7-azabenz[a]anthracene-7-oxide | 184424-54-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 7-azabenz[a]anthracene-7-oxide
• 英文别名: 7-Oxo-7lambda~5~-benzo[a]acridine；7-oxidobenzo[a]acridin-7-ium
• CAS: 184424-54-2
• 化学式: C₁₇H₁₁NO
• 分子量: 245.28
• InChiKey: WMDYMRRQFKPUSP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  19
• 可旋转键数：
  0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  25.5
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  苯并[a]吖啶 在 间氯过氧苯甲酸 作用下， 以 氯仿 为溶剂， 反应 2.0h， 以41%的产率得到7-azabenz[a]anthracene-7-oxide
  参考文献：
  名称：

  Studies on Nitrogen-containing Heterocyclic Compounds. Novel Synthesis of Naphtho[1,2-b and 2,1-b][1,8]naphthyridines and Oxidation Reactions with Peroxy Acids

  摘要：

  A modified Friedlander condensation of 2-aminonicotinaldehyde with alpha- and beta-naphthols lead successfully to two new naphtho[1,2-b and 2,1-b][1,8]-naphthyridines in a single synthetic procedure. The oxidation of the naphthonaphthyridines with peroxy acids afforded novel products such as a seven-membered oxazepine moiety. Structures were characterized by standard spectroscopy. The crystal and molecular structures (3) and (4) were determined by X-ray analyses.

  DOI：

  10.3987/com-96-7525

文献信息

• Studies on Nitrogen-containing Heterocyclic Compounds. Novel Synthesis of Naphtho[1,2-b and 2,1-b][1,8]naphthyridines and Oxidation Reactions with Peroxy Acids
  作者：Isao Takeuchi、Koosuke Asai、Yoshiki Hamada、Katsuyoshi Masuda、Hiroko Suezawa、Minoru Hirota、Yukihisa Kurono、Keiichiro Hatano

  DOI：10.3987/com-96-7525

  日期：——

  A modified Friedlander condensation of 2-aminonicotinaldehyde with alpha- and beta-naphthols lead successfully to two new naphtho[1,2-b and 2,1-b][1,8]-naphthyridines in a single synthetic procedure. The oxidation of the naphthonaphthyridines with peroxy acids afforded novel products such as a seven-membered oxazepine moiety. Structures were characterized by standard spectroscopy. The crystal and molecular structures (3) and (4) were determined by X-ray analyses.