4-octoxy-2,6-pyridinedimethanol | 98828-71-8

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 4-octoxy-2,6-pyridinedimethanol
• 英文别名: [4-(Octyloxy)pyridine-2,6-diyl]dimethanol；[6-(hydroxymethyl)-4-octoxypyridin-2-yl]methanol
• CAS: 98828-71-8
• 化学式: C₁₅H₂₅NO₃
• 分子量: 267.368
• InChiKey: FCRVQBJILPANBV-UHFFFAOYSA-N

物化性质

• 沸点：
  422.2±40.0 °C(Predicted)
• 密度：
  1.070±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  19
• 可旋转键数：
  10
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  62.6
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  4-octoxy-2,6-pyridinedimethanol 在 草酰氯 、 二甲基亚砜 作用下， 以 甲醇 、 二氯甲烷 、 乙腈 为溶剂， 反应 7.0h， 生成
  参考文献：
  名称：

  Multi-responsive coordination polymers utilising metal-stabilised, dynamic covalent imine bonds

  摘要：

  将动态亚胺键纳入配位聚合物中，可以得到稳定的聚合物，对一系列刺激具有敏感性。

  DOI：

  10.1039/c6cc00500d
• 作为产物：
  描述：

  4-氧代-1,4-二氢-2,6-吡啶二甲酸 在 sodium tetrahydroborate 、 硫酸 、 potassium carbonate 作用下， 以 四氢呋喃 、 甲醇 、 N,N-二甲基甲酰胺 为溶剂， 反应 28.0h， 生成 4-octoxy-2,6-pyridinedimethanol
  参考文献：
  名称：

  Synthesis and spectroscopy of anionic tridentate benzimidazole-pyridine carboxylate and tetrazolate chromophore ligands

  摘要：

  We report on seven new anionic benzimidazole-pyridine carboxylate and tetrazolate tridentate (NNO)-N-boolean AND-O-boolean AND and (NNN)-N-boolean AND-N-boolean AND ligands that are modified with chromophore (phenyl, biphenyl, naphthyl) and solubilizing groups. The ligands are UV chromophores with the lowest-energy absorption maxima at 312-335 nm and with the molar absorption coefficients of (20-25) x 10(3) M-1 cm(-1) in DMSO solution. The ligands form neutral complexes with trivalent lanthanides and sensitize the red luminescence of europium. The triplet state energies of the deprotonated ligands, which were measured from the phosphorescence spectra of their lanthanum complexes at 77 K, are in the range of (18.8-21.1) x 10(3) cm(-1). We also describe synthesis of non-symmetric pyridines that are 2,6- and 2,4,6-substituted with hydroxymethyl, carboxaldehyde, and carbonitrile groups. (C) 2014 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.ica.2014.11.037

文献信息

• New proton-ionizable macrocyclic ligands. Synthesis, basicity, reactions, and structures of two aza crown ethers containing the 4-hydroxypyridine unit
  作者：Yohji Nakatsuji、Jerald S. Bradshaw、Pui-Kwan Tse、Giuseppi Arena、Bruce E. Wilson、N. Kent Dalley、Reed M. Izatt

  DOI：10.1039/c39850000749

  日期：——

  Two new reactive aza crown ethers, (1) and (2), containing the 4-hydroxypyridine unit have been prepared and found to be different with respect to pK(H2O) values for H2L+, structures of the hydrates of HL, and complex formation with benzylamine and the benzylammonium ion.

  制备了两种含有4-羟基吡啶单元的新的反应性氮杂冠氮醚（1）和（2），发现它们在水合物结构的H 2 L +的p K（H 2 O）值方面不同。HL，并与苄胺和苄基铵离子形成络合物。
• Bradshaw, Jerald S.; Nakatsuji, Yohji; Huszthy, Peter, Journal of Heterocyclic Chemistry, 1986, vol. 23, p. 353 - 360
  作者：Bradshaw, Jerald S.、Nakatsuji, Yohji、Huszthy, Peter、Wilson, Bruce E.、Dalley, N. Kent、Izatt, Reed M.

  DOI：——

  日期：——
• NAKATSUJI, YOHJI;BRADSHAW, J. S.;TSE, PUI-KWAN;ARENA, G.;WILSON, B. E.;DA+, J. CHEM. SOC. CHEM. COMMUN., 1985, N 12, 749-751
  作者：NAKATSUJI, YOHJI、BRADSHAW, J. S.、TSE, PUI-KWAN、ARENA, G.、WILSON, B. E.、DA+

  DOI：——

  日期：——
• Synthesis and spectroscopy of anionic tridentate benzimidazole-pyridine carboxylate and tetrazolate chromophore ligands
  作者：Nail M. Shavaleev、Svetlana V. Eliseeva

  DOI：10.1016/j.ica.2014.11.037

  日期：2015.3

  We report on seven new anionic benzimidazole-pyridine carboxylate and tetrazolate tridentate (NNO)-N-boolean AND-O-boolean AND and (NNN)-N-boolean AND-N-boolean AND ligands that are modified with chromophore (phenyl, biphenyl, naphthyl) and solubilizing groups. The ligands are UV chromophores with the lowest-energy absorption maxima at 312-335 nm and with the molar absorption coefficients of (20-25) x 10(3) M-1 cm(-1) in DMSO solution. The ligands form neutral complexes with trivalent lanthanides and sensitize the red luminescence of europium. The triplet state energies of the deprotonated ligands, which were measured from the phosphorescence spectra of their lanthanum complexes at 77 K, are in the range of (18.8-21.1) x 10(3) cm(-1). We also describe synthesis of non-symmetric pyridines that are 2,6- and 2,4,6-substituted with hydroxymethyl, carboxaldehyde, and carbonitrile groups. (C) 2014 Elsevier B.V. All rights reserved.
• Multi-responsive coordination polymers utilising metal-stabilised, dynamic covalent imine bonds
  作者：Fátima García、Janis Pelss、Han Zuilhof、Maarten M. J. Smulders

  DOI：10.1039/c6cc00500d

  日期：——

  Incorporation of dynamic imine bonds into coordination polymers yields stable polymers that are sensitive to a range of stimuli.

  将动态亚胺键纳入配位聚合物中，可以得到稳定的聚合物，对一系列刺激具有敏感性。