methyl 7-(trifluoromethyl)-5-{[(trifluoromethyl)sulfonyl]oxy}pyrazolo[1,5-a]pyridine-2-carboxylate | 1297137-02-0

分子结构分类

有机化合物 - 有机杂环化合物 - 吡唑并吡啶类

中文名称

——

中文别名

——

英文名称

methyl 7-(trifluoromethyl)-5-{[(trifluoromethyl)sulfonyl]oxy}pyrazolo[1,5-a]pyridine-2-carboxylate

英文别名

Methyl 7-(trifluoromethyl)-5-(trifluoromethylsulfonyloxy)pyrazolo[1,5-a]pyridine-2-carboxylate；methyl 7-(trifluoromethyl)-5-(trifluoromethylsulfonyloxy)pyrazolo[1,5-a]pyridine-2-carboxylate

methyl 7-(trifluoromethyl)-5-{[(trifluoromethyl)sulfonyl]oxy}pyrazolo[1,5-a]pyridine-2-carboxylate化学式

CAS

1297137-02-0

化学式

C₁₁H₆F₆N₂O₅S

mdl

——

分子量

392.235

InChiKey

GZQAWAGSFYUULC-UHFFFAOYSA-N

BEILSTEIN

——

EINECS

——

物化性质

密度：

1.73±0.1 g/cm3(Predicted)

计算性质

辛醇/水分配系数(LogP)：

2.9
重原子数：

25
可旋转键数：

4
环数：

2.0
sp3杂化的碳原子比例：

0.27
拓扑面积：

95.4
氢给体数：

0
氢受体数：

12

上下游信息

上游原料

中文名称	英文名称	CAS号	化学式	分子量
——	5-(methyloxy)-7-(trifluoromethyl)pyrazolo[1,5-a]pyridine-2-carboxylic acid	1297136-82-3	C₁₀H₇F₃N₂O₃	260.172
——	dimethyl 5-(methyloxy)-7-(trifluoromethyl)pyrazolo[1,5-a]pyridine-2,3-dicarboxylate	1297136-80-1	C₁₃H₁₁F₃N₂O₅	332.236
——	dimethyl 7-(trifluoromethyl)pyrazolo[1,5-a]pyridine-2,3-dicarboxylate	1268521-95-4	C₁₂H₉F₃N₂O₄	302.21
——	3-chloro-5-cyclopropyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyridine-2-carboxylic acid	1297137-35-9	C₁₂H₈ClF₃N₂O₂	304.656
——	dimethyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyridine-2,3-dicarboxylate	1297138-86-3	C₁₈H₂₀BF₃N₂O₆	428.173

