4α,18-epoxytafricanin A | 82225-37-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: 4α,18-epoxytafricanin A
• 英文别名: tafricanin A epoxide
• CAS: 82225-37-4
• 化学式: C₂₂H₂₄O₈
• 分子量: 416.428
• InChiKey: UALFLPWLEQXRGU-LCJNUFCQSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.3
• 重原子数：
  30
• 可旋转键数：
  4
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.64
• 拓扑面积：
  112
• 氢给体数：
  0
• 氢受体数：
  8

反应信息

• 作为产物：
  描述：

  teugracilin B 在 12-I-5-triacetoxyperiodinane 作用下， 以 二氯甲烷 为溶剂， 反应 3.5h， 以11 mg的产率得到4α,18-epoxytafricanin A
  参考文献：
  名称：

  Neo-clerodane diterpenoids fromTeucrium polium ssp.Aurasianum

  摘要：

  Five neo-clerodane diterpenes were isolated from the aerial parts of Teucrium polium ssp. aurasianum, One was known (teumicropodine) and the others were new: 3-deacetylteumicropodine, 3,20-bis-deacetylteupyreinidine, 6,20-bis-deacetylteupyreinidine and 3,6,20-tri-deacetylteupyreinidine. Their structures and absolute stereochemistry were elucidated by spectral and correlation techniques.

  DOI：

  10.1016/s0031-9422(00)89588-6

文献信息

• A neo-clerodane glucoside and neo-clerodane diterpenoids from Teucrium flavum subsp. Glaucum
  作者：Giuseppe Savona、Franco Piozzi、Orietta Servettaz、Benjamín Rodríguez、Francisco Fernández-Gadea、Manuel Martín-Lomas

  DOI：10.1016/s0031-9422(00)85039-6

  日期：1984.4

  Abstract From the aerial part of Teucrium flavum subsp. glaucum a new neo-clerodane diterpenoid, teuflavin, and a new 19-nor-neo-clerodane glucoside, teuflavoside, have been isolated, besides the previously known diterpene teuflin. The structures of teuflavin (19-acetoxy-4α,18:15,16-diepoxy-6β-hydroxy-3-keto-neo-cleroda-13(16),14-diene-20,ξ,12 S -hemiacetal) and teuflavoside (18-acetoxy-15,16-epox

  摘要来自 Teucrium flavum subsp. 的地上部分。除了先前已知的二萜 teuflin 之外，glaucum 还分离了一种新的新克罗丹二萜类化合物 teuflavin 和一种新的 19-nor-neo-neo-clerodane 葡萄糖苷 teuflavoside。teuflavin (19-acetoxy-4α,18:15,16-diepoxy-6β-hydroxy-3-keto-neo-cleroda-13(16),14-diene-20,ξ,12 S-hemiacetal)的结构和teuflavoside (18-acetoxy-15,16-epoxy-19-nor-neo-cleroda-4,13(16),14-trien-20,12 S-olid-6β-yl-2'-O-acetyl-β - d -吡喃葡萄糖苷）是通过化学和光谱方法并通过与已知化合物的相关性建立的。
• Neo-clerodane diterpenoids from teucrium lepicephalum and teucrium buxifolium
  作者：Giuseppe Savona、Franco Piozzi、Orietta Servettaz、Benjamin Rodriguez、Juan A. Hueso-Rodriguez、Maria C. De La Torre

  DOI：10.1016/s0031-9422(00)84512-4

  日期：1986.1

  Abstract Three new neo-clerodane diterpenoids, teulepicin, 19-acetylteulepicin and teulepicephin, have been isolated, together with the previously known flavone cirsiliol from the aerial parts of Teucrium lepicephalum . The structures of the diterpenoids were established by chemical and spectroscopic means and by correlation with known substances. In addition, 19-acetylteulepicin and the already known

  摘要 三种新的新克罗丹二萜类化合物 teulepicin、19-acetylteulepicin 和 teulepicephin，以及先前已知的黄酮 cirsiliol 从 Teucrium lepicephalum 地上部分被分离出来。二萜类化合物的结构是通过化学和光谱方法以及与已知物质的相关性确定的。此外，已从 T. buxifolium 物种中分离出 19-acetylteulepicin 和已知的新克罗丹二萜类化合物 19-acetylgnaphalin。
• Hanson, James R.; Rivett, Douglas E. A.; Ley, Steven V., Journal of the Chemical Society. Perkin transactions I, <hi>1982</hi>, p. 1005 - 1008
  作者：Hanson, James R.、Rivett, Douglas E. A.、Ley, Steven V.、Williams, David J.

  DOI：——

  日期：——