4-Aminophenol sulfate(2:1) | 63084-98-0

• 物质功能分类: 有机原料 - 羧酸类化合物及衍生物
• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-Aminophenol sulfate(2:1)
• 英文别名: 4-aminophenol;sulfuric acid
• CAS: 63084-98-0
• 化学式: C12H16N2O6S
• 分子量: 316.33
• InChiKey: NSVXDQGLBWXGQK-UHFFFAOYSA-N

物化性质

• LogP：
  -0.287 (est)
• 稳定性/保质期：
  远离氧化物、光和热。

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  21
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  176
• 氢给体数：
  6
• 氢受体数：
  8

安全信息

• 安全说明：
  S26,S36/37/39
• 危险品运输编号：
  2811

制备方法与用途

用途：用于有机合成。

文献信息

• Composition for hair frizz reduction
  申请人：The Procter & Gamble Company

  公开号：US10111820B2

  公开（公告）日：2018-10-30

  A composition directed to a rinse-off composition for hair frizz reduction comprising from about 0.2% to about 20.0% of a moisture control material or mixture of moisture control materials wherein the moisture control material is selected from one or more of the following: a) wherein R is hydrogen or metal ion, R6 is methyl, ethyl, propyl, alkenyl or phenyl having less than 12 carbon atoms and wherein R7, R8, R9, R10, R11, R12 are hydrogen, methyl, ethyl, propyl, phenyl, hydroxyl, methoxy or ethoxy groups; b) an alcohol wherein R13 is an alkyl, alkenyl, straight or branched carbon chains and; and wherein R14 is hydrogen, hydroxyl, alkyl, methyl, ethyl and propyl wherein the structure of such alcohol contains less than 20 total carbon atoms; c) alcohol comprising an unsaturated double bond in the C2 position. d) an alkyl-substituted glycol wherein the structure of such alkyl substituted glycol contains less than 20 carbon atoms; e) a monoalkyl or dialkyl substituted glycerin or mono- or di-esters of glycerin with fatty acids wherein the structure of such monoalkyl- or dialkyl-substituted glycerin or glycerin esters contains less than 20 total carbon atoms; f) wherein R15 could be hydrogen, alkyl, alkenyl, phenyl group and wherein the structure of the R13 group contain less than 20 carbon atoms; g) a fatty acid ester containing from 15-40 total carbon atoms and wherein the moisture control material is weakly to non-acidic and further wherein the moisture control material has protein binding higher than 10 and molecular volume lower than 1500 and log P higher than 0.5 and pKa of 5 or higher and hydrogen-binding higher than 4 and at least about a 4% frizz reduction vs. control composition without the moisture control materials.

  一种用于减少头发毛躁的冲洗组合物，包含约 0.2%至约 20.0%的水分控制材料或水分控制材料混合物，其中水分控制材料选自以下一种或多种： a) 其中 R 是氢或金属离子，R6 是甲基、乙基、丙基、烯基或具有少于 12 个碳原子的苯基，R7、R8、R9、R10、R11、R12 是氢、甲基、乙基、丙基、苯基、羟基、甲氧基或乙氧基； b) 一种醇，其中 R13 是烷基、烯基、直链或支链碳链；以及 R14 是氢、羟基、烷基、甲基、乙基和丙基，其中这种醇的结构包含的碳原子总数少于 20 个； c) 在 C2 位含有不饱和双键的醇。 d) 烷基取代的乙二醇，其中烷基取代的乙二醇结构中含有少于 20 个碳原子； e) 单烷基或二烷基取代的甘油或甘油与脂肪酸的单酯或二酯，其中单烷基或二烷基取代的甘油或甘油酯的结构包含少于 20 个碳原子； f) 其中 R15 可以是氢、烷基、烯基、苯基，而 R13 基团的结构包含少于 20 个碳原子； g) 总碳原子数为 15-40 的脂肪酸酯 其中，水分控制材料是弱酸性至非酸性的，此外，水分控制材料的蛋白质结合力高于 10，分子体积低于 1500，log P 高于 0.5，pKa 为 5 或更高，氢结合力高于 4，与不含水分控制材料的对照组合物相比，至少可减少约 4% 的卷发。
• Method for hair frizz reduction
  申请人：The Procter & Gamble Company

