methyl α-D-mannopyranosyl-(1->6)-2,3,4-tri-O-benzoyl-α-D-mannopyranoside | 311805-99-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: methyl α-D-mannopyranosyl-(1->6)-2,3,4-tri-O-benzoyl-α-D-mannopyranoside
• 英文别名: Man(a1-6)[Bz(-2)][Bz(-3)][Bz(-4)]a-Man1Me；[(2R,3R,4S,5S,6S)-4,5-dibenzoyloxy-6-methoxy-2-[[(2S,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-3-yl] benzoate
• CAS: 311805-99-9
• 化学式: C₃₄H₃₆O₁₄
• 分子量: 668.651
• InChiKey: HHSPXMXTOCCHNY-KAEDGDHVSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  48
• 可旋转键数：
  14
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  197
• 氢给体数：
  4
• 氢受体数：
  14

反应信息

• 作为反应物：
  描述：

  methyl α-D-mannopyranosyl-(1->6)-2,3,4-tri-O-benzoyl-α-D-mannopyranoside 在 吡啶 、 2,4-二甲基吡啶 、 silver trifluoromethanesulfonate 作用下， 以 二氯甲烷 为溶剂， 生成
  参考文献：
  名称：

  Regio- and Stereoselective Synthesis of 1→6 Linked Manno-, Gluco-, and Galactopyranose Di-, Tri-, and Tetrasaccharides Via Orthoester Intermediates

  摘要：

  1-->6 Linked manno-, gluco-, and galactopyranose di-, tri-, and tetrasaccharides with 1,2-trans glycosidic linkages were concisely and effectively synthesized using peracetylated glycosyl bromides as the donors and unprotected or partially protected glycopyranosides as the accepters via orthoester intermediates.

  DOI：

  10.1080/07328300008544122
• 作为产物：
  描述：

  2,3,4,6-四-O-乙酰基-1-溴-Alpha-D-甘露糖 在 吡啶 、 2,4-二甲基吡啶 、 三氟甲磺酸三甲基硅酯 、 silver trifluoromethanesulfonate 、 乙酰氯 作用下， 以 甲醇 、 二氯甲烷 、 N,N-二甲基甲酰胺 为溶剂， 反应 1.5h， 生成 methyl α-D-mannopyranosyl-(1->6)-2,3,4-tri-O-benzoyl-α-D-mannopyranoside
  参考文献：
  名称：

  Regio- and Stereoselective Synthesis of 1→6 Linked Manno-, Gluco-, and Galactopyranose Di-, Tri-, and Tetrasaccharides Via Orthoester Intermediates

  摘要：

  1-->6 Linked manno-, gluco-, and galactopyranose di-, tri-, and tetrasaccharides with 1,2-trans glycosidic linkages were concisely and effectively synthesized using peracetylated glycosyl bromides as the donors and unprotected or partially protected glycopyranosides as the accepters via orthoester intermediates.

  DOI：

  10.1080/07328300008544122

文献信息

• Regio- and Stereoselective Synthesis of 1→6 Linked Manno-, Gluco-, and Galactopyranose Di-, Tri-, and Tetrasaccharides Via Orthoester Intermediates
  作者：Yuliang Zhu、Fanzuo Kong

  DOI：10.1080/07328300008544122

  日期：2000.1

  1-->6 Linked manno-, gluco-, and galactopyranose di-, tri-, and tetrasaccharides with 1,2-trans glycosidic linkages were concisely and effectively synthesized using peracetylated glycosyl bromides as the donors and unprotected or partially protected glycopyranosides as the accepters via orthoester intermediates.