2-(benzo[d]thiazole-2-carbonyl)benzonitrile | 1632132-62-7

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-(benzo[d]thiazole-2-carbonyl)benzonitrile
• 英文别名: 2-(1,3-Benzothiazole-2-carbonyl)benzonitrile；2-(1,3-benzothiazole-2-carbonyl)benzonitrile
• CAS: 1632132-62-7
• 化学式: C₁₅H₈N₂OS
• 分子量: 264.307
• InChiKey: MAQIPLJNVGSMLT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  19
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  82
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  1,1-二溴-2-(邻氰基苯基)乙烯 、 双(2-氨基苯基)二硫 在 copper(II) bis(trifluoromethanesulfonate) 、 caesium carbonate 作用下， 以 二甲基亚砜 为溶剂， 反应 20.0h， 以48%的产率得到2-(benzo[d]thiazole-2-carbonyl)benzonitrile
  参考文献：
  名称：

  Synthesis of 2-Acylbenzothiazoles via the Cu(OTf)2-Catalyzed Tandem Reaction of β,β-Dihalidestyrenes with 2,2′-Disulfanediyldianilines

  摘要：

  A new method has been developed for the one-pot construction of 2-acylbenzothiazoles via the Cu(OTf)(2)-catalyzed tandem reaction of ,-dihalidestyrenes with 2,2-disulfane-diyldianilines. A variety of different dihalidestyrenes and diphenyldisulfanes were efficiently converted into the corresponding 2-acylbenzothiszole derivatives in the presence of Cu(OTf)(2). Most importantly, this protocol allowed for the long chain 1,1-dibromohept-1-ene to be converted into the corresponding 2-hexylbenzo[d]thiazole in moderate yield.

  DOI：

  10.1055/s-0033-1340288

文献信息

• Synthesis of 2-Acylbenzothiazoles via the Cu(OTf)2-Catalyzed Tandem Reaction of β,β-Dihalidestyrenes with 2,2′-Disulfanediyldianilines
  作者：Chen-Liang Deng、Zeng-Le Zhou、Tao Fang、Ri-Yuan Tang、Xing-Guo Zhang

  DOI：10.1055/s-0033-1340288

  日期：——

  A new method has been developed for the one-pot construction of 2-acylbenzothiazoles via the Cu(OTf)(2)-catalyzed tandem reaction of ,-dihalidestyrenes with 2,2-disulfane-diyldianilines. A variety of different dihalidestyrenes and diphenyldisulfanes were efficiently converted into the corresponding 2-acylbenzothiszole derivatives in the presence of Cu(OTf)(2). Most importantly, this protocol allowed for the long chain 1,1-dibromohept-1-ene to be converted into the corresponding 2-hexylbenzo[d]thiazole in moderate yield.