毒理性
乳香提取物在治疗期间并未与血清酶水平升高有关联，尽管已有一些前瞻性的人类研究详细报告了其对实验室检测结果的影响。在小规模试验中，乳香提取物似乎被很好地耐受，只有轻微的、少数的不良反应，且这些反应在接受安慰剂的人群中出现的频率相似。尽管乳香提取物被广泛用作草本补充剂，但它并未被确凿地与公开发表的临床上明显的肝损伤案例联系起来。乳香常被包含在多成分的膳食补充剂中，其中一些被怀疑与肝损伤有关，但无法确定乳香对损伤的具体贡献。对乳香过敏反应的发生频率也是未知的。
可能性评分：E（不太可能是临床上明显肝损伤的原因）。
其他名称：印度乳香、印度油胶、萨尔ai guggul和萨尔拉基。
药物类别：草本和膳食补充剂。
Boswellia serrata extract has not been linked to serum enzyme elevations during therapy, although there have been few prospective studies in humans that have reported on its effects on laboratory test results in any detail. In small trials, Boswellia extracts have appeared to be well tolerated with only minor and few adverse effects which have been similar in frequency among persons receiving placebo. Despite wide scale use as an herbal supplement, Boswellia extract has not been convincingly linked to published instances of clinically apparent liver injury. Boswellia is often included in multi-ingredient dietary supplements some of which have been implicated in liver injury, but a specific contribution from Boswellia to the injury could not be established. The frequency of hypersensitivity reactions to Boswellia is also not known.
Likelihood score: E (unlikely cause of clinically apparent liver injury).
Other Names: Indian frankincense, Indian oli-banum, Salai guggul and Sallaki.
Drug Class: Herbal and Dietary Supplements
来源:LiverTox