  公开号：US10632054B2

  公开（公告）日：2020-04-28

  A method directed to a hair soaking treatment for frizz reduction comprising immersion of consumer hair into an aqueous composition is disclosed. The corresponding composition comprises from about 0.25% to 20% of a moisture control material or mixture of moisture control materials wherein the moisture control material has structure selected from the group A) wherein R is hydrogen or metal ion, R6 is methyl, ethyl, propyl, alkenyl or phenyl having less than 12 carbon atoms and wherein R7, R8, R9, R10, R11, R12 are hydrogen, methyl, ethyl, propyl, phenyl, hydroxyl, methoxy or ethoxy groups; B) an alcohol wherein R13 is an alkyl, alkenyl, straight or branched carbon chains and; and wherein R14 is hydrogen, hydroxyl, alkyl, methyl, ethyl and propyl wherein the structure of such alcohol contains less than 20 total carbon atoms; C) alcohol comprising an unsaturated double bond in the C2 position. D) an alkyl-substituted glycol wherein the structure of such alkyl substituted glycol contains less than 20 carbon atoms; E) a monoalkyl or dialkyl substituted glycerin or mono- or di-esters of glycerin with fatty acids wherein the structure of such monoalkyl- or dialkyl-substituted glycerin or glycerin esters contains less than 20 total carbon atoms; F) wherein R15 could be hydrogen, alkyl, alkenyl, phenyl group and wherein the structure of the R13 group contain less than 20 carbon atoms; G) a fatty acid ester containing from 15-40 total carbon atoms and wherein the moisture control material of Class II is weakly to non-acidic and further wherein the moisture control material of Class II has protein binding higher than 10 and molecular volume lower than 1500 and log P higher than 0.5 and pKa of 5 or higher and hydrogen-binding higher than 4.

  本发明公开了一种用于减少毛躁的头发浸泡处理方法，包括将消费者的头发浸入水性组合物中。相应的组合物包含约 0.25% 至 20% 的湿度控制材料或湿度控制材料混合物，其中湿度控制材料的结构选自以下组别 A) 其中 R 是氢或金属离子，R6 是甲基、乙基、丙基、烯基或具有少于 12 个碳原子的苯基，R7、R8、R9、R10、R11、R12 是氢、甲基、乙基、丙基、苯基、羟基、甲氧基或乙氧基； B) 一种醇，其中 R13 是烷基、烯基、直链或支链碳链；以及 R14 是氢、羟基、烷基、甲基、乙基和丙基，其中这种醇的结构包含的碳原子总数少于 20 个； C) 在 C2 位含有不饱和双键的醇。 D) 烷基取代的乙二醇，其中烷基取代的乙二醇的结构包含少于 20 个碳原子； E) 单烷基或二烷基取代的甘油或甘油与脂肪酸的单酯或二酯，其中这种单烷基或二烷基取代的甘油或甘油酯的结构包含少于 20 个碳原子； F) 其中 R15 可以是氢、烷基、烯基、苯基，而 R13 基团的结构包含少于 20 个碳原子； G) 总碳原子数为 15-40 的脂肪酸酯 其中 II 类防潮材料为弱酸性至非酸性，此外，II 类防潮材料的蛋白质结合力高于 10，分子体积低于 1500，log P 高于 0.5，pKa 为 5 或更高，氢结合力高于 4。
• Non-aqueous composition for hair frizz reduction
  申请人：The Procter & Gamble Company

  公开号：US10980723B2

  公开（公告）日：2021-04-20

  A non-aqueous hair leave-on composition directed to an aqueous hair leave-on composition for hair frizz reduction comprising from about 0.15% to about 12.0% of a moisture control material or mixture of moisture control materials wherein the moisture control material is selected from one or more of the Class II groups a, b, c, d, e, f and g and wherein the moisture control material of Class II is weakly to non-acidic and further wherein the moisture control material of Class II has protein binding higher than 10 and molecular volume lower than 1500 and log P higher than 0.5 and pKa of 5 or higher and hydrogen-binding higher than 4; and wherein, the non-aqueous carrier is selected from a group consisting of a) hydrocarbons b) silicone fluid c) non-hydrocarbons volatile organic solvents or mixtures thereof.

