2-trans-cinnamoyl-cyclohexanone | 58369-47-4

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 肉桂酸及其衍生物
• 英文名称: 2-trans-cinnamoyl-cyclohexanone
• 英文别名: 2-trans-Cinnamoyl-cyclohexanon；2-[(2E)-1-Oxo-3-phenyl-2-propen-1-yl]cyclohexanone；2-[(E)-3-phenylprop-2-enoyl]cyclohexan-1-one
• CAS: 58369-47-4
• 化学式: C₁₅H₁₆O₂
• 分子量: 228.291
• InChiKey: SRWJUKPWCFFRGO-ZHACJKMWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  17
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  34.1
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  环己酮 在 sodium amide 作用下， 生成 2-trans-cinnamoyl-cyclohexanone
  参考文献：
  名称：

  Synthesis of Certain β-Diketones from Acid Chlorides and Ketones by Sodium Amide. Mono versus Diacylation of Sodio Ketones with Acid Chlorides¹

  摘要：

  DOI：

  10.1021/ja01604a032

文献信息

• METHODS AND COMPOSITIONS FOR TERPENOID SYNTHESIS
  申请人：University of Florida Research Foundation, Inc.

  公开号：US20190270700A1

  公开（公告）日：2019-09-05

  In one aspect, the disclosure relates to methods for preparation of terpene and terpene-like molecules. In a further aspect, the disclosure relates to the products of the disclosed methods, i.e., terpene and terpene-like molecules prepared using the disclosed methods. Intermediates for the synthesis of a wide variety of terpenoids are γ-allyl Knoevenagel adducts or quasi γ-allyl Knoevenagel adducts are disclosed. In various aspects, methods of preparing terpenoids through these intermediates are disclosed. The methods can comprise a-alkylation of an allylic electrophile followed by ring-closure metathesis to a polycyclic terpenoid structure. In a further aspect, the disclosure pertains to terpenoid frameworks, and compounds prepared via disclosed oxidation and substitution reactions on the disclosed terpenoid frameworks. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.
• Synthesis of Certain β-Diketones from Acid Chlorides and Ketones by Sodium Amide. Mono versus Diacylation of Sodio Ketones with Acid Chlorides¹
  作者：Bruce O. Linn、Charles R. Hauser

  DOI：10.1021/ja01604a032

  日期：1956.12