(S)-3-Isopropyl-5,6-dioxo-heptanal | 733744-33-7

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (S)-3-Isopropyl-5,6-dioxo-heptanal
• 英文别名: (3S)-5,6-dioxo-3-propan-2-ylheptanal
• CAS: 733744-33-7
• 化学式: C₁₀H₁₆O₃
• 分子量: 184.235
• InChiKey: UWRZUXDSAZGWNX-VIFPVBQESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  13
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.7
• 拓扑面积：
  51.2
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  (S)-3-Isopropyl-5,6-dioxo-heptanal 在 sodium periodate 作用下， 以 甲醇 为溶剂， 反应 4.0h， 生成 (3S)-3-isopropyl-5-oxopentanoic acid
  参考文献：
  名称：

  Studies towards the total synthesis of contignasterol

  摘要：

  The (17R,20S,22S,24S) C-20-C-29 segment of contignasterol has been stereoselectively prepared in 8 steps and 40% overall yield from (S)-carvone. Synthetic studies towards contignasterol's C/D ring functionalization/isomerization are also reported. (C) 2004 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2004.04.083
• 作为产物：
  描述：

  右旋香芹酮 在 platinum(IV) oxide 氢气 、 臭氧 作用下， 以 甲醇 为溶剂， 反应 4.0h， 生成 (S)-3-Isopropyl-5,6-dioxo-heptanal
  参考文献：
  名称：

  Studies towards the total synthesis of contignasterol

  摘要：

  The (17R,20S,22S,24S) C-20-C-29 segment of contignasterol has been stereoselectively prepared in 8 steps and 40% overall yield from (S)-carvone. Synthetic studies towards contignasterol's C/D ring functionalization/isomerization are also reported. (C) 2004 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2004.04.083

文献信息

• Studies towards the total synthesis of contignasterol
  作者：Irene Izzo、Carmela Della Monica、Giuseppe Bifulco、Francesco De Riccardis

  DOI：10.1016/j.tet.2004.04.083

  日期：2004.6

  The (17R,20S,22S,24S) C-20-C-29 segment of contignasterol has been stereoselectively prepared in 8 steps and 40% overall yield from (S)-carvone. Synthetic studies towards contignasterol's C/D ring functionalization/isomerization are also reported. (C) 2004 Elsevier Ltd. All rights reserved.