| 1414864-24-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• CAS: 1414864-24-6
• 化学式: C₄₂H₆₈O₁₈
• 分子量: 860.991
• InChiKey: MNBVCQIKQPRECA-HSZFFXDVSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.11
• 重原子数：
  60.0
• 可旋转键数：
  28.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  221.02
• 氢给体数：
  0.0
• 氢受体数：
  18.0

反应信息

• 作为产物：
  描述：

  溴代十六烷 在 palladium 10% on activated carbon 、 氢气 、 sodium hydride 作用下， 以 吡啶 、 甲醇 、 水 、 N,N-二甲基甲酰胺 、 正丁醇 为溶剂， 反应 217.5h， 生成
  参考文献：
  名称：

  Synthesis of 6-O-Hexadecyl- and 6-O-Octylsucroses and Their Self-Assembling Properties Under Aqueous Conditions

  摘要：

  This paper reports the synthesis and self-assembling properties of 6-O-hexadecyl- and 6-O-octylsucroses. Mono-etherification of 2,3,4,1',3',4'-hexa-O-benzylsucrose with the corresponding alkyl bromides predominantly took place at the glucose 6-position and the products were isolated by silica gel column chromatography. Benzyl groups in the isolated products were cleaved to yield the target derivatives. The SEM, TEM, XRD, and DLS results indicated that 6-O-alkylsucroses formed vesicle-type particles via formation of lamellar-like planes under aqueous conditions, which were further merged by fusion of the planes to construct larger aggregates. The self-assembling properties of the materials were different from those of the previously reported 6-O- and 6'-O-hexadecylsucroses mixture.

  DOI：

  10.1080/07328303.2012.702250