tert-butyl N-[5-methyl-3-[(2-methylpropan-2-yl)oxycarbonylamino]-6-phenyl-6H-phenanthridin-8-yl]carbamate | 1314080-93-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: tert-butyl N-[5-methyl-3-[(2-methylpropan-2-yl)oxycarbonylamino]-6-phenyl-6H-phenanthridin-8-yl]carbamate
• CAS: 1314080-93-7
• 化学式: C₃₀H₃₅N₃O₄
• 分子量: 501.626
• InChiKey: HJPHLQFFCIZHAO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.1
• 重原子数：
  37
• 可旋转键数：
  7
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  79.9
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  tert-butyl N-[5-methyl-3-[(2-methylpropan-2-yl)oxycarbonylamino]-6-phenyl-6H-phenanthridin-8-yl]carbamate 在 盐酸 作用下， 以 乙酸乙酯 为溶剂， 生成 氢乙啶
  参考文献：
  名称：

  [EN] DIHYDROETHIDINE ANALOGUES AND USES THEREOF
  [FR] ANALOGUES DE DIHYDROÉTHIDINE ET LEURS UTILISATIONS

  摘要：

  公开号：

  WO2011084585A3
• 作为产物：
  描述：

  3,8-二氨基-6-苯基菲啶 在 sodium cyanoborohydride 作用下， 以 四氢呋喃 为溶剂， 生成 tert-butyl N-[5-methyl-3-[(2-methylpropan-2-yl)oxycarbonylamino]-6-phenyl-6H-phenanthridin-8-yl]carbamate
  参考文献：
  名称：

  [EN] DIHYDROETHIDINE ANALOGUES AND USES THEREOF
  [FR] ANALOGUES DE DIHYDROÉTHIDINE ET LEURS UTILISATIONS

  摘要：

  公开号：

  WO2011084585A3

文献信息

• DIHYDROETHIDINE ANALOGUES AND USES THEREOF
  申请人：Mach Robert H.

  公开号：US20130079522A1

  公开（公告）日：2013-03-28

  Tracers for imaging distribution of reactive oxygen species (ROS) are disclosed. The tracers include radiolabeled dihydroethidine (DHE) analogues. Further disclosed are uses of the compounds, including methods of imaging tissue distribution of ROS in vivo by positron emission tomography (PET). Methods of synthesizing the compounds are also disclosed.
• COMPOUND OR SALT THEREOF
  申请人：SHIZUOKA PREFECTURAL UNIVERSITY CORPORATION

  公开号：US20220401590A1

  公开（公告）日：2022-12-22

  The present invention relates to a compound represented by the following General Formula (1) or a salt thereof. In General Formula (1), R 1 , R 2 , R 3 and R 4 each independently represent a hydrogen atom, a linear or branched alkyl group which may have a substituent or the like. R 1 and R 2 may be bonded to each other to form a ring. R 3 and R 4 may be bonded to each other to form a ring. R 1 and/or R 2 may be bonded to a 6-membered ring to which —NR 1 R 2 is bonded to form a ring. R 3 and/or R 4 may be bonded to a 6-membered ring to which —NR 3 R 4 is bonded to form a ring. R 5 represents — 11 CH 3 , a linear or branched alkyl group which may have a substituent or the like. R 6 represents —F, — 18 F or the like. X, Y and Z each independently represent a carbon atom, an oxygen atom or the like. n is 0 or 1.
• US9035057B2
  申请人：——

  公开号：US9035057B2

  公开（公告）日：2015-05-19
• [EN] DIHYDROETHIDINE ANALOGUES AND USES THEREOF<br/>[FR] ANALOGUES DE DIHYDROÉTHIDINE ET LEURS UTILISATIONS
  申请人：UNIV WASHINGTON

  公开号：WO2011084585A3

  公开（公告）日：2011-10-13