8-methoxy-4,8-dimethyl-1-(4-isopropylphenyl)-nonane | 53905-38-7

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: 8-methoxy-4,8-dimethyl-1-(4-isopropylphenyl)-nonane
• 英文别名: 1-(p-isopropylphenyl)-4,8-dimethyl-8-methoxynonane；2-methoxy-9-(p-isopropylphenyl)-2,6-dimethylnonane；Pro-drone；1-(8-methoxy-4,8-dimethylnonyl)-4-propan-2-ylbenzene
• CAS: 53905-38-7
• 化学式: C₂₁H₃₆O
• 分子量: 304.516
• InChiKey: LTNBHNLTEGZRFB-UHFFFAOYSA-N

物化性质

• 沸点：
  405.32°C (rough estimate)
• 密度：
  0.9096 (rough estimate)

计算性质

• 辛醇/水分配系数(LogP)：
  6.9
• 重原子数：
  22
• 可旋转键数：
  10
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  trans-8-methoxy-4,8-dimethyl-1-(4-isopropylphenyl)-1-nonene 以97%的产率得到
  参考文献：
  名称：

  AGUINAGA G. M.; DINIZO S. E., J. LABELLED COMPOUNDS AND RADIOPHARM., 24,(1987) N 5, 577-586

  摘要：

  DOI：

文献信息

• Process for preparation of arylterpenoid insect maturation inhibitors
  申请人：SCM Corporation

  公开号：US04484007A1

  公开（公告）日：1984-11-20

  There is provided an improved process for producing biologically active arylterpenoid compounds useful to inhibit eclosion of pupae, e.g., fly pupae or mosquito pupae. The process is characterized by reacting a terpenoid material having a terminal unsaturated linkage, e.g., dihydromyrcene (3,7-dimethylocta-1,6-diene) with a lower alkyl Grignard reagent, e.g., n-propyl magnesium chloride to form a Grignard exchange product. The exchange product is then benzylated. Either a benzyl halide, e.g., p-isopropylbenzyl chloride, or a benzaldehyde, e.g., p-isopropylbenzaldehyde may be used. These compounds are specifically described in U.S. Pat. No. 4,002,769. They contain also a lower alkoxy group, e.g., methoxy. This can be introduced prior to the formation of the Grignard exchange product or at a later stage in the operation. Use of the exchange-type Grignard reaction enables elimination of several steps when producing the arylterpenoids from pinene as the terpene source, and consequent costs.

  提供了一种改进的生产生物活性芳基萜类化合物的过程，用于抑制蛹的羽化，例如，苍蝇蛹或蚊子蛹。该过程的特点是将具有末端不饱和键的萜类材料，例如双氢肉豆蔻烯（3,7-二甲基辛-1,6-二烯），与较低的烷基格氏试剂，例如正丙基氯化镁反应，形成格氏交换产物。然后对交换产物进行苄基化。可以使用苄卤化物，例如对异丙基苄氯，或苄醛，例如对异丙基苄醛。这些化合物在美国专利4,002,769中有具体描述。它们还含有一个较低的烷氧基团，例如甲氧基。这可以在形成格氏交换产物之前或在操作的后期引入。使用交换型格氏反应可以在从蒎烯作为萜类来源生产芳基萜类化合物时消除几个步骤，从而降低成本。
• Microcapsules and microencapsulation process
  申请人：STAUFFER CHEMICAL COMPANY

  公开号：EP0158449A1

  公开（公告）日：1985-10-16

  Novel microcapsules are disclosed in which a liquid material which is substantially insoluble in water is enclosed within a solid permeable shell of etherified urea-formaldehyde polymer, prepared by a process which comprises: (a) providing an organic solution comprising said material and a urea-formaldehyde prepolymer in which from about 50% to about 98% of the methylol groups of said prepolymer have been etherified with a C4-C10 alcohol; (b) creating an emulsion of said organic solution in an aqueous solution comprising water and a surface-active agent, wherein said emulsion comprises discrete droplets of said organic solution dispersed in said aqueous solution; (c) causing in situ self-condensation of said urea-formaldehyde prepolymers by adding to said emulsion an acidifying agent and maintaining said emulsion at a pH of between about 0 and about 4 for a sufficient period of time to allow substantial completion of in situ condensation of said resin prepolymers to convert the liquid droplets of said organic solution to capsules consisting of solid permeable polymer shells enclosing said liquid material; and (d) heating said emulsion to a temperature between about 20°C and about 100°C to cause curing of said in situ formed polymers.

  本发明公开了一种新型微胶囊，在这种微胶囊中，基本上不溶于水的液态材料被包裹在由醚化脲醛聚合物构成的固体可渗透外壳中，其制备过程包括(a) 提供一种有机溶液，该有机溶液包括所述材料和脲醛预聚物，其中所述预聚物约 50% 至约 98% 的甲醇基团已被 C4-C10 醇醚化；(b) 在由水和表面活性剂组成的水溶液中形成所述有机溶液的乳液，其中所述乳液包括分散在所述水溶液中的所述有机溶液的离散液滴；(c) 通过向所述乳液中添加酸化剂，并将所述乳液的 pH 值保持在约 0 至约 4 之间足够长的时间，使所述树脂预聚物的原位缩合基本完成，从而将所述有机溶液的液滴转化为由固态可渗透聚合物外壳组成的胶囊，将所述液态材料包裹起来，从而使所述脲醛预聚物原位自缩合；以及 (d) 将所述乳液加热至约 20°C 至约 100°C 之间的温度，使所述原位形成的聚合物固化。
• CARDENAS, C. G.;HO, TSE-LOK;LIU, SHING-HOU
  作者：CARDENAS, C. G.、HO, TSE-LOK、LIU, SHING-HOU

  DOI：——

  日期：——
• AGUINAGA G. M.; DINIZO S. E., J. LABELLED COMPOUNDS AND RADIOPHARM., 24,(1987) N 5, 577-586
  作者：AGUINAGA G. M.、 DINIZO S. E.

  DOI：——

  日期：——
• Method for preparation of 8-methoxy-4,8-dimethyl-1-(4-isopropylphenyl)-nonane
  申请人：STAUFFER CHEMICAL COMPANY

  公开号：EP0116370B1

  公开（公告）日：1986-07-23