3-(4-羟基-3,5-二甲氧基苯基)-1,2-丙二醇 | 22805-15-8

• 物质功能分类: 天然产物 - 苯丙素
• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 中文名称: 3-(4-羟基-3,5-二甲氧基苯基)-1,2-丙二醇
• 英文名称: 3-(4-hydroxy-3,5-dimethoxyphenyl) propane-1,2-diol
• 英文别名: 3-(4-hydroxy-3,5-dimethoxyphenyl)-1,2-propanediol；3-(4-Hydroxy-3,5-dimethoxyphenyl)propane-1,2-diol；3-(4-hydroxy-3,5-dimethoxyphenyl)propane-1,2-diol
• CAS: 22805-15-8
• 化学式: C₁₁H₁₆O₅
• 分子量: 228.245
• InChiKey: IMVVRJZYFJNFBX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  16
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  79.2
• 氢给体数：
  3
• 氢受体数：
  5

安全信息

• 海关编码：
  2909499000

反应信息

• 作为产物：
  描述：

  4-烯丙基-2,6-二甲氧基苯酚 在 palladium 10% on activated carbon 、 AD-mix β 、 氢气 、 potassium carbonate 作用下， 以 乙醇 、 水 、 N,N-二甲基甲酰胺 、 叔丁醇 为溶剂， 20.0 ℃ 、100.0 kPa 条件下， 反应 48.0h， 生成 3-(4-羟基-3,5-二甲氧基苯基)-1,2-丙二醇
  参考文献：
  名称：

  [EN] NOVEL 1-PHENYLMONO- OR -POLYHYDROXYPROPANE COMPOUNDS, COMPOSITIONS AND COSMETIC USES THEREOF
  [FR] NOUVEAUX COMPOSÉS 1-PHÉNYLMONO- OU -POLYHYDROXYPROPANE COMPOSÉS, COMPOSITIONS ET LEURS UTILISATIONS COSMÉTIQUES

  摘要：

  本发明涉及公式（I）的新化合物，以及包含它们的组合物，还涉及将其用于预防和/或美容治疗皮肤老化迹象的用途。

  公开号：

  WO2016092074A1

文献信息

• [EN] SULFAMIDE SODIUM CHANNEL INHIBITORS<br/>[FR] INHIBITEURS SULFAMIDES DES CANAUX DE SODIUM
  申请人：AMGEN INC

  公开号：WO2013134518A1

  公开（公告）日：2013-09-12

  The present invention provides compounds of Formula I, or pharmaceutically acceptable salts thereof, that are inhibitors of voltage-gated sodium channels, in particular Nav 1.7. The compounds are useful for the treatment of diseases treatable by inhibition of sodium channels such as pain disorders. Also provided are pharmaceutical compositions containing compounds of the present invention.

  本发明提供了式I的化合物或其药学上可接受的盐，这些化合物是电压门控钠通道的抑制剂，特别是Nav 1.7。这些化合物对于治疗通过抑制钠通道可治疗的疾病，如疼痛障碍，是有用的。还提供了含有本发明化合物的药物组合物。
• 1-phenylmono- or -polyhydroxypropane compounds, compositions and cosmetic uses thereof
  申请人：L'OREAL

  公开号：US10307353B2

  公开（公告）日：2019-06-04

  The present invention relates to novel compounds of formula (I) to compositions comprising same, and also to the use thereof for preventing and/or cosmetically treating the signs of aging of the skin.

  本发明涉及式 (I) 的新型化合物 以及将其用于预防和/或美容治疗皮肤衰老迹象的用途。
• METHOD FOR TIERED PRODUCTION OF BIOBASED CHEMICALS AND BIOFUELS FROM LIGNIN
  申请人：Peterson John R.

  公开号：US20130232852A1

  公开（公告）日：2013-09-12

  The present invention is directed generally to a method of production of value-added, biobased chemicals from lignin sources, including waste lignin. A method of using a depolymerization of lignin to create a tiered production of biobased aromatic chemicals and biofuels is also described herein. The method described herein may also allow for the selective production of the biobased aromatic chemicals and biofuels. Additionally, a reduction of waste products may also be provided from the present method.
• NOVEL 1-PHENYLMONO- OR -POLYHYDROXYPROPANE COMPOUNDS, COMPOSITIONS AND COSMETIC USES THEREOF
  申请人：L'OREAL

  公开号：US20170360665A1

  公开（公告）日：2017-12-21

  The present invention relates to novel compounds of formula (I) to compositions comprising same, and also to the use thereof for preventing and/or cosmetically treating the signs of aging of the skin.
• [EN] A METHOD FOR TIERED PRODUCTION OF BIOBASED CHEMICALS AND BIOFUELS FROM LIGNIN<br/>[FR] PROCÉDÉ DE PRODUCTION ÉTAGÉE DE BIOPRODUITS CHIMIQUES ET DE BIOCOMBUSTIBLES À PARTIR DE LIGNINE
  申请人：VERTICHEM CORP

  公开号：WO2013134756A1

  公开（公告）日：2013-09-12

  The present invention is directed generally to a method of production of value-added, biobased chemicals from lignin sources, including waste lignin. A method of using a depolymerization of lignin to create a tiered production of biobased aromatic chemicals and biofuels is also described herein. The method described herein may also allow for the selective production of the biobased aromatic chemicals and biofuels. Additionally, a reduction of waste products may also be provided from the present method.