  一种非水性护发组合物，用于减少头发毛躁的水性护发组合物，包含约 0.15% 至约 12.0%的湿度控制材料或湿度控制材料混合物，其中湿度控制材料选自第II类a、b、c、d、e、f和g组中的一种或多种，第II类湿度控制材料为弱酸性至非酸性，进一步地，第II类湿度控制材料的蛋白质结合力高于10，分子体积低于1500，log P高于0.5，pKa为5或更高，氢结合力高于4；以及其中，非水性载体选自由以下组成的一组 a) 碳氢化合物 b) 硅油 c) 非碳氢化合物挥发性有机溶剂或其混合物。
• COMPOSITION FOR HAIR FRIZZ REDUCTION
  申请人：The Procter & Gamble Company

  公开号：US20160015608A1

  公开（公告）日：2016-01-21

  An aqueous hair leave-on composition directed to an aqueous hair leave-on composition for hair frizz reduction comprising from about 0.15% to about 12.0% of a moisture control material or mixture of moisture control materials wherein the moisture control material is selected from one or more of the following class: 1) Class II having the structure selected from: wherein R is hydrogen or metal ion, R 6 is methyl, ethyl, propyl, alkenyl or phenyl having less than 12 carbon atoms and wherein R 7 , R 8 , R 9 , R 10 , R 11 , R 12 are hydrogen, methyl, ethyl, propyl, phenyl, hydroxyl, methoxy or ethoxy groups; an alcohol wherein R13 is an alkyl, alkenyl, straight or branched carbon chains and; and wherein R14 is hydrogen, hydroxyl, alkyl, methyl, ethyl and propyl wherein the structure of such alcohol contains less than 20 total carbon atoms; c) alcohol comprising an unsaturated double bond in the C2 position. d) an alkyl-substituted glycol wherein the structure of such alkyl substituted glycol contains less than 20 carbon atoms; e) a monoalkyl or dialkyl substituted glycerin or mono- or di-esters of glycerin with fatty acids wherein the structure of such monoalkyl- or dialkyl-substituted glycerin or glycerin esters contains less than 20 total carbon atoms; wherein R 15 could be hydrogen, alkyl, alkenyl, phenyl group and wherein the structure of the R 13 group contain less than 20 carbon atoms; g) a fatty acid ester containing from 15-40 total carbon atoms and wherein the moisture control material of Class II is weakly to non-acidic and further wherein the moisture control material of Class II has protein binding higher than 10 and molecular volume lower than 1500 and log P higher than 0.5 and pKa of 5 or higher and hydrogen-binding higher than 4.
• Method for Hair Frizz Reduction
  申请人：The Procter & Gamble Company

  公开号：US20160287495A1

  公开（公告）日：2016-10-06

  A method directed to a hair soaking treatment for frizz reduction comprising immersion of consumer hair into an aqueous composition is disclosed. The corresponding composition comprises from about 0.25% to 20% of a moisture control material or mixture of moisture control materials wherein the moisture control material has structure selected from the group A) wherein R is hydrogen or metal ion, R 6 is methyl, ethyl, propyl, alkenyl or phenyl having less than 12 carbon atoms and wherein R 7 , R 8 , R 9 , R 10 , R 11 , R 12 are hydrogen, methyl, ethyl, propyl, phenyl, hydroxyl, methoxy or ethoxy groups; B) an alcohol wherein R13 is an alkyl, alkenyl, straight or branched carbon chains and; and wherein R14 is hydrogen, hydroxyl, alkyl, methyl, ethyl and propyl wherein the structure of such alcohol contains less than 20 total carbon atoms; C) alcohol comprising an unsaturated double bond in the C2 position. D) an alkyl-substituted glycol wherein the structure of such alkyl substituted glycol contains less than 20 carbon atoms; E) a monoalkyl or dialkyl substituted glycerin or mono- or di-esters of glycerin with fatty acids wherein the structure of such monoalkyl- or dialkyl-substituted glycerin or glycerin esters contains less than 20 total carbon atoms; F) wherein R 15 could be hydrogen, alkyl, alkenyl, phenyl group and wherein the structure of the R 13 group contain less than 20 carbon atoms; G) a fatty acid ester containing from 15-40 total carbon atoms and wherein the moisture control material of Class II is weakly to non-acidic and further wherein the moisture control material of Class II has protein binding higher than 10 and molecular volume lower than 1500 and log P higher than 0.5 and pKa of 5 or higher and hydrogen-binding higher than 4.