4-(2,4-二氯苯氧基)苯酚 | 40843-73-0

• 物质功能分类: 有机原料 - 醇、酚、酚醇类化合物及衍生物 - 酚及其卤化、磺化、硝化或亚硝化衍生物
• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 4-(2,4-二氯苯氧基)苯酚
• 中文别名: 4-(2,4-氯苯氧基)苯酚
• 英文名称: 4-(2',4'-dichlorophenoxy)-phenol
• 英文别名: 4-(2,4-dichlorophenoxy)-phenol；4-(2,4-Dichlorphenoxy)-phenol；4-(2,4-dichlorophenoxy)phenol；4-(2'.4'-dichlorophenoxy)-phenol；4-(2',4'-dichlorophenoxy)phenol；4-(2,4-Dichloro-phenoxy)-phenol
• CAS: 40843-73-0
• 化学式: C₁₂H₈Cl₂O₂
• 分子量: 255.1
• InChiKey: DPRSKCAGYLXDCY-UHFFFAOYSA-N

物化性质

• 沸点：
  354.0±37.0 °C(Predicted)
• 密度：
  1.398±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  2

安全信息

• 危险品标志：
  Xn,N
• 安全说明：
  S60,S61
• 危险类别码：
  R22
• WGK Germany：
  3
• 海关编码：
  2909500000
• 储存条件：
  室温和干燥环境

反应信息

• 作为反应物：
  描述：

  4-(2,4-二氯苯氧基)苯酚 在 sodium hydroxide 、 potassium carbonate 作用下， 以 乙腈 为溶剂， 反应 23.5h， 生成 diclofop
  参考文献：
  名称：

  Nestler, Hans Juergen; Bieringer, Hermann, Zeitschrift fur Naturforschung, Teil B: Anorganische Chemie, Organische Chemie, 1980, vol. 35, # 3, p. 366 - 371

  摘要：

  DOI：
• 作为产物：
  描述：

  2,4-二氯-4’-氨基二苯醚 生成 4-(2,4-二氯苯氧基)苯酚
  参考文献：
  名称：

  DE2136828

  摘要：

  公开号：

文献信息

• Neue Benzylester von Cyclopropancarbon- und Phenylessigsäuren als potentielle Insektizide / New Benzylic Esters of Cyclopropanecarboxylic and Phenylacetic Acids as Potential Insecticides
  作者：Wolfgang Welter、Thomas Hüttelmaier、Karl Matterstock、Hilmar Mildenberger

  DOI：10.1515/znb-1982-0726

  日期：1982.7.1

  Abstract Pyrethroids are known insecticides with a great potency to a wide range of insect species. Derivatizations at the benzylic position and at the second aromatic ring system of these pyrethroids yielded new benzylic esters with insecticidal activity. Methods for the synthesis of these compounds are reviewed.

  摘要 拟除虫菊酯是已知的杀虫剂，对多种昆虫物种具有很强的效力。在这些拟除虫菊酯的苄基位置和第二个芳环系统上的衍生化产生了具有杀虫活性的新的苄基酯。综述了这些化合物的合成方法。
• Process for producing optically active 2-phenoxypropionic acid
  申请人：Kirin Beer Kabushiki Kaisha

  公开号：US04803301A1

  公开（公告）日：1989-02-07

  There is provided a process for producing an optically active 2-phenoxypropionic acid, which comprises allowing an optically active lactic ester represented by the following formula (I) to react with a phenol represented by the following formula (II) in the copresence of a reagent A and a reagent B defined below to form an optically active 2-phenoxypropionic ester represented by the following formula (III), and liberating an optically active 2-phenoxypropionic acid represented by the following formula (IV) from the optically active 2-phenoxypropionic ester: ##STR1## wherein R.sup.1 represents a group to form a monovalent ester, which can be eliminated from the compound (III) under weakly basic to acidic conditions and R.sup.2 represents a hydrogen atom or 1 to 5 substituents which do not interfere in the reaction between the compounds (I) and (II); a reagent A being at least one compound selected from the group consisting of trialkylphosphine, trialkylphosphite, triarylphosphine and triarylphosphite; and a reagent B being at least one compound selected from the group consisting of dialkylazodicarboxylate and diarylazodicarboxylate.

