5-acetoxy-pent-1-en-3-one | 100960-26-7

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 5-acetoxy-pent-1-en-3-one
• 英文别名: 5-Acetoxy-pent-1-en-3-on；3-Oxopent-4-enyl acetate
• CAS: 100960-26-7
• 化学式: C₇H₁₀O₃
• 分子量: 142.155
• InChiKey: ZTUQONZTUVRBCW-UHFFFAOYSA-N

物化性质

• 沸点：
  63-64 °C(Press: 3 Torr)
• 密度：
  1.0164 g/cm3

计算性质

• 辛醇/水分配系数(LogP)：
  0.4
• 重原子数：
  10
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  43.4
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  5-acetoxy-pent-1-en-3-one 在 硫酸 、 mercury(II) sulfate 作用下， 生成 四氢吡喃酮
  参考文献：
  名称：

  Conjugate intra- and intermolecular addition mediated by methoxide anion on polymeric support

  摘要：

  By treatment with methoxide anion on polymeric support (IRA 900), chiral beta -oxo or beta -sulphonylamides 2 bearing an alpha,beta -unsaturated ester gave 3,4-disubstituted pyrrolidin-2-ones 3 as easily separable diastereomeric mixtures in good yield and moderate-to-good stereoselection. The polymeric reagent was also effective in promoting both intermolecular conjugate addition and alkylation reactions. (C) 2000 Published by Elsevier Science Ltd.

  DOI：

  10.1016/s0040-4039(00)01490-8
• 作为产物：
  描述：

  1,5-二甲氧基-3-戊酮 、 乙酸酐 在 sodium acetate 、 溶剂黄146 作用下， 生成 5-acetoxy-pent-1-en-3-one 、 1,5-diacetoxy-pentan-3-one
  参考文献：
  名称：

  Conjugate intra- and intermolecular addition mediated by methoxide anion on polymeric support

  摘要：

  By treatment with methoxide anion on polymeric support (IRA 900), chiral beta -oxo or beta -sulphonylamides 2 bearing an alpha,beta -unsaturated ester gave 3,4-disubstituted pyrrolidin-2-ones 3 as easily separable diastereomeric mixtures in good yield and moderate-to-good stereoselection. The polymeric reagent was also effective in promoting both intermolecular conjugate addition and alkylation reactions. (C) 2000 Published by Elsevier Science Ltd.

  DOI：

  10.1016/s0040-4039(00)01490-8

文献信息

• Verfahren zur Herstellung von 2-Methyl-2-alkenalen
  申请人：BASF Aktiengesellschaft

  公开号：EP0211205B1

  公开（公告）日：1988-08-31
• US4677230A
  申请人：——

  公开号：US4677230A

  公开（公告）日：1987-06-30
• Conjugate intra- and intermolecular addition mediated by methoxide anion on polymeric support
  作者：Cristiana Fava、Roberta Galeazzi、Eugenia Maria Gonzalez-Rosende、Mario Orena

  DOI：10.1016/s0040-4039(00)01490-8

  日期：2000.10

  By treatment with methoxide anion on polymeric support (IRA 900), chiral beta -oxo or beta -sulphonylamides 2 bearing an alpha,beta -unsaturated ester gave 3,4-disubstituted pyrrolidin-2-ones 3 as easily separable diastereomeric mixtures in good yield and moderate-to-good stereoselection. The polymeric reagent was also effective in promoting both intermolecular conjugate addition and alkylation reactions. (C) 2000 Published by Elsevier Science Ltd.