| 1340547-54-7

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 肉桂酸及其衍生物
• CAS: 1340547-54-7
• 化学式: C₁₆H₂₂OS
• 分子量: 262.416
• InChiKey: NZHKGYYBHSIQCU-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  、 苯肼 在 potassium tert-butylate 作用下， 以 叔丁醇 为溶剂， 反应 9.0h， 以92%的产率得到5-(4-tert-butylphenyl)-3-methyl-1-phenyl-1H-pyrazole
  参考文献：
  名称：

  Regioselective synthesis of multisubstituted pyrazoles via cyclocondensation of β-thioalkyl-α,β-unsaturated ketones with hydrazines

  摘要：

  Multisubstituted pyrazoles were efficiently synthesized by cyclocondensation of beta-thioalkyl-alpha,beta-unsaturated ketones with hydrazines under relatively mild conditions. A one-pot synthetic protocol through tandem Liebeskind-Srogl cross-coupling/cyclocondensation using alpha-oxo ketene dithioacetals as the starting materials was also realized for the same purpose. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2011.08.168