| 1191385-02-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• CAS: 1191385-02-0
• 化学式: C₁₅₄H₂₅₄O₆₆S₆Si₃
• 分子量: 3438.32
• InChiKey: GUGDVHOPVOLCGJ-IHKFRCBDSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.97
• 重原子数：
  229.0
• 可旋转键数：
  102.0
• 环数：
  17.0
• sp3杂化的碳原子比例：
  0.82
• 拓扑面积：
  1071.18
• 氢给体数：
  42.0
• 氢受体数：
  72.0

反应信息

• 作为产物：
  描述：

  Tris(3-bromopropyl)-[3-[2,3,4,5-tetraphenyl-1-[3-[tris(3-bromopropyl)silyl]propyl]silol-1-yl]propyl]silane 、 ω-acetylthiopentyl 4-O-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)- 在 sodium methylate 、 吡啶 、 乙酸酐 作用下， 以 甲醇 、 N,N-二甲基甲酰胺 为溶剂， 生成
  参考文献：
  名称：

  Fluorescence quenching detection of peanut agglutinin based on photoluminescent silole-core carbosilane dendrimer peripherally functionalized with lactose

  摘要：

  A glycocluster peripherally functionalized with a lactose (Lac: Gal beta 1 -> 4Glc beta 1-) derivative possessing a silole moiety as a luminophore was synthesized. The photoluminescence spectrum of the glycocluster showed extremely strong emission at 474 nm and the absolute quantum yield was estimated to be 92% in distilled water. The emission intensity was decreased by increasing the amount of peanut agglutinin (PNA), a lactose-binding lectin, and plots of the relative fluorescence intensity revealed a decline of 95% in emission intensity. Fluorescence quenching of the glycocluster upon mixing with PNA could be easily observed by the naked eye under UV irradiation, whereas no distinct change in fluorescence properties of the glycocluster was observed when wheat germ agglutinin (WGA) was employed. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2009.07.153