bis(D-galacto-2,3,4,5,6-pentahydroxyhexyl)amine | 106565-39-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: bis(D-galacto-2,3,4,5,6-pentahydroxyhexyl)amine
• 英文别名: 1,1'-imino-bis-(D-1-deoxy-galactitol)；Bis-(D_r-2c_F,4t_F,5r_F,6-pentahydroxy-hexyl)-amin；1,1'-Imino-bis-(D-1-desoxy-galactit)；Di-D-galactit-1-yl-amin；Di-D-galaktityl-(1)-amin；(2R,3S,4R,5S)-6-[[(2S,3R,4S,5R)-2,3,4,5,6-pentahydroxyhexyl]amino]hexane-1,2,3,4,5-pentol
• CAS: 106565-39-3
• 化学式: C₁₂H₂₇NO₁₀
• 分子量: 345.347
• InChiKey: KXONZRPGKNOGCG-NKUXFBMISA-N

物化性质

• 沸点：
  785.5±60.0 °C(Predicted)
• 密度：
  1.617±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -6
• 重原子数：
  23
• 可旋转键数：
  12
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  214
• 氢给体数：
  11
• 氢受体数：
  11

反应信息

• 作为反应物：
  描述：

  bis(D-galacto-2,3,4,5,6-pentahydroxyhexyl)amine 、 乙酸酐 以 水 为溶剂， 生成 N-Acetyl-di-D-galaktityl-(1)-amin
  参考文献：
  名称：

  Preparation and Properties of Dialditylamines¹

  摘要：

  DOI：

  10.1021/jo01045a071
• 作为产物：
  描述：

  galactose oxime 在 platinum on activated charcoal 氢气 作用下， 以 水 为溶剂， 50.0 ℃ 、10.13 MPa 条件下， 反应 24.0h， 以79.5%的产率得到bis(D-galacto-2,3,4,5,6-pentahydroxyhexyl)amine
  参考文献：
  名称：

  Formation of borate esters from, and sequestration of metal ions by, bis(polyhydroxyalkyl)amines and their N-carboxymethyl derivatives studied by 11B and 13C NMR spectroscopy

  摘要：

  Catalytic hydrogenation of aldose oximes affords bis(polyhydroxyalkyl)amines. These compounds and their N-carboxymethyl derivatives react with borate ions to give macrocyclic diborate diesters. The presence of an N-carboxymethyl group raises the capacities for the sequestration of Ca2+, Cu2+, and Cd2+. The N-carboxymethyl derivatives possess strong affinity for Ca2+ (pH > 11) and Cd2+ both in the absence and presence of borate.

  DOI：

  10.1016/0008-6215(93)87032-n

文献信息

• The Preparation of Glycamines¹
  作者：Fred Kagan、M. A. Rebenstorf、Richard V. Heinzelman

  DOI：10.1021/ja01570a063

  日期：1957.7
• Synthesis of Amino Compounds in the Sugar Series by Phenylhydrazone Reduction^1,2
  作者：M. L. WOLFROM、F. SHAFIZADEH、J. O. WEHRMÜLLER、R. K. ARMSTRONG

  DOI：10.1021/jo01098a019

  日期：1958.4
• Preparation and Properties of Dialditylamines¹
  作者：J. E. Hodge、B. F. Moy

  DOI：10.1021/jo01045a071

  日期：1963.10
• Formation of borate esters from, and sequestration of metal ions by, bis(polyhydroxyalkyl)amines and their N-carboxymethyl derivatives studied by 11B and 13C NMR spectroscopy
  作者：Jacco van Haveren、Hendrik Lammers、Joop A. Peters、Jan G. Batelaan、Herman van Bekkum

  DOI：10.1016/0008-6215(93)87032-n

  日期：1993.5

  Catalytic hydrogenation of aldose oximes affords bis(polyhydroxyalkyl)amines. These compounds and their N-carboxymethyl derivatives react with borate ions to give macrocyclic diborate diesters. The presence of an N-carboxymethyl group raises the capacities for the sequestration of Ca2+, Cu2+, and Cd2+. The N-carboxymethyl derivatives possess strong affinity for Ca2+ (pH > 11) and Cd2+ both in the absence and presence of borate.