hexadecan-1,11-diol | 39516-55-7

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: hexadecan-1,11-diol
• 英文别名: 1,11-Dihydroxyhexadecan；Hexadecane-1,11-diol
• CAS: 39516-55-7
• 化学式: C₁₆H₃₄O₂
• 分子量: 258.445
• InChiKey: IUWSNAXDRZNTEW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.4
• 重原子数：
  18
• 可旋转键数：
  14
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  hexadecan-1,11-diol 在 sodium tetrahydroborate 、 jones reagent 作用下， 以 甲醇 、 丙酮 为溶剂， 反应 0.5h， 生成 甲基11-羟基十六烷酸酯
  参考文献：
  名称：

  Products of Cytochrome P450_BioI (CYP107H1)-Catalyzed Oxidation of Fatty Acids

  摘要：

  [GRAPHICS]Oxidation of tetradecanoic and hexadecanoic acids by cytochrome P450(Biol) (CYP107H1) produces mainly the 11-, 12-, and 13-hydroxy C-14 fatty acids and the 11- to 15-hydroxy C-16 fatty acids, respectively. In contrast to previous reports, terminal hydroxylation is not observed. The enantiospecificity of fatty acid hydroxylation by P450(Biol) was also determined, and the enzyme was shown to be moderately selective for production of the (R)-alcohols.

  DOI：

  10.1021/ol035254e
• 作为产物：
  描述：

  10-十一烯-1-醇 在 dimethyl sulfide borane 、 sodium acetate 、 对甲苯磺酸 、 pyridinium chlorochromate 作用下， 以 四氢呋喃 、 乙醚 、 二氯甲烷 为溶剂， 反应 25.08h， 生成 hexadecan-1,11-diol
  参考文献：
  名称：

  Products of Cytochrome P450_BioI (CYP107H1)-Catalyzed Oxidation of Fatty Acids

  摘要：

  [GRAPHICS]Oxidation of tetradecanoic and hexadecanoic acids by cytochrome P450(Biol) (CYP107H1) produces mainly the 11-, 12-, and 13-hydroxy C-14 fatty acids and the 11- to 15-hydroxy C-16 fatty acids, respectively. In contrast to previous reports, terminal hydroxylation is not observed. The enantiospecificity of fatty acid hydroxylation by P450(Biol) was also determined, and the enzyme was shown to be moderately selective for production of the (R)-alcohols.

  DOI：

  10.1021/ol035254e

文献信息

• ALKYL DIOLS FOR CRUDE OIL TREATMENT
  申请人：Ecolab USA Inc.

  公开号：US20170233666A1

  公开（公告）日：2017-08-17

  The present invention generally relates to methods and compounds for reducing paraffin or wax deposition in crude oil during processing, storage, or transportation. More specifically, the method comprises contacting the crude oil with a composition in an amount effective to reduce paraffin or was deposition.
• US4127512A
  申请人：——

  公开号：US4127512A

  公开（公告）日：1978-11-28
• [EN] SELF-STABILISED MULTIPHASE EMUSION STRUCTURES
  申请人：THOREL, Jean-Noël

  公开号：WO1993002666A1

  公开（公告）日：1993-02-18

  (EN) Emulsion structure comprising at least three phases of which at least two are miscible with each other, at least one of said phases containing at least one active compound, characterised in that it is self-stabilised by at least one lamelar or multilamelar protection coating, having particularly a mesophase structure, providing an interface separation between unmiscible phases, arranged at an interface of the emulsion where the miscible phases can meet in the case of failure of an intermediary phase arranged between the latter and unmiscible with the phases on either side of said interface.(FR) Structure d'émulsion comprenant au moins trois phases, dont au moins deux sont miscibles entre elles, au moins l'une desdites phases pouvant contenir au moins un composé actif, caractérisée en ce qu'elle est autostabilisée par au moins un enrobage de protection lamellaire ou multilamellaire, ayant notamment une structure mésophasique, assurant une séparation interfaciale entre phases non miscibles, disposé à une interface de l'émulsion où les phases miscibles sont susceptibels de se rencontrer en cas de défaillance d'une phase intermédiaire disposée entre ces dernières, et non miscible avec les phases de part et d'autre de ladite interface.
• [EN] ALKYL DIOLS FOR CRUDE OIL TREATMENT<br/>[FR] ALKYL DIOLS POUR LE TRAITEMENT DE PÉTROLE BRUT
  申请人：ECOLAB USA INC

  公开号：WO2017143132A1

  公开（公告）日：2017-08-24

  The present invention generally relates to methods and compounds for reducing paraffin or wax deposition in crude oil during processing, storage, or transportation. More specifically, the method comprises contacting the crude oil with a composition in an amount effective to reduce paraffin or was deposition.
• Products of Cytochrome P450_BioI (CYP107H1)-Catalyzed Oxidation of Fatty Acids
  作者：Max J. Cryle、Nick J. Matovic、James J. De Voss

  DOI：10.1021/ol035254e

  日期：2003.9.1

  [GRAPHICS]Oxidation of tetradecanoic and hexadecanoic acids by cytochrome P450(Biol) (CYP107H1) produces mainly the 11-, 12-, and 13-hydroxy C-14 fatty acids and the 11- to 15-hydroxy C-16 fatty acids, respectively. In contrast to previous reports, terminal hydroxylation is not observed. The enantiospecificity of fatty acid hydroxylation by P450(Biol) was also determined, and the enzyme was shown to be moderately selective for production of the (R)-alcohols.