4-(1,2-Dithiolan-3-yl)butan-2-one | 67675-34-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二硫杂环戊烷
• 英文名称: 4-(1,2-Dithiolan-3-yl)butan-2-one
• 英文别名: 4-(dithiolan-3-yl)butan-2-one
• CAS: 67675-34-7
• 化学式: C₇H₁₂OS₂
• 分子量: 176.3
• InChiKey: ZPYXADOPVWLUSV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  10
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  67.7
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• SELECTIVE INHIBITORS OF CLINICALLY IMPORTANT MUTANTS OF THE EGFR TYROSINE KINASE
  申请人：CS Pharmatech Limited

  公开号：EP3399968B1

  公开（公告）日：2021-10-20
• LIPOIC ACID AND DERIVATIVES THEREOF FOR THE TREATMENT OF CYSTINURIA
  申请人：Buck Institute for Research on Aging

  公开号：US20170112804A1

  公开（公告）日：2017-04-27

  In various embodiments methods and composition are provided for the treatment and/or prophylaxis of cystinuria. In certain embodiments the methods involve administering to a mammal in need thereof (e.g., identified as at risk for, or having cystinuria) an effective amount of lipoic acid and/or one or more lipoic acid derivatives.