1,4-dioxa-7,11-dithiacyclotridecan-9-ol | 137053-91-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1,4-dioxa-7,11-dithiacyclotridecan-9-ol
• CAS: 137053-91-9
• 化学式: C₉H₁₈O₃S₂
• 分子量: 238.372
• InChiKey: JZEAJODMCSDRMM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.4
• 重原子数：
  14
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  89.3
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  1,4-dioxa-7,11-dithiacyclotridecan-9-ol 在 草酰氯 、 二甲基亚砜 、 三乙胺 作用下， 以 二氯甲烷 为溶剂， 以40%的产率得到1,4-二氧杂-7,11-二硫杂环十三烷-9-酮
  参考文献：
  名称：

  Facile Transformation of the Hydroxy‐Substituted Oxathiacrown Ethers

  摘要：

  9(12)-Hydroxy-dithia-13(16)-crown-4(6)-Eethers have been prepared by the condensing an oligoethylene glycol dithiol with 2,3-dibromo-1-propanol. Methods of oxidation, halogenation, amination, and esterification of the 9-hydroxythiacrown ether, producing corresponding oxathiacrown ether derivatives in good yields, have been developed. Cyclic destruction has not been found in the studied reactions. The change of the oxathiamacrocyclic ring size in the course of the halogenation and amination reactions was revealed.

  DOI：

  10.1080/00397910600640024
• 作为产物：
  描述：

  2,3-二溴-1-丙醇 、 2,2'-(1,2-乙二基双氧代)双乙硫醇 在 caesium carbonate 作用下， 以 乙醇 为溶剂， 反应 50.0h， 以67%的产率得到1,4-dioxa-7,11-dithiacyclotridecan-9-ol
  参考文献：
  名称：

  Synthesis, complex-formation, and extracting ability of new derivatives of dithia-13(16)-crown-4(5) ethers

  摘要：

  DOI：

  10.1007/s10593-006-0073-7

文献信息

• Synthesis, complex-formation, and extracting ability of new derivatives of dithia-13(16)-crown-4(5) ethers
  作者：E. V. Tulyakova、E. V. Rakhmanov、E. V. Lukovskaya、O. A. Fedorova、A. A. Abramov、A. V. Khoroshutin、A. A. Bobylyova、A. V. Anisimov

  DOI：10.1007/s10593-006-0073-7

  日期：2006.2
• Facile Transformation of the Hydroxy‐Substituted Oxathiacrown Ethers
  作者：Elena V. Tulyakova、Edward V. Rakhmanov、Elena V. Lukovskaya、Alla A. Bobylyova、Andrey V. Khoroshutin、Alexander V. Anisimov、Olga A. Fedorova

  DOI：10.1080/00397910600640024

  日期：2006.8

  9(12)-Hydroxy-dithia-13(16)-crown-4(6)-Eethers have been prepared by the condensing an oligoethylene glycol dithiol with 2,3-dibromo-1-propanol. Methods of oxidation, halogenation, amination, and esterification of the 9-hydroxythiacrown ether, producing corresponding oxathiacrown ether derivatives in good yields, have been developed. Cyclic destruction has not been found in the studied reactions. The change of the oxathiamacrocyclic ring size in the course of the halogenation and amination reactions was revealed.