焦谷氨酸锌 | 68107-75-5

• 物质功能分类: 生物化工 - 氨基酸及其衍生物 - 谷氨酸类衍生物
• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 焦谷氨酸锌
• 中文别名: PCA锌；吡咯烷酮羧酸锌
• 英文名称: Zinc 5-oxido-3,4-dihydro-2H-pyrrole-2-carboxylate--5-hydroxy-3,4-dihydro-2H-pyrrole-2-carboxylic acid (1/1/1)
• 英文别名: zinc;5-oxido-3,4-dihydro-2H-pyrrole-2-carboxylate;5-oxopyrrolidine-2-carboxylic acid
• CAS: 68107-75-5；15454-75-8
• 化学式: C10H12N2O6Zn
• 分子量: 321.6
• InChiKey: OWVLYQRCCIEOPF-UHFFFAOYSA-L

物化性质

• 密度：
  1.617[at 20℃]
• LogP：
  1 at 25℃

计算性质

• 辛醇/水分配系数(LogP)：
  -3.97
• 重原子数：
  19
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  139
• 氢给体数：
  2
• 氢受体数：
  6

制备方法与用途

概述

焦谷氨酸系5-氧脯氨酸。它是由谷氨酸的α-NH2基和γ-羟基之间脱水形成分子内酰胺键而成；也可由谷氨酰胺分子内失去酰氨基而成。

化学性质

焦谷氨酸锌具有一定的吸湿性，遇水后容易发生潮解反应导致变质。因此，在储存时应避免与其他化学物品混放，尤其是避免与强酸或强碱接触，以防引发化学反应或危险。

用途

焦谷氨酸锌可用于制备一种含有L-焦谷氨酸的叶面肥。

生物活性

焦谷氨酸锌具有一定的抗菌活性，可用作治疗皮肤炎症时生物活性分子合成的原料。

文献信息

• Sun protection compositions comprising semi-crystalline polymers and hollow latex particles
  申请人：Candau Didier

  公开号：US20090041691A1

  公开（公告）日：2009-02-12

  Topically applicable cosmetic/dermatological UV protection compositions having enhanced SPF contain at least one organic UV screening agent and/or at least one inorganic screening agent, such compositions also containing at least the following constituents (A) and (B): A) a semi-crystalline polymer which is solid at ambient temperature and has a melting point of greater than or equal to 30° C., containing a) a polymeric backbone and b) at least one crystallizable organic side chain and/or one crystallizable organic block forming part of the backbone of this said polymer, said polymer having a number-average molecular mass Mn of greater than or equal to 1,000, and B) hollow latex particles having a particle size ranging from 150 to 380 nm, formulated into a topically applicable, physiologically acceptable medium therefor.

  具有增强SPF的适用于化妆品/皮肤科的防紫外线保护组合物至少包含一种有机紫外线过滤剂和/或至少一种无机过滤剂，此类组合物还至少包含以下成分（A）和（B）： A）半结晶聚合物，室温下为固体，熔点大于或等于30°C，包含a）聚合骨架和b）至少一种可结晶有机侧链和/或作为该聚合物骨架一部分的可结晶有机块，该聚合物具有大于或等于1,000的数均分子质量Mn，以及 B）中空乳胶颗粒，粒径范围为150至380纳米，配制成适用于局部使用的、生理上可接受的介质。
• [EN] ADHESIVE PHOTOPROTECTIVE COMPOUNDS AND USES THEREOF<br/>[FR] COMPOSÉS PHOTO-PROTECTEURS ADHÉSIFS ET LEURS UTILISATIONS
  申请人：SKINOSIVE

  公开号：WO2021123116A1

  公开（公告）日：2021-06-24

  The present invention relates to a compound represented by the following formula (I): A[B-(C)v]w, wherein A is a photoprotective moiety, B is a linker, C is a functional group, v is an integer from 1 to 2000, and w is an integer from 1 to 6. It also relates to a composition comprising the same and, more particularly, to a cosmetic or a sunscreen composition. It also relates to the use of such compounds in cosmetic and therapeutic applications. The invention also relates to the use of such compounds for reducing photodegradation and/or photoinstability of pharmaceuticals and cosmetics. The invention further relates to a material comprising a support and such a compound adhered to said support.

