N¹-(2-Naphthalen-2-yl-quinolin-4-yl)-ethane-1,2-diamine | 841260-29-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: N¹-(2-Naphthalen-2-yl-quinolin-4-yl)-ethane-1,2-diamine
• 英文别名: N~1~-[2-(Naphthalen-2-yl)quinolin-4-yl]ethane-1,2-diamine；N'-(2-naphthalen-2-ylquinolin-4-yl)ethane-1,2-diamine
• CAS: 841260-29-5
• 化学式: C₂₁H₁₉N₃
• 分子量: 313.402
• InChiKey: KWFZWXJENVNFHB-UHFFFAOYSA-N

物化性质

• 沸点：
  557.7±50.0 °C(Predicted)
• 密度：
  1.225±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  24
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  50.9
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  6-溴-2-甲基-1H-苯并[de]异喹啉-1,3(2H)-二酮 、 N¹-(2-Naphthalen-2-yl-quinolin-4-yl)-ethane-1,2-diamine 在 吡啶 作用下， 反应 10.0h， 以70%的产率得到
  参考文献：
  名称：

  A novel fluorescent sensor for triplex DNA

  摘要：

  A triplex DNA fluorescent sensor based on PET is described. The sensor takes 4-aminonaphthalimide as a reporting group and a triplex-select intercalator as a recognizing group. The results show that it is a selective sensor for T-AT triplex DNA in compared with duplex and ssDNA by fluorescence enhancement in PIPES 20 buffer. (C) 2004 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2004.11.002
• 作为产物：
  描述：

  乙二胺 、 4-chloro-2-(2-naphthyl)quinoline 在 四氯化锡 作用下， 反应 4.0h， 以85%的产率得到N¹-(2-Naphthalen-2-yl-quinolin-4-yl)-ethane-1,2-diamine
  参考文献：
  名称：

  A novel fluorescent sensor for triplex DNA

  摘要：

  A triplex DNA fluorescent sensor based on PET is described. The sensor takes 4-aminonaphthalimide as a reporting group and a triplex-select intercalator as a recognizing group. The results show that it is a selective sensor for T-AT triplex DNA in compared with duplex and ssDNA by fluorescence enhancement in PIPES 20 buffer. (C) 2004 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2004.11.002

文献信息

• A novel fluorescent sensor for triplex DNA
  作者：Erhu Lu、Xiaojun Peng、Fengling Song、Jiangli Fan

  DOI：10.1016/j.bmcl.2004.11.002

  日期：2005.1

  A triplex DNA fluorescent sensor based on PET is described. The sensor takes 4-aminonaphthalimide as a reporting group and a triplex-select intercalator as a recognizing group. The results show that it is a selective sensor for T-AT triplex DNA in compared with duplex and ssDNA by fluorescence enhancement in PIPES 20 buffer. (C) 2004 Elsevier Ltd. All rights reserved.