1,2-Dimyristoyl-sn-glycero-3-phosphate, sodium salt | 80724-31-8

• 物质功能分类: 有机原料 - 羧酸类化合物及衍生物
• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 甘油磷脂
• 英文名称: 1,2-Dimyristoyl-sn-glycero-3-phosphate, sodium salt
• 英文别名: sodium;[(2R)-2,3-di(tetradecanoyloxy)propyl] hydrogen phosphate
• CAS: 80724-31-8
• 化学式: C31H60NaO8P
• 分子量: 614.8
• InChiKey: UBSPGYHFNIKQIP-XXIQNXCHSA-M

物化性质

• 熔点：
  161-166 °C
• 溶解度：
  氯仿：1.6mg/mL

计算性质

• 辛醇/水分配系数(LogP)：
  5.32
• 重原子数：
  41
• 可旋转键数：
  32
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.94
• 拓扑面积：
  122
• 氢给体数：
  1
• 氢受体数：
  8

安全信息

• WGK Germany：
  3

文献信息

• Functional associative coatings for nanoparticles
  申请人：Hainfeld James F.

  公开号：US20080089836A1

  公开（公告）日：2008-04-17

  Described herein are nanoparticles that are coated with a bilayer of molecules formed from surface binding molecules and amphiphatic molecules. The bilayer coating self assembles on the nanoparticles from readily available materials/molecules. The modular design of the bilayer coated nanoparticles provides a means for readily and efficiently optimizing the properties of the bilayer coated nanoparticle compositions. Also described herein are uses of such nanoparticles in medicine, laboratory techniques, industrial and commerical applications.

  本文描述了一种纳米颗粒，其表面涂覆有由表面结合分子和两亲分子形成的双层分子层。该双层涂层可以自组装在纳米颗粒上，使用易得的材料/分子。双层涂层纳米颗粒的模块化设计提供了一种方便和高效地优化其性质的方法。此外，本文还描述了这种纳米颗粒在医学、实验室技术、工业和商业应用中的用途。
• ANNEXIN-COATED PARTICLES
  申请人：Deutsches Krebsforschungszentrum, Stiftung des öffentlichen Rechts

  公开号：EP3692984A1

  公开（公告）日：2020-08-12

  The present invention relates to an annexin-coated particle, comprising a negatively charged phospholipid and an annexin non-covalently coupled thereto. The present invention further relates to a composition comprising an annexin-coated particle. Furthermore, the present invention relates to a product for use in a method of preventing or treating a disease selected from a chronic inflammatory disease, an autoimmune disease, an allergy, and a cancer, said product comprising an annexin-coated particle, and/or a composition. The present invention further relates to a method of preparing an annexin-coated particle.

  本发明涉及一种附件素包被颗粒，包括带负电荷的磷脂和与之非共价偶联的附件素。本发明还涉及一种包含附件素包被颗粒的组合物。此外，本发明还涉及一种用于预防或治疗选自慢性炎症性疾病、自身免疫性疾病、过敏症和癌症的疾病的方法的产品，所述产品包括附件蛋白包被颗粒和/或组合物。本发明还涉及一种制备附件蛋白包被颗粒的方法。
• Annexin-coated particles
  申请人：Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts

  公开号：US20220152149A1

  公开（公告）日：2022-05-19

  The present invention relates to an annexin-coated particle, comprising a negatively charged phospholipid and an annexin non-covalently coupled thereto. The present invention further relates to a composition comprising an annexin-coated particle. Furthermore, the present invention relates to a product for use in a method of preventing or treating a disease selected from a chronic inflammatory disease, an autoimmune disease, an allergy, and a cancer, said product comprising an annexin-coated particle, and/or a composition. The present invention further relates to a method of preparing an annexin-coated particle.
• US7906147B2
  申请人：——

  公开号：US7906147B2

  公开（公告）日：2011-03-15
• [EN] ANNEXIN-COATED PARTICLES<br/>[FR] PARTICULES ENROBÉES D'ANNEXINE
  申请人：DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES ÖFFENTLICHEN RECHTS

  公开号：WO2020161247A1

  公开（公告）日：2020-08-13

  The present invention relates to an annexin-coated particle, comprising a negatively charged phospholipid and an annexin non-covalently coupled thereto. The present invention further relates to a composition comprising an annexin-coated particle. Furthermore, the present invention relates to a product for use in a method of preventing or treating a disease selected from a chronic inflammatory disease, an autoimmune disease, an allergy, and a cancer, said product comprising an annexin-coated particle, and/or a composition. The present invention further relates to a method of preparing an annexin-coated particle.