2-(2'-hydroxyphenyl)-4-methylquinoline | 14365-90-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 2-(2'-hydroxyphenyl)-4-methylquinoline
• 英文别名: 2-(4'-methylquinolinyl)-2-phenol；2-(4-methyl-quinolin-2-yl)-phenol；4-Methyl-2-<2-hydroxy-phenyl>-chinolin；2-(4-Methylquinolin-2-yl)phenol
• CAS: 14365-90-3
• 化学式: C₁₆H₁₃NO
• mdl: MFCD28338982
• 分子量: 235.285
• InChiKey: WJBCODKKUGWKTP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  18
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.062
• 拓扑面积：
  33.1
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2-(2'-hydroxyphenyl)-4-methylquinoline 、 三苯基硼烷 以 四氢呋喃 为溶剂， 以74%的产率得到BPh2(2-(4'-methylquinolinyl)-2-phenolato)
  参考文献：
  名称：

  Syntheses, Structures, and Luminescence/Electroluminescence of BPh₂(mqp), Al(CH₃)(mqp)₂, and Al(mqp)₃ (mqp = 2-(4‘-Methylquinolinyl)-2-phenolato)

  摘要：

  Three new complexes BPh2(mqp) (1), Al(CH3)(mqp)(2) (2), and AZ(mqp)(3) (3) have been;: synthesized and characterized, where mqp = 2-(4'-methylquinolinyl)-2-phenolato. The mqp ligand in compounds 1 and 2 act as a chelate ligand, while in compound 3 it acts as both a chelate ligand and a terminal ligand. The boron center in 1 has tetrahedral geometry, while the aluminum ion in 2 and 3 has trigonal-bipyramidal geometry. In CH2Cl2 solution, these compounds emit a green, a green-blue, and a whitish blue color (lambda = 514, 515; 497 nm), respectively, when irradiated by UV light. In the solid state, these three compounds emit. green, a blue, and a whitish blue color, respectively (lambda = 520, 474, 500 nm). Electroluminescent devices using compound 3 as an emitter have been fabricated.

  DOI：

  10.1021/om0006918
• 作为产物：
  描述：

  邻氨基苯乙酮 、 2'-羟基苯乙酮 在 盐酸 、 silica gel 作用下， 以 水 为溶剂， 反应 1.0h， 以51%的产率得到2-(2'-hydroxyphenyl)-4-methylquinoline
  参考文献：
  名称：

  Synthesis of Polysubstituted Analogues of the 4-Methyl-2-phenylquinoline

  摘要：

  报告采用一种简单方便的合成方法，直接合成了一系列 4-甲基-2-苯基喹啉（一种天然生物活性 4-甲氧基-2-苯基喹啉的模拟物）的多取代类似物。

  DOI：

  10.14233/ajchem.2013.14253

文献信息

• Synthesis of Polysubstituted Analogues of the 4-Methyl-2-phenylquinoline
  作者：A.A. Al-Qahtani、T.M. Al-Turki、M. Khan、A.A. Mousa、H.Z. Alkhathlan

  DOI：10.14233/ajchem.2013.14253

  日期：——

  A simple and convenient synthetic method for the direct synthesis of a series of polysubstituted analogues of the putative antifungal agent 4-methyl-2-phenylquinoline, a mimic of the natural bioactive 4-methoxy-2-phenylquinoline is reported.

  报告采用一种简单方便的合成方法，直接合成了一系列 4-甲基-2-苯基喹啉（一种天然生物活性 4-甲氧基-2-苯基喹啉的模拟物）的多取代类似物。
• Syntheses, Structures, and Luminescence/Electroluminescence of BPh₂(mqp), Al(CH₃)(mqp)₂, and Al(mqp)₃ (mqp = 2-(4‘-Methylquinolinyl)-2-phenolato)
  作者：Shi-Feng Liu、Corey Seward、Hany Aziz、Nan-Xing Hu、Zoran Popović、Suning Wang

  DOI：10.1021/om0006918

  日期：2000.12.1

  Three new complexes BPh2(mqp) (1), Al(CH3)(mqp)(2) (2), and AZ(mqp)(3) (3) have been;: synthesized and characterized, where mqp = 2-(4'-methylquinolinyl)-2-phenolato. The mqp ligand in compounds 1 and 2 act as a chelate ligand, while in compound 3 it acts as both a chelate ligand and a terminal ligand. The boron center in 1 has tetrahedral geometry, while the aluminum ion in 2 and 3 has trigonal-bipyramidal geometry. In CH2Cl2 solution, these compounds emit a green, a green-blue, and a whitish blue color (lambda = 514, 515; 497 nm), respectively, when irradiated by UV light. In the solid state, these three compounds emit. green, a blue, and a whitish blue color, respectively (lambda = 520, 474, 500 nm). Electroluminescent devices using compound 3 as an emitter have been fabricated.