2-甲基乳酸烯丙酯 | 19444-21-4

• 物质功能分类: 化学试剂 - 有机试剂 - 酯类
• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 2-甲基乳酸烯丙酯
• 英文名称: (2-propenyl) 2-hydroxyisobutyrate
• 英文别名: α-Hydroxy-isobuttersaeure-allylester；allyl 2-hydroxyisobutyrate；allyl hydroxyisobutyrate；α-hydroxy-isobutyric acid allyl ester；2-hydroxyisobutyric acid allyl ester；prop-2-enyl 2-hydroxy-2-methylpropanoate
• CAS: 19444-21-4
• 化学式: C₇H₁₂O₃
• 分子量: 144.17
• InChiKey: CTQMWJKOPOFOSX-UHFFFAOYSA-N

物化性质

• 沸点：
  166℃ (760 Torr)
• 密度：
  1.0040 g/cm3
• LogP：
  0.64 at 25℃
• 表面张力：
  49.6mN/m at 1g/L and 20℃

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  10
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

SDS

Name:	Allyl-2-(hydroxy)isobutyrate Material Safety Data Sheet
Synonym:	None
CAS:	19444-21-4

Section 1 - Chemical Product MSDS Name:Allyl-2-(hydroxy)isobutyrate Material Safety Data Sheet
Synonym:None

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Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS

CAS#	Chemical Name	content	EINECS#
19444-21-4	Allyl-2-(hydroxy)isobutyrate	95.0+	unlisted

Hazard Symbols: XN
Risk Phrases: 20/21/22

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Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Harmful by inhalation, in contact with skin and if swallowed.The toxicological properties of this material have not been fully investigated.
Potential Health Effects
Eye:
May cause eye irritation. The toxicological properties of this material have not been fully investigated.
Skin:
May cause skin irritation. The toxicological properties of this material have not been fully investigated.
Ingestion:
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated.
Inhalation:
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
Chronic:
No information found.

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Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Skin:
Get medical aid. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Wash clothing before reuse.
Ingestion:
If victim is conscious and alert, give 2-4 cupfuls of milk or water.
Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:

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Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
Use agent most appropriate to extinguish fire.

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Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Clean up spills immediately, observing precautions in the Protective Equipment section. Provide ventilation.

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Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.
Storage:
Keep containers tightly closed. Store in a cool, dry area away from incompatible substances.

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Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 19444-21-4: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

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Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Liquid
Color: clear colorless
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: 82-85C @ 52 mbar
Freezing/Melting Point: Not available.
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C7H12O3
Molecular Weight: 144.0822

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Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stability unknown.
Conditions to Avoid:
Incompatible materials.
Incompatibilities with Other Materials:
Strong oxidizing agents, strong bases.
Hazardous Decomposition Products:
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.
Hazardous Polymerization: Has not been reported.

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Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 19444-21-4 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
Allyl-2-(hydroxy)isobutyrate - Not listed by ACGIH, IARC, or NTP.

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Section 12 - ECOLOGICAL INFORMATION

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Section 13 - DISPOSAL CONSIDERATIONS
Products which are considered hazardous for supply are classified as Special Waste and the disposal of such chemicals is covered by regulations which may vary according to location. Contact a specialist disposal company or the local waste regulator for advice. Empty containers must be decontaminated before returning for recycling.

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Section 14 - TRANSPORT INFORMATION

IATA
No information available.
IMO
No information available.
RID/ADR
Shipping Name: Toxic liquid, organic, n.o.s.
Hazard Class: 6.1
UN Number: 2810
Packing group: III

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Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XN
Risk Phrases:
R 20/21/22 Harmful by inhalation, in contact with
skin and if swallowed.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 36/37/39 Wear suitable protective clothing, gloves
and eye/face protection.
WGK (Water Danger/Protection)
CAS# 19444-21-4: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 19444-21-4 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 19444-21-4 is not listed on the TSCA inventory.
It is for research and development use only.

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SECTION 16 - ADDITIONAL INFORMATION
N/A

反应信息

• 作为反应物：
  描述：

  2-甲基乳酸烯丙酯 在 TS-1 (crystalline titanosilicate) 双氧水 作用下， 以 甲醇 、 水 、 乙腈 为溶剂， 反应 2.0h， 以69.1%的产率得到glycidyl 2-hydroxyisobutyrate
  参考文献：
  名称：

  WO2007/4549

  摘要：

  公开号：
• 作为产物：
  描述：

  2-甲基-2-羟基丙酸 、 烯丙醇 在 苯 作用下， 生成 2-甲基乳酸烯丙酯
  参考文献：
  名称：

  Rehberg; Fisher; Smith, Journal of the American Chemical Society, 1943, vol. 65, p. 1005

