6,9,15,18-tetraoxa-12,25-diazatetracyclo[21.3.1.0(5,26).0(19,24)]heptacosa-1(26),2,4,19,21,23(27),24-heptaene | 1315451-42-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 6,9,15,18-tetraoxa-12,25-diazatetracyclo[21.3.1.0(5,26).0(19,24)]heptacosa-1(26),2,4,19,21,23(27),24-heptaene
• 英文别名: 6,9,15,18-Tetraoxa-12,25-diazatetracyclo[21.3.1.05,26.019,24]heptacosa-1(27),2,4,19,21,23,25-heptaene；6,9,15,18-tetraoxa-12,25-diazatetracyclo[21.3.1.05,26.019,24]heptacosa-1(27),2,4,19,21,23,25-heptaene
• CAS: 1315451-42-3
• 化学式: C₂₁H₂₄N₂O₄
• 分子量: 368.433
• InChiKey: GALFVBUYDYBQON-UHFFFAOYSA-N

物化性质

• 熔点：
  152-154 °C(Solvent: Acetone)
• 沸点：
  592.4±50.0 °C(Predicted)
• 密度：
  1.160±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  27
• 可旋转键数：
  0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  61.8
• 氢给体数：
  1
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  (3-iodopropyl)triethoxysilane 、 6,9,15,18-tetraoxa-12,25-diazatetracyclo[21.3.1.0(5,26).0(19,24)]heptacosa-1(26),2,4,19,21,23(27),24-heptaene 在 三乙胺 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 12.0h， 以90%的产率得到12-[3-(triethoxysilyl)propyl]-6,9,15,18-tetraoxa-12,25-diazatetracyclo[21.3.1.0(5,26).0(19,24)]heptacosa-1(26),2,4,19,21,23(27),24-heptaene
  参考文献：
  名称：

  Synthesis of silica gel-bound acridino-18-crown-6 ether and preliminary studies on its metal ion selectivity

  摘要：

  Starting from commercially available and relatively cheap chemicals a novel silica gel-bound acridino-18-crown-6 ether was prepared. Selectivity of the latter stationary phase toward different metal ions was studied. The stationary phase showed appreciable selectivity for Ag+, Cu2+, and Hg2+ ions. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2011.05.050
• 作为产物：
  描述：

  1,11-bis(4-tolylsulphonyloxy)-6-(4-tolylsulphonyl)-3,9-dioxa-6-azaundecane 在 sodium 、 potassium carbonate 作用下， 以 丙醇 、 N,N-二甲基甲酰胺 为溶剂， 反应 73.0h， 生成 6,9,15,18-tetraoxa-12,25-diazatetracyclo[21.3.1.0(5,26).0(19,24)]heptacosa-1(26),2,4,19,21,23(27),24-heptaene
  参考文献：
  名称：

  Synthesis of silica gel-bound acridino-18-crown-6 ether and preliminary studies on its metal ion selectivity

  摘要：

  Starting from commercially available and relatively cheap chemicals a novel silica gel-bound acridino-18-crown-6 ether was prepared. Selectivity of the latter stationary phase toward different metal ions was studied. The stationary phase showed appreciable selectivity for Ag+, Cu2+, and Hg2+ ions. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2011.05.050

文献信息

• Synthesis and metal ion complexation of spin labeled 18-crown-6 ethers containing an acridone or an acridine fluorophore unit
  作者：Júlia Kertész、Balázs Bognár、Attila Kormos、Ildikó Móczár、Péter Baranyai、Miklós Kubinyi、Tamás Kálai、Kálmán Hideg、Péter Huszthy

  DOI：10.1016/j.tet.2011.09.092

  日期：2011.11

  Double (spin and fluorescence) labeled pyrroline derivatives of crown ethers containing an acridone or an acridine fluorophore unit (1 and 2) and their diamagnetic analogues (3 and 4) were synthesized. Their fluorescent behavior as well as their complexation properties toward selected metal ions (Na+, K+, Mg2+, Ca2+, Zn2+) were examined.

  合成了含有a啶酮或a啶荧光团单元（1和2）及其抗磁性类似物（3和4）的冠醚的双（旋转和荧光）标记的吡咯啉衍生物。研究了它们的荧光行为以及对选定的金属离子（Na +，K +，Mg 2 +，Ca 2 +，Zn 2+）的络合特性。
• Synthesis of silica gel-bound acridino-18-crown-6 ether and preliminary studies on its metal ion selectivity
  作者：Júlia Kertész、Péter Huszthy、Attila Kormos、László Bezúr

  DOI：10.1016/j.tet.2011.05.050

  日期：2011.7

  Starting from commercially available and relatively cheap chemicals a novel silica gel-bound acridino-18-crown-6 ether was prepared. Selectivity of the latter stationary phase toward different metal ions was studied. The stationary phase showed appreciable selectivity for Ag+, Cu2+, and Hg2+ ions. (C) 2011 Elsevier Ltd. All rights reserved.