下游产品

中文名称	英文名称	CAS号	化学式	分子量
——	5-(methyloxy)-7-(trifluoromethyl)pyrazolo[1,5-a]pyridine-2-carboxylic acid	1297136-82-3	C₁₀H₇F₃N₂O₃	260.172
5-环丙基-7-(三氟甲基)吡唑并[1,5-a]吡啶-2-羧酸甲酯	methyl 5-cyclopropyl-7-(trifluoromethyl)pyrazolo [1,5-a]pyridine-2-carboxylate	1297137-03-1	C₁₃H₁₁F₃N₂O₂	284.238
——	dimethyl 5-(methyloxy)-7-(trifluoromethyl)pyrazolo[1,5-a]pyridine-2,3-dicarboxylate	1297136-80-1	C₁₃H₁₁F₃N₂O₅	332.236
——	methyl 5-cyclopropyl-3-hydroxy-7-(trifluoromethyl)pyrazolo[1,5-a]pyridine-2-carboxylate	1297140-96-5	C₁₃H₁₁F₃N₂O₃	300.237
——	5-cyclopropyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyridine-2-carboxylic acid	1297137-04-2	C₁₂H₉F₃N₂O₂	270.211
——	methyl 5-cyclopropyl-3-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyridine-2-carboxylate	1297139-44-6	C₁₄H₁₃F₃N₂O₂	298.265
——	methyl 5-cyclopropyl-3-(methyloxy)-7-(trifluoromethyl)pyrazolo[1,5-a]pyridine-2-carboxylate	1297140-99-8	C₁₄H₁₃F₃N₂O₃	314.264
3-氯-5-环丙基-7-(三氟甲基)吡唑并[1,5-a]吡啶-2-羧酸甲酯	methyl 3-chloro-5-cyclopropyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyridine-2-carboxylate	1297137-34-8	C₁₃H₁₀ClF₃N₂O₂	318.683
——	5-cyclopropyl-3-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyridine-2-carboxylic acid	1297139-46-8	C₁₃H₁₁F₃N₂O₂	284.238
——	5-cyclopropyl-3-(methyloxy)-7-(trifluoromethyl)pyrazolo[1,5-a]pyridine-2-carboxylic acid	1297141-01-5	C₁₃H₁₁F₃N₂O₃	300.237
——	3-chloro-5-cyclopropyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyridine-2-carboxylic acid	1297137-35-9	C₁₂H₈ClF₃N₂O₂	304.656
——	3-(1-{[5-(methyloxy)-7-(trifluoromethyl)pyrazolo[1,5-a]pyridine-2-yl]carbonyl}-4-piperidinyl)-1,3-oxazolidin-2-one	1297136-74-3	C₁₈H₁₉F₃N₄O₄	412.368
——	3-(1-{[3-chloro-5-(methyloxy)-7-(trifluoromethyl)pyrazolo[1,5-a]pyridine-2-yl]carbonyl}-4-piperidinyl)-1,3-oxazolidin-2-one	1297136-88-9	C₁₈H₁₈ClF₃N₄O₄	446.814
——	3-(1-{[3-bromo-5-(methyloxy)-7-(trifluoromethyl)pyrazolo[1,5-a]pyridine-2-yl]carbonyl}-4-piperidinyl)-1,3-oxazolidin-2-one	1297136-83-4	C₁₈H₁₈BrF₃N₄O₄	491.265
——	3-(1-{[3,4-dichloro-5-(methyloxy)-7-(trifluoromethyl)pyrazolo[1,5-a]pyridine-2-yl]carbonyl}-4-piperidinyl)-1,3-oxazolidin-2-one	1297136-90-3	C₁₈H₁₇Cl₂F₃N₄O₄	481.259
——	4-(4-{[3-chloro-5-cyclopropyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyridin-2-yl]carbonyl}-2-oxo-1-piperazinyl)-3-fluorophenyl trifluoromethanesulfonate	1297141-41-3	C₂₃H₁₆ClF₇N₄O₅S	628.912
——	1-cyclobutyl-4-{[5-cyclopropyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyridine-2-yl]carbonyl}-2-piperazinone	1297137-14-4	C₂₀H₂₁F₃N₄O₂	406.408
——	1-cyclopentyl-4-{[5-cycIopropyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyridine-2-yl]carbonyl}-2-piperazinone	1297137-08-6	C₂₁H₂₃F₃N₄O₂	420.434
——	4-{[5-cyclopropyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyridine-2-yl]carbonyl}-1-(3-methylcyclobutyl)-2-piperazinone	1297137-19-9	C₂₁H₂₃F₃N₄O₂	420.434
——	4-{[3-bromo-5-cyclopropyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyridine-2-yl]carbonyl}-1-cyclobutyl-2-piperazinone	1297137-17-7	C₂₀H₂₀BrF₃N₄O₂	485.304
——	4-{[3-bromo-5-cycIopropyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyridine-2-yl]carbonyl}-1-cyclopentyl-2-piperazinone	1297137-09-7	C₂₁H₂₂BrF₃N₄O₂	499.33
——	4-{[3-chloro-5-cyclopropyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyridin-2-yl]carbonyl}-1-(3-cyclopenten-1-yl)-2-piperazinone	1297138-91-0	C₂₁H₂₀ClF₃N₄O₂	452.864
——	4-{[3-bromo-5-cyclopropyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyridine-2-yl]carbonyl}-1-(3-methylcyclobutyl)-2-piperazinone	1297137-25-7	C₂₁H₂₂BrF₃N₄O₂	499.33
——	4-{[3-chloro-5-cyclopropyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyridine-2-yl]carbonyl}-1-cyclobutyl-2-piperazinone	1297137-18-8	C₂₀H₂₀ClF₃N₄O₂	440.853
——	(trans-)-3-[(4-{[3-chloro-5-cyclopropyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyridin-2-yl]carbonyl}-1-piperazinyl)carbonyl]cyclobutanol	1431285-56-1	C₂₁H₂₂ClF₃N₄O₃	470.879
——	3-(1-{[5-cyclopropyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyridine-2-yl]carbonyl}-4-piperidinyl)-1,3-oxazolidine-2,4-dione	1297136-98-1	C₂₀H₁₉F₃N₄O₄	436.39
——	4-{[3-chloro-5-cycIopropyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyridine-2-yl]carbonyl}-1-cyclopentyl-2-piperazinone	1297137-13-3	C₂₁H₂₂ClF₃N₄O₂	454.879
——	3-(1-{[5-cyclopropyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyridine-2-yl]carbonyl}-4-piperidinyl)-1,3-oxazolidin-2-one	1297136-92-5	C₂₀H₂₁F₃N₄O₃	422.407
——	4-{[3-chloro-5-cyclopropyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyridin-2-yl]carbonyl}-1-[2-fluoro-4-hydroxyphenyl]-2-piperazinone	1297141-30-0	C₂₂H₁₇ClF₄N₄O₃	496.849
——	4-{[3-chloro-5-cyclopropyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyridin-2-yl]carbonyl}-1-(3-methylcyclobutyl)-2-piperazinone	1297137-28-0	C₂₁H₂₂ClF₃N₄O₂	454.879