(1S,4R,6R,8R)-3-propyl-4-ethyl-11,11-dimethyl-5-oxa-3-aza-tricyclo[6.2.1.0(1,6)]undecan-2-one | 1197870-08-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: (1S,4R,6R,8R)-3-propyl-4-ethyl-11,11-dimethyl-5-oxa-3-aza-tricyclo[6.2.1.0(1,6)]undecan-2-one
• CAS: 1197870-08-8
• 化学式: C₁₆H₂₇NO₂
• 分子量: 265.396
• InChiKey: ZIDZSZOYGOBILI-JXFSHQFZSA-N

反应信息

• 作为产物：
  描述：

  (1S,2R,4R)-2-hydroxy-7,7-dimethyl-N,N-dipropyllbicyclo[2.2.1]heptane-1-carboxamide 在 N,N,N,N-tetraethylammonium tetrafluoroborate 作用下， 以 乙醇 、 乙腈 为溶剂， 以43%的产率得到(1S,4S,6R,8R)-3-propyl-4-ethyl-11,11-dimethyl-5-oxa-3-aza-tricyclo[6.2.1.0(1,6)]undecan-2-one
  参考文献：
  名称：

  Highly diastereoselective synthesis of pyrido[2,1-b][1,3]oxazin-4(6H)-one by intramolecular anodic oxidation

  摘要：

  This paper describes a method for the intramolecular anodic oxidation of omega-hydroxyl amides. Products were obtained in acceptable yields from different starting materials using various applied currents, charge, and reactant concentrations. Compounds 1a and 1d afforded a single diastereomer in 67% yield when the applied current and reactant concentration were 100 mA and 0.04 M. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetasy.2009.08.017