(+/-)-ε-fenchene | 512-50-5

• 分子结构分类: 有机化合物 - 碳氢化合物 - 不饱和烃
• 英文名称: (+/-)-ε-fenchene
• 英文别名: (+/-)-ε-Fenchen；(1R,4S)-1,2,3-trimethylbicyclo[2.2.1]hept-2-ene
• CAS: 512-50-5
• 化学式: C₁₀H₁₆
• 分子量: 136.237
• InChiKey: HIZBWIXMAQEVLW-VHSXEESVSA-N

物化性质

• 沸点：
  159.5±7.0 °C(Predicted)
• 密度：
  0.912±0.06 g/cm3(Predicted)
• LogP：
  4.101 (est)

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  10
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  过氧化氢苯甲酰 、 氯仿 、 (+/-)-ε-fenchene 生成 alkaline earth salt of/the/ methylsulfuric acid
  参考文献：
  名称：

  Komppa; Nyman, Chemische Berichte, 1939, vol. 72, p. 16,17

  摘要：

  DOI：
• 作为产物：
  描述：

  1,3,3-三甲基三环[2.2.1.02,6]庚烷 在 Fuller's Earth 作用下， 生成 (+/-)-ε-fenchene
  参考文献：
  名称：

  E VALUATION OF AN E LECTRONIC E SOPHAGEAL D ETECTOR D EVICE IN P ATIENTS WITH M ORBID O BESITY AND P ULMONARY F AILURE

  摘要：

  Objective: Undetected esophageal intubation can result in permanent injury or death. Clinical confirmation of tube location may be misleading. Adjunctive methods should be used to supplement clinical judgment. Unfortunately, end-tidal carbon dioxide may misidentify properly placed tracheal tubes in low perfusion situations, while esophageal detector devices (EDDs) may misidentify properly placed tracheal tubes in situations where little airway dead space exists (morbid obesity, pulmonary failure). This study evaluated a modified EDD (the electronic esophageal detector device, or EEDD) designed to eliminate the problem of misidentified tracheal intubations. Methods: Intubated morbidly obese or pulmonary failure patients were eligible for study entry. All endotracheal tubes (ETTs) were confirmed to be tracheal by waveform capnography and clinical judgment prior to study entry. Following consent, all patients were attached to the EEDD and a "measurement" was made to determine the "location" of their ETTs. Probability of misidentifying a tracheal intubation in these high-risk populations was calculated using a log-normal distribution method. Results: Twenty-seven morbidly obese patients and 37 pulmonary failure patients were entered. The EEDD correctly identified all tracheal intubations in these patients, giving a false-negative rate of zero. The probability of misidentifying a tracheal intubation in the combined group was 0.06%. Conclusion: This study demonstrates that the EEDD reliably identifies tracheal intubations in situations where standard EDDs may fail. However, future studies must determine the reliability of this device for identification of esophageal intubations and the reliability of this device in the less controlled emergency department and prehospital settings.

  DOI：

  10.1080/10903120290938805

文献信息

• Komppa; Nyman, Justus Liebigs Annalen der Chemie, 1935, vol. 517, p. 105,117
  作者：Komppa、Nyman

  DOI：——

  日期：——
• Komppa; Nyman, Chemische Berichte, 1936, vol. 69, p. 334,339
  作者：Komppa、Nyman

  DOI：——

  日期：——
• Komppa; Nyman, Justus Liebigs Annalen der Chemie, 1940, vol. 543, p. 111,114, 117
  作者：Komppa、Nyman

  DOI：——

  日期：——
• M ANAGING THE P OST - RESUSCITATION P ATIENT IN THE F IELD
  作者：David E. Persse、Brian S. Zachariah、Jane G. Wigginton

  DOI：10.1080/10903120290938922

  日期：2002.1

  The principal goal after successful resuscitation of a cardiac arrest patient is to maintain the patient's pulse and avoid a pulseless state. Of equal importance in the post-resuscitation patient are efforts to prevent myocardial dysfunction and increase the likelihood of a good neurologic outcome. To optimize cardiac and hemodynamic resuscitation, paramedics should obtain good background information, which could provide clues to factors contributing to the cardiac arrest, such as the use of certain drugs or being overdue for dialysis, and could aid in customizing therapy for rhythm disturbances and hemodynamic aberrations. Treatment of rhythm disturbances depends on the type of arrhythmia identified, the history of present illness, and the resuscitation efforts provided. Common post-resuscitation dysrhythmias are wide-complex tachycardia, narrow-complex tachycardia, and bradycardia. Optimizing neurologic resuscitation is difficult, but evidence suggests that hypertensive reperfusion, hemodilution, and mild hypothermia may be of benefit in improving neurologic outcome after resuscitation. Unfortunately, to date, no proven therapies are available to improve neurologic outcome after resuscitation from cardiac arrest.
• Toivonen; Veijola; Friberg, Suomen Kemistilehti B, 1935, vol. 8, p. 44
  作者：Toivonen、Veijola、Friberg

  DOI：——

  日期：——