Cyclohexanol, 2-(2-methoxy-1-methylethyl)-5-methyl- | 180478-68-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: Cyclohexanol, 2-(2-methoxy-1-methylethyl)-5-methyl-
• 英文别名: 2-(1-methoxypropan-2-yl)-5-methylcyclohexan-1-ol
• CAS: 180478-68-6
• 化学式: C₁₁H₂₂O₂
• 分子量: 186.29
• InChiKey: RMNCXEZCLGGIIN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  13
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• EXTERNAL DERMAL COMPOSITION FOR ANTI-AGEING AND METHOD FOR PRODUCING THE SAME
  申请人：HAYASHIBARA CO., LTD.

  公开号：US20150342854A1

  公开（公告）日：2015-12-03

  The present invention has an object to provide an external dermal composition for anti-ageing, which prevents or improves apparent skin problems such as wrinkles, fine wrinkles, blemishes, and saggings caused by increasing age or ageing; and maintains or improves the barrier function and the hyaluronic acid production in the skin. The object is solved by providing an external dermal composition for anti-ageing, which contains an aqueous medium as a base material and one or more ingredients selected from L-ascorbic acid, derivatives thereof, and their salts as an effective ingredient(s).

  本发明的目的是提供一种用于抗衰老的外用皮肤组成物，该组成物可以预防或改善因年龄增长或衰老引起的皮肤问题，如皱纹、细纹、斑点和下垂，并维持或改善皮肤的屏障功能和透明质酸的产生。本发明通过提供一种外用皮肤组成物来实现该目的，该组成物包含水性介质作为基材料，并含有一种或多种从L-抗坏血酸、其衍生物和它们的盐中选择的成分作为有效成分。
• CYCLOHEXANOL DERIVATIVE, AGENT AND COMPOSITION CONTAINING THE SAME FOR IMPARTING PLEASANTLY COOL FEELING, PROCESS FOR PRODUCING THE DERIVATIVE, AND INTERMEDIATE THEREFOR
  申请人：HISAMITSU PHARMACEUTICAL CO. INC.

  公开号：EP0667330A1

  公开（公告）日：1995-08-16

  A cyclohexanol derivative represented by general formula (1), preferably by general formula (1 a) (wherein R represents C1 -C5 linear or branched alkyl). It can impart a sufficient, pleasantly cool feeling to not only the oral mucous membrane but also the skin and is odorless. Further it can provide nearly odorless agent and various compositions for imparting a pleasantly cool feeling.

  由通式（1），最好是通式（1 a）（其中 R 代表 C1 -C5 直链或支链烷基）代表的环己醇衍生物。它不仅能给口腔粘膜，也能给皮肤带来充分、舒适的凉爽感，而且无味。此外，它还能提供近乎无味的制剂和各种组合物，以带来舒适的清凉感。
• LOXOPROFEN-CONTAINING PREPARATION FOR EXTERNAL USE
  申请人：LEAD CHEMICAL COMPANY LTD.

  公开号：EP0947584A1

  公开（公告）日：1999-10-06

  Problem: to provide a favorable antiphlogistic/analgesic containing loxoprofen or a medically acceptable salt thereof. Means for resolution: an antiphlogistic/analgesic for external use containing loxoprofen or a medically acceptable salt thereof and crotamiton.

  问题：提供一种含有洛索洛芬或其医学上可接受的盐的良好的镇痛药。解决方法：一种外用镇痛药，含有洛索洛芬或其医学上可接受的盐和克罗米通。
• SKIN PREPARATION FOR EXTERNAL USE CHARACTERIZED BY CONTAINING SUGAR DERIVATIVE OF a,a-TREHALOSE
  申请人：KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO

  公开号：EP1600143A1

  公开（公告）日：2005-11-30

  The present invention has an object to provide an external dermatological formulation having satisfactory blood flow-promoting effect, antiinflammatory effect, antibacterial effect, moisturizing effect, whitening effect, UV-absorbing effect, UV-scattering effect, antioxidant effect, hair growing effect, hair nourishing effect, emusifying effect, astringent effect, wrinkle-reducing effect, cell-activating effect and/or transdermal absorption-promoting effect with a satisfactory safety and skin feeling; The object is solved by providing an external dermatological formulation comprising a saccharide derivative of α,α-trehalose and one or more members selected from substances having any one of blood flow-promoting effect , antiinflammatory effect, antibacterial effect, moisturizing effect, whitening effect, UV-absorbing effect, UV-scattering effect, antioxidant effect, hair growing efect, hair nourishing effect, emulsifying effect, astringent effect, wrinkle-reducing effect, cell-activating effect and transdermal absorption-promoting effect.

  本发明的目的是提供一种具有令人满意的促进血液流动效果、抗炎效果、抗菌效果、保湿效果、美白效果、紫外线吸收效果、紫外线散射效果、抗氧化效果、生发效果、养发效果、润肤效果、收敛效果、减少皱纹效果、细胞激活效果和/或透皮吸收促进效果，并具有令人满意的安全性和肤感的皮肤外用制剂；本发明的目的是通过提供一种外用皮肤病配方来实现的，该配方包含 α,α-三卤糖的糖衍生物和一种或多种选自具有促进血流效果、抗炎效果、抗菌效果、保湿效果、美白效果、抗菌效果、保湿效果、美白效果中任一种效果的物质、保湿效果、美白效果、紫外线吸收效果、紫外线散射效果、抗氧化效果、生发效果、养发效果、乳化效果、收敛效果、除皱效果、细胞活化效果和透皮吸收促进效果中的任一种。
• FUNCTIONAL POWDERS
  申请人：KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO

  公开号：EP1731134A1

  公开（公告）日：2006-12-13

  The present invention has objects to provide a functional powdery product prepared by allowing carriers to support one or more members selected from vitamin glycosides, and to provide external dermatological agents having satisfactory usability, which contain the above functional powdery products and effectively exert the functions of vitamins. These objects are solved by providing a functional powdery product prepared by allowing carriers such as saccharides to support one or more members selected from vitamin glycosides, and by providing external dermatological agents incorporated with the functional powdery products.

  本发明的目的是提供一种通过允许载体支持一种或多种选自维生素苷的成员而制备的功能性粉状产品，以及提供具有令人满意的可用性的外用皮肤剂，该外用皮肤剂含有上述功能性粉状产品，并能有效发挥维生素的功能。通过提供一种通过允许糖类等载体支持一种或多种选自维生素苷的成分而制备的功能性粉状产品，以及提供与功能性粉状产品结合的外用皮肤剂，上述目的得以解决。