4-ethoxy-3-isopropylcyclobutene-1,2-dione | 906819-35-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 4-ethoxy-3-isopropylcyclobutene-1,2-dione
• 英文别名: 3-Ethoxy-4-propan-2-ylcyclobut-3-ene-1,2-dione
• CAS: 906819-35-0
• 化学式: C₉H₁₂O₃
• 分子量: 168.192
• InChiKey: PTDQSZVFWPUJLP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  43.4
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  4-ethoxy-3-isopropylcyclobutene-1,2-dione 、 N-苄基-N-(3-丁烯)胺 以 四氢呋喃 为溶剂， 以96%的产率得到3-(benzyl-but-3-enyl-amino)-4-isopropyl-cyclobut-3-ene-1,2-dione
  参考文献：
  名称：

  以方酸为平台聚合合成氮杂双环烯酮

  摘要：

  带有乙烯基酰胺部分的氮杂双环烯酮的合成是通过铑催化的环丁二烯与侧链烯烃的脱羰环加成反应而实现的。在微波加热条件下，由合适的方酸单酯和N-苄基烯基胺有效地制备了起始的环丁烯二酮。

  DOI：

  10.1002/adsc.200606097
• 作为产物：
  描述：

  方酸二乙酯 生成 4-ethoxy-3-isopropylcyclobutene-1,2-dione
  参考文献：
  名称：

  WO2006/88920

  摘要：

  公开号：

文献信息

• PHOTOELECTRIC CONVERSION ELEMENT, SOLAR CELL, AND COMPOUND
  申请人：FUJIFILM Corporation

  公开号：US20180144877A1

  公开（公告）日：2018-05-24

  Provided is a photoelectric conversion element including at least a first electrode that includes a conductive support, a photosensitive layer that contains a light absorbing agent, a hole transport layer that contains an organic hole transporting material, and a second electrode. At least one of the photosensitive layer or the hole transport layer is provided on the conductive support to constitute the first electrode in combination with the conductive support. The photosensitive layer includes at least a compound having a perovskite-type crystal structure that includes a cation of an element of Group 1 in the periodic table or a cationic organic group A, a cation of a metal atom M other than elements of Group 1 in the periodic table, and an anion of an anionic atom or atomic group X as the light absorbing agent. The hole transport layer includes at least a compound represented by the following Formula 1 as the organic hole transporting material.

  提供的是一种光电转换元件，其中至少包括一个包含导电支撑的第一电极，一个包含吸光剂的光敏层，一个包含有机空穴传输材料的空穴传输层，以及一个第二电极。光敏层或空穴传输层中至少有一层位于导电支撑上，与导电支撑结合形成第一电极。光敏层包括至少一种具有钙钛矿型晶体结构的化合物，其中包括周期表中第1族元素的阳离子或阳离子有机基团A，除了周期表第1族元素之外的金属原子M的阳离子，以及吸光剂的阴离子或原子团X。空穴传输层包括至少一种由以下式1表示的化合物作为有机空穴传输材料。
• RAS INHIBITORS AND USES THEREOF
  申请人：DANA-FARBER CANCER INSTITUTE, INC.

  公开号：US20160046661A1

  公开（公告）日：2016-02-18

  Described herein are compounds of Formulae (I)-(II), and pharmaceutically acceptable salts, and pharmaceutical compositions thereof. Also provided are methods and kits involving the inventive compounds or compositions for treating or preventing proliferative diseases such as cancers (e.g., lung cancer, large bowel cancer, pancreas cancer, biliary tract cancer, or endometrial cancer), benign neoplasms, angiogenesis, inflammatory diseases, autoinflammatory diseases, and autoimmune diseases in a subject.

  本文描述了式（I）-（II）的化合物，以及其药学上可接受的盐和制药组合物。还提供了涉及创新化合物或组合物的方法和工具包，用于治疗或预防受试者的增殖性疾病，如癌症（例如肺癌，大肠癌，胰腺癌，胆道癌或子宫内膜癌），良性肿瘤，血管生成，炎症性疾病，自身炎症性疾病和自身免疫性疾病。
• AMINE-LINKED PYRIDYL AND PHENYL SUBSTITUTED PIPERAZINE-PIPERIDINES WITH CXCR3 ANTAGONIST ACTIVITY
  申请人：Schering Corporation

  公开号：EP1853583B1

  公开（公告）日：2011-09-07
• HOST TARGETED INHIBITORS OF DENGUE VIRUS AND OTHER VIRUSES
  申请人：President and Fellows of Harvard College

  公开号：US20150166532A1

  公开（公告）日：2015-06-18

  Novel antiviral compounds of Formulae (I)-(III) are provided: (I) (II) (III) The inventive compounds, pharmaceutical compositions thereof, and kits including the inventive compounds are useful for the prevention and treatment of infectious diseases caused by viruses, for example, by Flaviviridae virus (e.g., Dengue virus (DENY)), Kunjin virus, Japanese encephalitis virus, vesicular stomatitis virus (VSV), herpes simplex virus 1 (HSV-1), human cytomegalovirus (HCMV), poliovirus, Junin virus, Ebola virus, Marburg virus (MARV), Lassa fever virus (LASV), Venezuelan equine encephalitis virus (VEEV), or Rift Valley Fever virus (RVFV).
• US7566718B2
  申请人：——

  公开号：US7566718B2

  公开（公告）日：2009-07-28