| 1361552-42-2

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• CAS: 1361552-42-2
• 化学式: C₂₅H₂₇F₃O₁₀
• 分子量: 544.479
• InChiKey: HZLWEDYHYMZQSY-QYMKOZBSSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.74
• 重原子数：
  38.0
• 可旋转键数：
  4.0
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.64
• 拓扑面积：
  148.82
• 氢给体数：
  3.0
• 氢受体数：
  10.0

反应信息

• 作为产物：
  描述：

  (2S)-2-hydroxyneomajucin 、 甲氧基-三氟甲基苯 在 4-二甲氨基吡啶 、 三乙胺 作用下， 以 二氯甲烷 为溶剂， 反应 24.0h， 生成
  参考文献：
  名称：

  The first examples of seco-prezizaane-type norsesquiterpenoids with neurotrophic activity from Illicium jiadifengpi

  摘要：

  Two seco-prezizaane-type sesquiterpenoids (2R)-hydroxy-norneomajucin (1) and jiadifenone (2) that represent the first examples of nor-type were isolated from the methanol extract of the pericarps of Illicium jiadifengpi. Their structures and the absolute configuration of 1 were established by the analysis of spectroscopic data and chemical conversion of (25)-hydroxyneomajucin to 1, respectively. In addition, compound 1 exhibited neurotrophic activity to significantly promote neurite outgrowth in the primary cultured rat cortical neurons at concentrations ranging from 1 to 10 mu mol L-1. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2011.12.107