(Z)-3,4-bis(pentamethylphenyl)hex-3-ene | 489459-90-7

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: (Z)-3,4-bis(pentamethylphenyl)hex-3-ene
• 英文别名: 3,4-bis(pentamethylphenyl)hex-3-ene；bis(pentamethylphenyl)hex-3-ene；1,2,3,4,5-pentamethyl-6-[(Z)-4-(2,3,4,5,6-pentamethylphenyl)hex-3-en-3-yl]benzene
• CAS: 489459-90-7
• 化学式: C₂₈H₄₀
• 分子量: 376.626
• InChiKey: IHZBGUCYIVVWRP-QPLCGJKRSA-N

物化性质

• 熔点：
  175-177 °C
• 沸点：
  484.3±40.0 °C(Predicted)
• 密度：
  0.922±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  9.9
• 重原子数：
  28
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  (Z)-3,4-bis(pentamethylphenyl)hex-3-ene 在 nitric oxide 作用下， 以 二氯甲烷 为溶剂， 生成
  参考文献：
  名称：

  Novel Arene Receptors as Nitric Oxide (NO) Sensors

  摘要：

  Nitric oxide sensors are based on the reversible, specific, and efficient binding to various types of arene receptors via intermolecular complexes, which are characterized by complete electron delocalization and strong interaction between the donor and acceptor moieties.

  DOI：

  10.1021/ja020217o
• 作为产物：
  描述：

  在 nitric oxide 作用下， 以 二氯甲烷 为溶剂， 生成 (Z)-3,4-bis(pentamethylphenyl)hex-3-ene
  参考文献：
  名称：

  Novel Arene Receptors as Nitric Oxide (NO) Sensors

  摘要：

  Nitric oxide sensors are based on the reversible, specific, and efficient binding to various types of arene receptors via intermolecular complexes, which are characterized by complete electron delocalization and strong interaction between the donor and acceptor moieties.

  DOI：

  10.1021/ja020217o

文献信息

• A Remarkably Efficient Synthesis of Pure <i>cis</i>-Stilbenoid Hydrocarbons Using <i>trans</i>-Dibromoalkenes via Palladium Catalysis
  作者：Rajendra Rathore、Mihaela I. Deselnicu、Carrie L. Burns

  DOI：10.1021/ja027421w

  日期：2002.12.1

  A remarkably versatile synthesis of cis-stilbenoid hydrocarbons containing highly functionalized phenyl groups is developed via an efficient palladium-catalyzed coupling of aryl Grignard reagents with trans-1,2-dibromoalkenes (generally obtained via bromination of the corresponding dialkylacetylenes) in tetrahydrofuran.

  通过芳基格氏试剂与反式-1,2-二溴烯烃（通常通过相应的二烷基乙炔的溴化反应获得）在四氢呋喃中的有效钯催化偶联，开发了一种非常通用的含有高度官能化苯基的顺式芪类烃的合成方法。
• Two Palladium-Catalyzed Domino Reactions from One Set of Substrates/Reagents:  Efficient Synthesis of Substituted Indenes and <i>cis</i>-Stilbenoid Hydrocarbons from the Same Internal Alkynes and Hindered Grignard Reagents
  作者：Cheng-Guo Dong、Pik Yeung、Qiao-Sheng Hu

  DOI：10.1021/ol062885a

  日期：2007.1.1

  Two types of domino reactions from the same internal alkynes and hindered Grignard reagents based on carbopalladation, Pd-catalyzed cross-coupling reaction, and a C-H activation strategy are described. The realization of these domino reactions relied on the control of the use of the ligand and the reaction temperature. Our study provides efficient access to useful polysubstituted indenes and cis-substituted

  描述了两种基于相同内部炔烃和受阻格氏试剂基于卡巴巴拉定的多米诺骨牌反应，Pd催化的交叉偶联反应和CH活化策略。这些多米诺反应的实现依赖于对配体的使用和反应温度的控制。我们的研究提供了有效的途径来获得有用的多取代的茚基和顺式取代的对苯二酚，并可能以更有效的方式提供一种发展串联/多米诺反应的新方法。[反应：请参见文字]。
• Synthesis of Substituted Indenes and<i>cis</i>-Stilbenoid Hydrocarbons via Palladium-Catalyzed Domino Reactions of Hindered Grignard Reagents with (<i>E</i>)-1,2-Dibromoethenes
  作者：Qiao-Sheng Hu、Cheng-Guo Dong、Tao-Ping Liu

  DOI：10.1055/s-2008-1067195

  日期：2008.8

  Palladium-catalyzed domino reactions of (E)-1,2-dibromoethenes with hindered Grignard reagents based on carbopalladation, palladium-catalyzed cross-coupling, and C-H activation are described. These domino reactions could be influenced by the ligand, reaction temperature, nucleophilicity of Grignard reagents, and steric hindrance of the substrates. Our study provides an efficient access to some useful

  描述了基于碳钯化、钯催化交叉偶联和 CH 活化的 (E)-1,2-二溴乙烯与受阻格氏试剂的钯催化多米诺反应。这些多米诺反应可能受到配体、反应温度、格氏试剂的亲核性和底物的空间位阻的影响。我们的研究提供了对一些有用的多取代茚和顺式取代茋的有效途径，并且可能有助于开发其他交叉偶联和基于 CH 活化的串联/多米诺反应。