  本发明涉及一种由以下公式（I）表示的化合物：A[B-(C)v]w，其中A是光保护基团，B是连接基团，C是功能基团，v是从1到2000的整数，w是从1到6的整数。它还涉及包含该化合物的组合物，更具体地说，是化妆品或防晒霜组合物。还涉及在化妆品和治疗应用中使用这种化合物。该发明还涉及在药品和化妆品中减少光降解和/或光不稳定性的化合物的使用。该发明还涉及包含支撑物和该化合物粘附在该支撑物上的材料。
• Cosmetic/sunscreen compositions containing dibenzoylmethane compounds and dithiolane compound photostabilizers therefor
  申请人：Lucet-Levannier Karine

  公开号：US20100086502A1

  公开（公告）日：2010-04-08

  Cosmetic/sunscreen compositions contain a combination of at least one dibenzoylmethane sunscreen compound and a photostabilizing amount of at least one dithiolane compound of formula (I) below:

  化妆品/防晒霜组合物含有至少一种二苯甲酮类防晒剂化合物和至少一种式（I）所示的二硫杂环化合物的光稳定量。
• [EN] USE OF AT LEAST ONE HYDROXYPROPYLTRIALKYLAMMONIUM DERIVATIVE AS DEODORANT AGENT<br/>[FR] UTILISATION D'AU MOINS UN DÉRIVÉ D'HYDROXYPROPYLTRIALKYLAMMONIUM EN TANT QU'AGENT DÉODORANT
  申请人：OREAL

  公开号：WO2015091860A1

  公开（公告）日：2015-06-25

  Use of at least one hydroxypropyltrialkylammonium derivative as deodorant agent The present invention relates to the use of one or more hydroxypropyltrialkylammonium derivatives of formula (I) as defined below for treating body odour, in particular underarm odour. The invention also relates to a process for treating body odour using a composition comprising such compounds. The invention similarly relates to a composition comprising, in a physiologically acceptable medium, one or more hydroxypropyltrialkylammonium derivatives of formula (I) and one or more antiperspirant active agents and/or one or more additional deodorant active agents. The present invention also relates to one or more particular hydroxypropyltrialkylammonium-based compounds.

  至少一种羟丙基三烷基铵衍生物作为除臭剂的使用。本发明涉及使用以下所定义的一个或多个羟丙基三烷基铵衍生物（式I）来治疗体臭，特别是腋臭。该发明还涉及使用包含这些化合物的组合物来治疗体臭的方法。该发明还涉及在生理上可接受的介质中包含一个或多个羟丙基三烷基铵衍生物（式I）和一个或多个止汗活性剂和/或一个或多个额外的除臭活性剂的组合物。本发明还涉及一个或多个特定的基于羟丙基三烷基铵的化合物。
• Artificially coloring the skin with a carotene compound, a xanthophyll compound and a lipophilic green dye composition
  申请人：Cassin Guillaume

  公开号：US20100150853A1

  公开（公告）日：2010-06-17

  A method for artificially coloring the skin entails topical application thereon of a composition containing, formulated into a physiologically acceptable medium: a) at least one compound of the carotene type, b) at least one compound of the xanthophyll type, c) at least one lipophilic green dye; the composition advantageously includes a mixture of dyes including: a) at least one compound of the carotene type, b) at least astaxanthin, c) at least one lipophilic green dye.

  一种人工着色皮肤的方法包括在皮肤上局部涂抹一种含有以下成分的组合物，配制成生理可接受的介质：a) 至少一种类胡萝卜素的化合物，b) 至少一种黄色素类的化合物，c) 至少一种亲脂性绿色染料；该组合物优选包括一种混合染料，其中包括：a) 至少一种类胡萝卜素的化合物，b) 至少一种虾青素，c) 至少一种亲脂性绿色染料。