Jurubidine | 6084-44-2

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: Jurubidine
• 英文别名: (1R,2S,4S,5'S,6R,7S,8R,9S,12S,13S,16S,18S)-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icosane-6,2'-oxane]-16-amine
• CAS: 6084-44-2
• 化学式: C₂₇H₄₅NO₂
• 分子量: 415.7
• InChiKey: BADUKLRFTFBRSD-PUHUBZITSA-N

物化性质

• 熔点：
  182-186 °C
• 沸点：
  506.6±20.0 °C(Predicted)
• 密度：
  1.09±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  6.2
• 重原子数：
  30
• 可旋转键数：
  0
• 环数：
  6.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  44.5
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• 美白剤及びこれを配合した皮膚外用剤
  申请人：株式会社資生堂

  公开号：JP2001019618A

  公开（公告）日：2001-01-23

  (57)【要約】\n【課題】 新規な美白剤及び美白効果に優れた皮膚外用剤を提供すること。\n【解決手段】 下記化学式（１）で表される化合物(25S)−3β−amino-5α,22αO−spirostan (ジュルビディン,jurubidine）若しくはその塩、又は、下記化学式（２）で表される化合物(25R)−3β−amino-5α,22αO−spirostan (イソジュルビディン,isojurubidine）若しくはその塩からなる美白剤。\n（１）\n（２）\n

  (57) [摘要] Јn[主题事项] 提供一种新型美白剂和一种具有良好美白效果的外用护肤品。\化合物 (25S)-3β-氨基-5α,22αO-螺甾烷（Jurubidine）或其盐由以下化学式 (1) 或以下化学式 (2) 表示一种美白剂，由以下化学式（2）代表的化合物（25R）-3β-氨基-5α，22αO-螺烷（异茹螨啶，isojurubidine）或其盐组成。\n(1)}n(2)}n
• DERMATOLOGICAL COMPOSITIONS WITH ANTI-AGING AND SKIN EVEN-TONING PROPERTIES
  申请人：Hinman Andrew W.

  公开号：US20100010100A1

  公开（公告）日：2010-01-14

  The present invention relates to methods and compositions comprising benzoquinones such as Duroquinone, for the use of treating, regulating or preventing a skin condition characterized by oxidative stress or a degenerative process. Methods of preventing, lightening or reducing the appearance of visible and/or tactile discontinuities of the skin resulting from skin pigmentation or skin aging are also disclosed.
• NAPHTHOQUINONE COMPOSITIONS WITH ANTI-AGING, ANTI-INFLAMMATORY AND SKIN EVEN-TONING PROPERTIES
  申请人：Hinman Andrew W.

  公开号：US20100029784A1

  公开（公告）日：2010-02-04

  The present invention relates to methods and compositions comprising naphthoquinones such as 2,3-dimethylnaphthalene-1,4-dione, for the use of treating, regulating or preventing a skin condition characterized by oxidative stress or a degenerative process. Methods of preventing, lightening or reducing the appearance of visible and/or tactile discontinuities of the skin resulting from skin pigmentation or skin aging are also disclosed.
• [EN] DERMATOLOGICAL COMPOSITIONS WITH ANTI-AGING AND SKIN EVEN-TONING PROPERTIES<br/>[FR] COMPOSITIONS DERMATOLOGIQUES AVEC DES PROPRIÉTÉS D'ANTIVIEILLISSEMENT ET D'HOMOGÉNÉISATION DE LA COULEUR DE LA PEAU
  申请人：EDISON PHARMACEUTICALS INC

  公开号：WO2010005989A1

  公开（公告）日：2010-01-14

  The present invention relates to methods and compositions comprising benzoquinones such as Duroquinone, for the use of treating, regulating or preventing a skin condition characterized by oxidative stress or a degenerative process. Methods of preventing, lightening or reducing the appearance of visible and/or tactile discontinuities of the skin resulting from skin pigmentation or skin aging are also disclosed.
• [EN] NAPHTHOQUINONE COMPOSITIONS WITH ANTI-AGING, ANTI- INFLAMMATORY AND SKIN EVEN-TONING PROPERTIES<br/>[FR] COMPOSITIONS DE NAPHTOQUINONE AVEC DES PROPRIÉTÉS ANTIVIEILLISSEMENT, ANTI-INFLAMMATOIRE ET DE TEINTE RÉGULIÈRE DE LA PEAU
  申请人：EDISON PHARMACEUTICALS INC

  公开号：WO2010014361A1

  公开（公告）日：2010-02-04

  The present invention relates to methods and compositions comprising naphthoquinones such as 2,3-dimethylnaphthalene-1,4-dione, for the use of treating, regulating or preventing a skin condition characterized by oxidative stress or a degenerative process. Methods of preventing, lightening or reducing the appearance of visible and/or tactile discontinuities of the skin resulting from skin pigmentation or skin aging are also disclosed.