2-羟基-4-甲基-3-戊酮 | 52279-27-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 2-羟基-4-甲基-3-戊酮
• 英文名称: 4-methyl-2-hydroxypentanone
• 英文别名: 2-hydroxy-4-methyl-pentan-3-one；2-Hydroxy-4-methyl-pentan-3-on；2-Hydroxy-4-methyl-pentanon-(3)；4-Methyl-3-pentanon-2-ol；2-Hydroxy-4-methylpentan-3-one
• CAS: 52279-27-3
• 化学式: C₆H₁₂O₂
• 分子量: 116.16
• InChiKey: JZFRZJUXMOAVFU-UHFFFAOYSA-N

物化性质

• 熔点：
  72-73 °C
• 沸点：
  47-48 °C(Press: 9.5 Torr)
• 密度：
  0.944±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  8
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2-羟基-4-甲基-3-戊酮 在 吡啶 、 氯化亚砜 作用下， 以 苯 为溶剂， 生成 2-chlor-4-methyl-3-pentanon
  参考文献：
  名称：

  Asinger,F. et al., Justus Liebigs Annalen der Chemie, 1960, vol. 634, p. 164 - 184

  摘要：

  DOI：
• 作为产物：
  描述：

  异丙基溴化镁 、 乳腈 在 乙醚 作用下， 生成 2-羟基-4-甲基-3-戊酮
  参考文献：
  名称：

  Braude; Evans, Journal of the Chemical Society, 1956, p. 3238

  摘要：

  DOI：

文献信息

• Stereoselective reduction of α-hydroxy ketones
  作者：Tadashi Nakata、Tadasu Tanaka、Takeshi Oishi

  DOI：10.1016/s0040-4039(00)87969-1

  日期：1983.1

  Reduction of α-hydroxy ketones with zinc horohydride afforded the -glycols in high stereoselectivity, while reduction of their α-(t-butyldiphenylsily)oxy derivatives with sodium bis(2-methoxyethoxy)aluminum hydride gave the isomeric . The structure-stereoselectivity relationship has been discussed.

  用卤化锌还原α-羟基酮得到高立体选择性的-二醇，而用双（2-甲氧基乙氧基）氢化铝钠还原其α-（叔丁基二苯基甲硅烷基）氧基衍生物得到异构体。已经讨论了结构-立体选择性关系。
• ERK INHIBITORS AND USES THEREOF
  申请人：Celgene Avilomics Research, Inc.

  公开号：US20140228322A1

  公开（公告）日：2014-08-14

  The present invention provides compounds, compositions thereof, and methods of using the same.

  本发明提供了化合物、其组合物以及使用它们的方法。
• Compositions and Methods for Fermentation of Biomass
  申请人：Parekh Sarad

  公开号：US20100268000A1

  公开（公告）日：2010-10-21

  In one aspect, this invention relates to production of useful fermentation end-products from biomass through simultaneous hydrolysis and fermentation by a microorganism, such as Clostridium phytofermentans . The invention also relates to the development of a process for efficient pretreatment and conversion of lignocellulosic biomass to end-products with high conversion efficiency (yield). In another aspect, methods for producing a fermentation end-product by fermenting hexose (C6) and pentose (C5) sugars with a microorganism, such as Clostridium phytofermentans are disclosed herein.

  在一个方面，这项发明涉及通过微生物（如植物发酵槽菌）的同时水解和发酵，从生物质中生产有用的发酵终产物。该发明还涉及开发一种高效预处理和转化木质纤维素生物质为高转化效率（产率）的终产物的过程。在另一个方面，本文介绍了利用微生物（如植物发酵槽菌）发酵己糖（C6）和戊糖（C5）糖产生发酵终产物的方法。
• BIOFUEL PRODUCTION
  申请人：Yoshikuni Yasuo

  公开号：US20090139134A1

  公开（公告）日：2009-06-04

  Methods, enzymes, recombinant microorganism, and microbial systems are provided for converting polysaccharides, such as those derived from biomass, into suitable monosaccharides or oligosaccharides, as well as for converting suitable monosaccharides or oligosaccharides into commodity chemicals, such as biofuels. Commodity chemicals produced by the methods described herein are also provided. Commodity chemical enriched, refinery-produced petroleum products are also provided, as well as methods for producing the same.

  提供了用于将多糖转化为适当的单糖或寡糖的方法、酶、重组微生物和微生物系统，例如从生物质中提取的多糖。同时提供了将适当的单糖或寡糖转化为商品化学品，如生物燃料的方法。本文描述的方法生产的商品化学品也提供了。此外，还提供了商品化学品富集的、精炼生产的石油产品，以及生产这些产品的方法。
• [EN] ACYL RIBONUCLEOSIDES AND ACYL DEOXYRIBONUCLEOSIDES<br/>[FR] RIBONUCLEOSIDES D'ACYLE ET DESOXYRIBONUCLEOSIDES D'ACYLE
  申请人：COGNIS IP MAN GMBH

  公开号：WO2005049633A1

  公开（公告）日：2005-06-02

  The present invention is concerned with acyl ribonucleosides and with acyl deoxyribonucleosides. It is furthermore concerned with an enzymatic process for the manufacture of acyl ribonucleosides and of acyl deoxyribonucleosides. It is furthermore concerned with the use of acyl ribonucleosides and of acyl deoxyribonucleosides for cosmetic and for pharmaceutical purposes and with their use as a food supplement for humans or animals. It is furthermore concerned with compositions containing acyl ribonucleosides and acyl deoxyribonucleosides, whereby these compositions are suitable for cosmetic or for pharmaceutical purposes or as food supplement.

  本发明涉及酰基核糖核苷和酰基脱氧核糖核苷。此外，本发明还涉及一种用于制造酰基核糖核苷和酰基脱氧核糖核苷的酶法过程。此外，本发明还涉及酰基核糖核苷和酰基脱氧核糖核苷在化妆品和药品中的用途，以及它们作为人类或动物的食品补充剂的用途。此外，本发明还涉及含有酰基核糖核苷和酰基脱氧核糖核苷的组合物，这些组合物适用于化妆品或药品或作为食品补充剂。