3-(L-薄荷氧基)-2-甲基-1,2-丙二醇 | 195863-84-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 中文名称: 3-(L-薄荷氧基)-2-甲基-1,2-丙二醇
• 英文名称: 3-(L-Menthoxy)-2-methylpropane-1,2-diol
• 英文别名: 2-methyl-3-[(1R,2S,5R)-5-methyl-2-propan-2-ylcyclohexyl]oxypropane-1,2-diol
• CAS: 195863-84-4
• 化学式: C₁₄H₂₈O₃
• 分子量: 244.37
• InChiKey: XCNCWOPROFTLGU-RBKKPWLPSA-N

物化性质

• 沸点：
  371.5±22.0 °C(Predicted)
• 密度：
  0.99
• LogP：
  3.38
• 物理描述：
  Colourless liquid; minty, cool aroma
• 溶解度：
  Soluble in hexane; Slightly soluble in water
• 折光率：
  1.468-1.474

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  17
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  49.7
• 氢给体数：
  2
• 氢受体数：
  3

制备方法与用途

食品添加剂最大允许使用量及最大允许残留量标准

添加剂中文名称	允许使用该种添加剂的食品中文名称	添加剂功能	最大允许使用量（g/kg）	最大允许残留量（g/kg）
3-（l-薄荷氧基）-2-甲基-1，2-丙二醇	食品	食品用香料	用于配制香精的各香料成分不得超过在GB 2760中的最大允许使用量和最大允许残留量

此表列出了特定食品添加剂的相关信息及使用规定。

文献信息

• MIXTURES HAVING IMPROVED COOLING EFFECT
  申请人：SYMRISE AG

  公开号：US20150139918A1

  公开（公告）日：2015-05-21

  A mixtures which contain (a) at least one phenylalkenal of formula (I) wherein R 1 and R 2 independently represent hydrogen, a methyl or phenyl group, R 3 represents hydrogen, a phenyl group, alkenyl group or a linear or branched alkyl group with 1 to 5 carbon atoms, and the broken double lines independently represent a single bond or a double bond, and (b) at least one physiological cooling agent.

  一种混合物，其中包含（a）至少一种式（I）的苯基烯醛，其中R1和R2独立地表示氢，甲基或苯基基团，R3表示氢，苯基，烯基或具有1至5个碳原子的线性或支链烷基基团，而断裂的双键独立地表示单键或双键，以及（b）至少一种生理降温剂。
• Cooling preparations
  申请人：Symrise AG

  公开号：US10182584B2

  公开（公告）日：2019-01-22

  Proposed are preparations, comprising special amides and menthol or menthol compounds or aromatic substances, characterized in that they have improved flavor and scent properties, and also that they allow the production of preparations, particularly emulsions with improved shelf life.

  建议的制剂由特殊酰胺和薄荷醇或薄荷醇化合物或芳香物质组成，其特点是它们具有更好的风味和香味特性，还能生产出保质期更长的制剂，特别是乳剂。
• Coolant mixtures
  申请人：Symrise AG

  公开号：US10933039B2

  公开（公告）日：2021-03-02

  The invention relates to coolant mixtures containing: (a) at least one compound of formula (I), (b) at least one compound of formula (II) in which R1 stands for hydrogen or a methyl group, R2 stands for a methyl, ethyl or propyl group and n stands for 0, 1, or 2, and if applicable (c) an additional component.

  本发明涉及含有以下成分的冷却剂混合物：(a) 至少一种式 (I) 化合物，(b) 至少一种式 (II) 化合物，其中 R1 代表氢或甲基，R2 代表甲基、乙基或丙基，n 代表 0、1 或 2，以及 (c) 附加成分（如适用）。
• Preparations having a cooling effect
  申请人：Symrise AG

  公开号：US11234450B2

  公开（公告）日：2022-02-01

  Proposed are preparations, comprising special amides and menthol or menthol compounds or aromatic substances, characterized in that they have improved flavor and scent properties, and also that they allow the production of preparations, particularly emulsions with improved shelf life.

  建议的制剂由特殊酰胺和薄荷醇或薄荷醇化合物或芳香物质组成，其特点是它们具有更好的风味和香味特性，还能生产出保质期更长的制剂，特别是乳剂。
• SENSATION MODIFYING TOPICAL COMPOSITION FOAM
  申请人：TAMARKIN Dov

  公开号：US20080253973A1

  公开（公告）日：2008-10-16

  This invention relates to foamable compositions that are capable of producing a sensation or sensation modifying effect upon application on a body surface. More particularly the invention relates to foamable pharmaceutical, therapeutic and cosmetic compositions, comprising an active agent, having a sensation or sensation modifying affect on a body surface, upon application. More particularly, the invention relates to foamable compositions comprising: (a) a foamable carrier; (b) at least one sensation or sensation modifying agent, selected from the group of a cooling agent; a warming agent; a relaxing or soothing agent; stimulating or refreshing agent; or mixtures thereof and (c) a propellant at a concentration of about 3% to about 45% by weight of the total composition. The foamable carrier can be an emollient emulsion foamable vehicle, a foamable gel vehicle and can also be a substantially non aqueous foamable vehicle.