  摘要：

  DOI：

文献信息

• 一种吡啶氧基羧酸酯衍生物及其制备方法、除 草组合物和应用
  申请人：青岛清原化合物有限公司

  公开号：CN109438333B

  公开（公告）日：2021-01-05

  本发明属于农药技术领域，具体涉及一种吡啶氧基羧酸酯衍生物及其制备方法、除草组合物和应用。所述吡啶氧基羧酸酯衍生物如式Ⅰ所示，其中，A、B分别独立地代表卤素，含有或不含有卤素的烷基或环烷基；C代表氢、卤素、烷基、卤代烷基；Q代表卤素，氰基，氰基烷基，羟基烷基，氨基，硝基，甲酰基，不含或含有卤素的烷基、烯基等；M代表‑烷基‑R、‑卤代烷基‑R、X代表硝基或NR1R2。所述化合物的除草活性优异，且具有更高的作物安全性，尤其是对于水稻、大豆等关键农作物建立了良好的选择性。
• PHOTOSENSITIVE RESIN COMPOSITION, PHOTOSENSITIVE RESIN LAYER USING THE SAME AND COLOR FILTER
  申请人：SAMSUNG SDI CO., LTD.

  公开号：US20200142301A1

  公开（公告）日：2020-05-07

  A photosensitive resin composition, a photosensitive resin layer, and a color filter, the composition including a colorant including a first green dye having a core-shell structure and a second green dye in a weight ratio of about 1:9 to about 7:3; a binder resin; a photopolymerizable compound; a photopolymerization initiator; and a solvent.

  一种感光树脂组合物、感光树脂层和彩色滤光片，该组合物包括一种颜料，其中包括具有核壳结构的第一绿色染料和第二绿色染料，其重量比约为1:9到7:3；一种粘合树脂；一种光聚合化合物；一种光聚合引发剂；和一种溶剂。
• NOVEL COMPOUND, CORE-SHELL DYE, PHOTOSENSITIVE RESIN COMPOSITION INCLUDING THE SAME, AND COLOR FILTER
  申请人：SAMSUNG SDI CO., LTD.

  公开号：US20200308099A1

  公开（公告）日：2020-10-01

  A compound represented by specific chemical formula, a core including the same, and core-shell dye including a shell surrounding the core, a photosensitive resin composition including the same, and a color filter manufactured using the photosensitive resin composition are disclosed.

  本发明公开了一种由特定化学配方表示的化合物，包括相同核心的核心和包围核心的壳层染料，包括该核心的光敏树脂组合物，以及使用该光敏树脂组合物制造的彩色滤光片。
• 氟丙嘧草酯的合成方法
  申请人：江苏省农用激素工程技术研究中心有限公司

  公开号：CN113336711B

  公开（公告）日：2022-04-08

  本发明公开了一种氟丙嘧草酯的合成方法，它是由2‑氯‑5‑（1,2,3,6‑四氢‑3‑甲基‑2,6‑二氧‑4‑三氟甲基嘧啶‑1‑基）苯甲酸甲酯与2‑羟基异丁酸丙烯酯在酯交换催化剂的存在下，经一步酯交换反应生成氟丙嘧草酯；其中，一步酯交换反应温度为90～130℃，反应时间为2～8h，酯交换催化剂为钛酸四异丙酯或者钛酸四异丁酯，2‑氯‑5‑（1,2,3,6‑四氢‑3‑甲基‑2,6‑二氧‑4‑三氟甲基嘧啶‑1‑基）苯甲酸甲酯与2‑羟基异丁酸丙烯酯的摩尔比为1∶4～1∶10。本发明的合成方法只需一步反应，大大缩短了反应步骤，提高了反应收率，而且相比于现有技术对环境更友好，适合于工业化生产。
• PROCESS FOR PRODUCTION OF METHACRYLIC ACID ESTERS
  申请人：ROHM AND HAAS COMPANY

  公开号：US20160102043A1

  公开（公告）日：2016-04-14

  A method for producing α-, β-unsaturated carboxylic acid esters in high yield from acetone cyanohydrin and sulfuric acid through the separation and concurrent catalytic conversion of reaction side products to additional α-, β-unsaturated carboxylic acid ester product. The catalyst comprises at least one Group IA element, and boron as a promoter, on a porous support.

  本发明提供了一种从丙酮氰醇和硫酸中高产率地制备α，β-不饱和羧酸酯的方法，通过分离和同时催化转化反应副产物为额外的α，β-不饱和羧酸酯产品。催化剂包括至少一个IA族元素和硼作为促进剂，位于多孔支撑体上。