  提供一种生产光学活性2-苯氧基丙酸的方法，包括允许以下式(I)所代表的光学活性乳酸酯与以下式(II)所代表的苯酚在下述定义的试剂A和试剂B的共存下反应，形成以下式(III)所代表的光学活性2-苯氧基丙酸酯，并从光学活性2-苯氧基丙酸酯中释放出以下式(IV)所代表的光学活性2-苯氧基丙酸：其中R.sup.1代表形成一价酯的基团，可以在弱碱性至酸性条件下从化合物(III)中消除，R.sup.2代表氢原子或在化合物(I)和(II)之间的反应中不干扰的1至5个取代基；试剂A至少是从三烷基膦、三烷基膦酸酯、三芳基膦和三芳基膦酸酯组成的群体中选择的至少一种化合物；试剂B至少是从二烷基偶氮二羧酸酯和二芳基偶氮二羧酸酯组成的群体中选择的至少一种化合物。
• 2-(Substituted phenoxy)propionic acid derivatives and their uses for
  申请人：Hokko Chemical Industry Co., Ltd.

  公开号：US04447259A1

  公开（公告）日：1984-05-08

  New 2-(substituted-phenoxy)propionic acid derivatives are provided, which have the structure of the general formula: ##STR1## and R.sub.2 is a hydrogen atom or a lower alkyl group. They have a high herbicidal activity to weeds, particularly graminaceous weeds, while they have little or no phytotoxicity to broad leaved crop plants and are therefore useful as selective herbicide.

  提供了新的2-(取代苯氧基)丙酸衍生物，其具有一般式的结构：##STR1##和R.sub.2是氢原子或较低的烷基基团。它们对杂草，特别是禾本科杂草具有很高的除草活性，同时对宽叶作物几乎没有植物毒性，因此可作为选择性除草剂。
• Herbicidal esters of D-1-(phenoxy-4-phenoxy)propionic acid
  申请人：Hoechst Aktiengesellschaft

  公开号：US04531969A1

  公开（公告）日：1985-07-30

  Optically active enantiomers of the formula I ##STR1## where R is a group of the formulae ##STR2## R.sub.1 and R.sub.2, among others, are halogen or CF.sub.3 and Z is a carboxyl, carboxylate, carboxylic acid ester, thioester, carbonamide, carboxylic acid anilide, carbohydrazide or thioamide group, are interesting herbicides the effect of which is considerably superior to that of the optically inactive racemates.

  化学式为I的光学活性对映体，其中R是化学式中的一个基团，R.sub.1和R.sub.2等等是卤素或CF.sub.3，Z是一个羧基、羧酸盐、羧酸酯、硫酯、碳酰胺、羧酸苯胺、羧酸酰肼或硫代酰胺基团，是一种有趣的除草剂，其效果比光学不活性的混合物要好得多。
• Evaluation of the Elbs Persulfate Oxidation Reaction for the Preparation of Aryloxyphenoxypropionate Herbicides
  作者：KG Watson、A Serban

  DOI：10.1071/ch9951503

  日期：——

  A new, simple method for the preparation of several 4-( aryloxy )phenols (2a-d) and alkyl 2-(4-hydroxyphenoxy)propionates (3a,b) is described. These compounds are key precursors for the synthesis of important aryloxyphenoxypropionate herbicides (1a-d). The method uses the Elbs persulfate oxidation to convert phenol into 4-hydroxyphenyl sulfate (5). The free hydroxy group is then reacted with various aryl halides and alkyl 2-halopropionates. Mild hydrolysis of the sulfate group with boiling acetic acid then gives the products (2a-d) and (3a,b), generally in modest to good yield.

  本文介绍了制备几种 4-(芳氧基)苯酚（2a-d）和 2-(4-羟基苯氧基)丙酸烷基酯（3a,b）的简单新方法。这些化合物是合成重要的芳氧基苯氧基丙酸酯类除草剂（1a-d）的关键前体。该方法使用 Elbs 过硫酸盐氧化法将苯酚转化为 4-羟基苯基硫酸盐 (5)。然后，游离羟基与各种芳基卤化物和 2-卤丙酸烷基酯反应。然后用沸腾的乙酸对硫酸基团进行温和的水解，得到产物（2a-d）和（3a,b），通常产率不高但也很好。