4-aminomethyl-heptan-4-ol | 412016-63-8

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 4-aminomethyl-heptan-4-ol
• 英文别名: Aminomethyl-dipropyl-carbinol；4-(Aminomethyl)heptan-4-ol
• CAS: 412016-63-8
• 化学式: C₈H₁₉NO
• mdl: MFCD12169402
• 分子量: 145.245
• InChiKey: CIYZVUKFSLLVBP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  10
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  46.2
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  4-aminomethyl-heptan-4-ol 生成 N-(2-hydroxy-2-propyl-pentyl)-benzamide
  参考文献：
  名称：

  THE REACTION OF ETHYL GLYCINATE HYDROCHLORIDE WITH PRIMARY, SECONDARY, AND TERTIARY GRIGNARD REAGENTS¹

  摘要：

  DOI：

  10.1021/jo01203a004
• 作为产物：
  描述：

  甘氨酸乙酯盐酸盐 、 丙基氯化镁 在 乙醚 作用下， 生成 4-aminomethyl-heptan-4-ol
  参考文献：
  名称：

  THE REACTION OF ETHYL GLYCINATE HYDROCHLORIDE WITH PRIMARY, SECONDARY, AND TERTIARY GRIGNARD REAGENTS¹

  摘要：

  DOI：

  10.1021/jo01203a004

文献信息

• Stable and active complexes of adenosine and adenosine phosphates with aminoalcohols for the treatment of pulmonary artery hypertension, cardiac failure and other diseases
  申请人：Gorny Philipe

  公开号：US20050176675A1

  公开（公告）日：2005-08-11

  The invention is directed to compositions and methods which permit the oral use of adenosine and adenosine phosphates for cardiovascular applications such as pulmonary artery hypertension, cardiac failure and other diseases. Certain compositions in accordance with the invention have enhanced AMP gastrointestinal bioavailability and thus efficacy. The invention prolongs the activity of adenosine and adenosine phosphates when administered intravenously. In particular, the invention contemplates methods of treating several human (as well as animal) cardiovascular and neurological medical conditions that could be improved by an effective amount of adenosine, ATP or AMP combined with dialkylaminoalcohols and their salts.

  这项发明涉及允许口服腺苷和腺苷磷酸用于心血管应用，如肺动脉高压、心力衰竭和其他疾病的组合物和方法。根据该发明的某些组合物具有增强的AMP胃肠道生物利用度，因此具有更高的功效。该发明延长了静脉注射时腺苷和腺苷磷酸的活性。具体而言，该发明考虑了通过联合二烷基氨基醇及其盐与腺苷、ATP或AMP的有效量来改善几种人类（以及动物）心血管和神经系统医学状况的治疗方法。
• TRANSESTERIFICATION REACTION BY MEANS OF IRON CATALYST
  申请人：KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION

  公开号：US20170275241A1

  公开（公告）日：2017-09-28

  Provided is a catalyst for transesterification reactions, which contains an iron salen complex. Also provided is a method for producing an ester compound, which is characterized by carrying out a transesterification reaction between a starting material ester and a starting material alcohol with use of the catalyst.

  提供了一种用于酯交换反应的催化剂，其中包含铁Salen配合物。还提供了一种生产酯化合物的方法，其特点是利用该催化剂在起始物酯和起始物醇之间进行酯交换反应。
• PREPARATION OF N,N-(DI)ALKYLAMINOALKYL(METH)ACRYLAMIDE OR N,N-(DI)ALKYLAMINOALKYL (METH)ACRYLATE AND THE QUATERNARY AMMONIUM SALTS THEREOF AS FLOCCULATING AIDS AND GELLING AGENTS
  申请人：Evonik Roehm GmbH

  公开号：US20170369424A1

  公开（公告）日：2017-12-28

  N,N-(di)alkylaminoalkyl(meth)acrylamide or N,N-(di)alkylaminoalkyl (meth)acrylate and/or a quaternary ammonium salt thereof are prepared with a low content of a compound of formula (IV) wherein R 5 in each case is a linear, branched or cyclic alkyl radical, an aryl radical which may also be substituted by one or more alkyl groups, the linear, cyclic or branched alkyl radical may have a length of 1-12 carbon atoms and is, for example, methyl, ethyl, propyl, isopropyl, butyl, isobutyl, tert-butyl, pentyl, hexyl, heptyl, octyl, isooctyl, nonyl, decyl, undecyl, dodecyl.

  制备低含量的化合物公式（IV）其中R5在每种情况下都是线性，支链或环烷基，芳基，也可以被一个或多个烷基取代，线性，环状或支链烷基长度可以为1-12个碳原子，例如甲基，乙基，丙基，异丙基，丁基，异丁基，叔丁基，戊基，己基，庚基，异辛基，壬基，癸基。制备N，N-（二）烷基氨基烷基（甲基）丙烯酰胺或N，N-（二）烷基氨基烷基（甲基）丙烯酸酯和/或其季铵盐。
• METHOD OF INCREASING MASS TRANSFER RATE OF ACID GAS SCRUBBING SOLVENTS
  申请人：THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION

  公开号：US20140294705A1

  公开（公告）日：2014-10-02

  A method of increasing the overall mass transfer rate of acid gas scrubbing solids is disclosed. Various catalyst compounds for that purpose are also disclosed.

  本发明揭示了一种增加酸气洗涤固体的总传质速率的方法。还揭示了用于此目的的各种催化剂化合物。
• Aqueous coating composition based on a cationic amino urea resin, process for applying and baking the composition
  申请人：AKZO N.V.

  公开号：EP0135209A1

  公开（公告）日：1985-03-27

  The invention provides an aqueous coating composition based on a cationic amino urea resin having an amine number of 3-250 and obtained by reacting an organic isocyanate with a polyamino amide having an amine number of 40-500 and built up from a mono- or dicarboxylic acid and a polyamine, said composition also containing a solid particulate epoxy group-containing compound and/or a solid particulate polyester having a melting point of at least 40°C, The invention also pertains to the process for applying and baking said composition and to the coated substrate thus obtained.

  本发明提供了一种基于阳离子氨基脲树脂的水性涂料组合物，阳离子氨基脲树脂的胺数为3-250，由有机异氰酸酯与胺数为40-500的聚氨基酰胺反应而得，聚氨基酰胺由一元或二元羧酸和多胺组成、 本发明还涉及应用和烘烤上述组合物的工艺以及由此获得的涂层基材。