trans-Phytensaeure-methylester | 13853-15-1

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: trans-Phytensaeure-methylester
• 英文别名: Methylphytenoat；Methyl 3,7,11,15-tetramethylhexadec-2-enoate；methyl (E)-3,7,11,15-tetramethylhexadec-2-enoate
• CAS: 13853-15-1；13853-16-2；64433-35-8
• 化学式: C₂₁H₄₀O₂
• 分子量: 324.547
• InChiKey: WISPDDYDWJMVMK-CAPFRKAQSA-N

物化性质

• 熔点：
  149-152 °C
• 沸点：
  390.2±11.0 °C(Predicted)
• 密度：
  0.869±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)
• 保留指数：
  2185.8

计算性质

• 辛醇/水分配系数(LogP)：
  8.7
• 重原子数：
  23
• 可旋转键数：
  14
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• LOW-VISCOSITY LIQUID CRYSTAL COMPOUND
  申请人：Ikeda Yutaka

  公开号：US20120264923A1

  公开（公告）日：2012-10-18

  The present invention relates to a liquid crystal compound that can be used as a base for injection formulations. The present invention provides an amphipathic compound having the following general formula (I): wherein X and Y each denotes a hydrogen atom or together denote an oxygen atom, n denotes an integer from 0 to 2, m denotes the integer 1 or 2, and R denotes a hydrophilic group generated by removal of one hydroxyl group from any one selected from the group consisting of glycerol, erythritol, pentaerythritol, diglycerol, triglycerol, xylose, sorbitol, ascorbic acid, glucose, galactose, mannose, dipentaerythritol, maltose, mannitol, and xylitol; as well as a base for injection formulations and depot formulation comprising the same.

  本发明涉及一种可作为注射制剂基质的液晶化合物。本发明提供了一种两亲性化合物，具有如下通式(I)： 其中，X和Y各自表示氢原子，或者共同表示一个氧原子，n表示从0到2的整数，m表示整数1或2，R表示由来自甘油、赤藓糖醇、季戊四醇、双甘油、三甘油、木糖、山梨糖醇、抗坏血酸、葡萄糖、半乳糖、甘露糖、双季戊四醇、麦芽糖、甘露醇和木糖醇中任选其一去除一个羟基而生成的亲水基团；以及包含该化合物的注射制剂基质和储存型制剂。
• ADHESION PREVENTING AGENT
  申请人：FARNEX INCORPORATED

  公开号：US20160067208A1

  公开（公告）日：2016-03-10

  The present invention relates to an adhesion preventing agent comprising an amphipathic compound having the following general formula (I): wherein X and Y each denotes a hydrogen atom or together denote an oxygen atom, n denotes an integer from 0 to 2, m denotes the integer 1 or 2, AA: AA denotes a single bond or double bond, and R denotes a hydrophilic group having two or more hydroxyl groups.

  本发明涉及一种防粘剂，包括具有以下通式（I）的两亲化合物： 其中，X和Y各自表示氢原子，或者共同表示一个氧原子，n表示从0到2的整数，m表示1或2的整数，AA:AA表示单键或双键，而R表示具有两个或更多羟基的亲水基团。
• LOW-VISCOSITY LIQUID-CRYSTAL COMPOUND
  申请人：ChemGenesis Incorporated

  公开号：EP2518040A1

  公开（公告）日：2012-10-31

  The present invention relates to a liquid crystal compound that can be used as a base for injection formulations. The present invention provides an amphipathic compound having the following general formula (I): wherein X and Y each denotes a hydrogen atom or together denote an oxygen atom, n denotes an integer from 0 to 2, m denotes the integer 1 or 2, and R denotes a hydrophilic group generated by removal of one hydroxyl group from any one selected from the group consisting of glycerol, erythritol, pentaerythritol, diglycerol, triglycerol, xylose, sorbitol, ascorbic acid, glucose, galactose, mannose, dipentaerythritol, maltose, mannitol, and xylitol; as well as a base for injection formulations and depot formulation comprising the same.

  本发明涉及一种可用作注射制剂基质的液晶化合物。本发明提供了一种具有以下通式（I）的两性化合物： 赤藓糖醇、季戊四醇、二甘油、甘油三酯、木糖、山梨醇、抗坏血酸、葡萄糖、半乳糖、甘露糖、二季戊四醇、麦芽糖、甘露糖醇和木糖醇；以及包含这些成分的注射剂和药剂的基质。
• HIGHLY SAFE NON-LAMELLAR LIQUID CRYSTAL FORMING COMPOSITION
  申请人：Farnex Incorporated

  公开号：EP4098281A1

  公开（公告）日：2022-12-07

  The present invention provides a highly safe non-lamellar liquid crystal-forming composition. The present invention relates to a non-lamellar liquid crystal-forming composition comprising a phospholipid and an amphipathic compound represented by the following general formula (I), wherein X and Y each denotes a hydrogen atom or together denote an oxygen atom, n denotes the integer 1 or 2, m denotes the integer 1 or 2, and R denotes a hydrophilic group having one or more hydroxyl groups, and wherein the composition has an increased biocompatibility by the phospholipid.

  本发明提供了一种高度安全的非胶束液晶形成组合物。本发明涉及一种非胶束状液晶形成组合物，该组合物由磷脂和由以下通式（I）表示的两性化合物组成，其中 X 和 Y 各自表示氢原子或共同表示氧原子，n 表示整数 1 或 2，m 表示整数 1 或 2，R 表示具有一个或多个羟基的亲水基团，并且该组合物通过磷脂提高了生物相容性。
• EP2992910A1
  申请人：——

  公开号：EP2992910A1

  公开（公告）日：2016-03-09