| 941303-84-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• CAS: 941303-84-0
• 化学式: C₂₀H₃₁NO₈
• 分子量: 413.468
• InChiKey: BSQUCDYPEAPDKM-HZSPNIEDSA-N

反应信息

• 作为反应物：
  描述：

  在 三氟乙酸 作用下， 以 二氯甲烷 为溶剂， 以100%的产率得到(3S,4R,5S)-4-amino-3,5-dihydroxy-cyclohex-1-en-carboxylic acid
  参考文献：
  名称：

  Parallel synthesis of individual shikimic acid-like molecules using a mixture-operation strategy and ring-closing enyne metathesis

  摘要：

  Three new diastereomeric shikimic acid analogues (4-amino-3,5-dihydroxyl-cyclohex-1-en-carboxylic acids, 16) bearing a C-4 amino group were synthesized in parallel by a mixture-operation protocol. Ring-closing enyne metathesis (RCEYM) under ethylene atmosphere was successfully employed to construct the desired carbocycles in high efficiency. The absolute configurations of each final product were confirmed by the ID and 2D NMR techniques. (C) 2007 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2007.03.118
• 作为产物：
  描述：

  二碳酸二叔丁酯 在 RuCl2(1,3-dimesityl-imidazolidin-2-yl)(PCy3)(=CHPh) 2,6-二甲基吡啶 、 4-二甲氨基吡啶 、 sodium chlorite 、 sodium periodate 、 potassium dihydrogenphosphate 、 四氧化锇 、 2-甲基-2-丁烯 、 乙烯 作用下， 以 1,4-二氧六环 、 二氯甲烷 、 水 、 乙腈 、 叔丁醇 为溶剂， 生成
  参考文献：
  名称：

  Parallel synthesis of individual shikimic acid-like molecules using a mixture-operation strategy and ring-closing enyne metathesis

  摘要：

  Three new diastereomeric shikimic acid analogues (4-amino-3,5-dihydroxyl-cyclohex-1-en-carboxylic acids, 16) bearing a C-4 amino group were synthesized in parallel by a mixture-operation protocol. Ring-closing enyne metathesis (RCEYM) under ethylene atmosphere was successfully employed to construct the desired carbocycles in high efficiency. The absolute configurations of each final product were confirmed by the ID and 2D NMR techniques. (C) 2007 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2007.03.118