质中的氨基树脂芯壳微胶囊，所述微胶囊包括封装在外壳中的含香水的芯，所述外壳包括交联氨基树脂网络，其中75-100%的树脂包括50-90%，优选60-85%的三元共聚物和10-50%，优选10-25%的聚合物稳定剂；所述三元共聚物包括： (a) 20-35%，最好是 22-30%（按重量计）由至少一种三胺衍生的分子、 (b) 30-60%（按重量计），最好是 40-55%（按重量计）衍生自至少一种二胺的分子、 (c) 20-35%，优选 22-30%（按重量计）来自具有 1 至 6 个亚甲基单元，优选 1 至 4 个亚甲基单元，最优选 1 个亚甲基单元的亚烷基和亚烷氧基分子组成的组的分子。 封装的香水组合物适用于在各种产品（如洗衣产品和织物护理产品）中储存和传播香味。