2'-O-succinylcytidine-3',5'-cyclic monophosphate | 104809-17-8

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2'-O-succinylcytidine-3',5'-cyclic monophosphate
• CAS: 104809-17-8
• 化学式: C₁₃H₁₅N₂O₁₁P
• 分子量: 406.243
• InChiKey: FRZOLTRWRQPRJM-GUOLCYNNSA-N

物化性质

• 密度：
  1.76±0.1 g/cm3(Predicted)

反应信息

• 作为反应物：
  描述：

  2'-O-succinylcytidine-3',5'-cyclic monophosphate 在 三辛胺 、 phosphate buffer 、 Dowex 1-X₈ formate 、 chloroamine-T 、 氯甲酸乙酯 、 sodium iodide 作用下， 反应 3.25h， 生成 2'-O-succinyliodotyrosinyl methyl ester cytidine-3',5'-cyclic monophosphate
  参考文献：
  名称：

  Identification of cyclic nucleotide derivatives synthesized for radioimmunoassay development by fast atom bombardment with collision-induced dissociation and mass-analysed ion kinetic energy spectroscopy

  摘要：

  AbstractThe syntheses of 2′‐O‐succinyl, 2′‐O‐succinyltyrosinyl methyl ester and 2′‐O‐succinyliodotyrosinyl methyl ester derivatives of a cyclic nucleotide, derivatives necessary for the successful development of a specific radioimmuno‐assay, are described. Fast atom bombardment with collision‐induced dissociation and mass‐analysed ion kinetic energy spectroscopy were used to verify the positions of substitution and the retention of the 3′,5′‐cyclic phosphate moiety. Comparison of spectra produced after different iodination times permitted the optimization of the reaction conditions.

  DOI：

  10.1002/oms.1210280813
• 作为产物：
  描述：

  丁二酸酐 、 尿苷 3',5'-环单磷酸酯 在 TEA 作用下， 以 水 为溶剂， 反应 1.25h， 生成 2'-O-succinylcytidine-3',5'-cyclic monophosphate
  参考文献：
  名称：

  Identification of cyclic nucleotide derivatives synthesized for radioimmunoassay development by fast atom bombardment with collision-induced dissociation and mass-analysed ion kinetic energy spectroscopy

  摘要：

  AbstractThe syntheses of 2′‐O‐succinyl, 2′‐O‐succinyltyrosinyl methyl ester and 2′‐O‐succinyliodotyrosinyl methyl ester derivatives of a cyclic nucleotide, derivatives necessary for the successful development of a specific radioimmuno‐assay, are described. Fast atom bombardment with collision‐induced dissociation and mass‐analysed ion kinetic energy spectroscopy were used to verify the positions of substitution and the retention of the 3′,5′‐cyclic phosphate moiety. Comparison of spectra produced after different iodination times permitted the optimization of the reaction conditions.

  DOI：

  10.1002/oms.1210280813