| 872168-92-8

• 分子结构分类: 有机化合物 - 有机氧化合物
• CAS: 872168-92-8
• 化学式: C₂₄H₁₆N₂O₂
• 分子量: 364.403
• InChiKey: SWZOYMVMGYDFHZ-QPLCGJKRSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.28
• 重原子数：
  28.0
• 可旋转键数：
  0.0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  43.18
• 氢给体数：
  0.0
• 氢受体数：
  4.0

反应信息

• 作为反应物：
  描述：

  以 氘代氯仿 为溶剂， 生成
  参考文献：
  名称：

  Photoisomerization as a trigger for Bergman cyclization: Synthesis and reactivity of azoenediynes

  摘要：

  Cyclic enediynes 1a and 2a containing stable E-azo moiety (azoenediynes) have been synthesized. These compounds upon irradiation with long wavelength UV isomerize to the Z-compounds 1b and 2b, which can be thermally reisomerized to the Z compounds. Reactivity studies toward BC using DSC predictably indicate higher reactivity for the Z-isomers. Our studies may provide a novel way to modulate the reactivity of enediynes under thermal or photochemical conditions. (c) 2005 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2005.09.005
• 作为产物：
  描述：

  1,2-bis(1-methylsulfonyloxyprop-1-yn-1-yl)benzene 在 caesium carbonate 、 lithium bromide 作用下， 以 四氢呋喃 、 甲醇 、 N,N-二甲基甲酰胺 为溶剂， 反应 7.0h， 生成
  参考文献：
  名称：

  Photoisomerization as a trigger for Bergman cyclization: Synthesis and reactivity of azoenediynes

  摘要：

  Cyclic enediynes 1a and 2a containing stable E-azo moiety (azoenediynes) have been synthesized. These compounds upon irradiation with long wavelength UV isomerize to the Z-compounds 1b and 2b, which can be thermally reisomerized to the Z compounds. Reactivity studies toward BC using DSC predictably indicate higher reactivity for the Z-isomers. Our studies may provide a novel way to modulate the reactivity of enediynes under thermal or photochemical conditions. (c) 2005 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2005.09.005