N-(benzyloxy)-5-((2-(tert-butyl)-5-methyloxazol-4-yl)methyl)-2-methyl-1,3-dioxane-2-carboxamide | 1297530-75-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: N-(benzyloxy)-5-((2-(tert-butyl)-5-methyloxazol-4-yl)methyl)-2-methyl-1,3-dioxane-2-carboxamide
• 英文别名: 5-[(2-tert-butyl-5-methyl-1,3-oxazol-4-yl)methyl]-2-methyl-N-phenylmethoxy-1,3-dioxane-2-carboxamide
• CAS: 1297530-75-6
• 化学式: C₂₂H₃₀N₂O₅
• 分子量: 402.491
• InChiKey: VAOBQCRASFPHMI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  29
• 可旋转键数：
  7
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.55
• 拓扑面积：
  82.8
• 氢给体数：
  1
• 氢受体数：
  6

文献信息

• [EN] COMPOUNDS FOR THE TREATMENT OF DYSLIPIDEMIA AND RELATED DISEASES<br/>[FR] COMPOSÉS POUR LE TRAITEMENT DE LA DYSLIPIDÉMIE ET DE MALADIES ASSOCIÉES
  申请人：CADILA HEALTHCARE LTD

  公开号：WO2011051961A1

  公开（公告）日：2011-05-05

  The present invention relates to compounds of the general formula (I), their tautomeric forms, their stereoisomers, their pharmaceutically acceptable salts, pharmaceutical compositions containing them, methods for their preparation, use of these compounds in medicine and the intermediates involved in their preparation '

  本发明涉及一般式（I）的化合物，它们的互变异构体、立体异构体、药用可接受盐、含有它们的药物组合物、其制备方法、这些化合物在医学中的应用以及其制备中涉及的中间体。
• COMPOUNDS FOR THE TREATMENT OF DYSLIPIDEMIA AND RELATED DISEASES
  申请人：Pingali Harikishore

  公开号：US20120252796A1

  公开（公告）日：2012-10-04

  The present invention relates to compounds of the general formula (I), their tautomeric forms, their stereoisomers, their pharmaceutically acceptable salts, pharmaceutical compositions containing them, methods for their preparation, use of these compounds in medicine and the intermediates involved in their preparation.

  本发明涉及一般式（I）化合物、它们的互变异构体、立体异构体、药学上可接受的盐、含有它们的药物组合物、其制备方法、这些化合物在医学中的应用以及其制备过程中涉及的中间体。
• Compounds for the treatment of dyslipidemia and related diseases
  申请人：CADILA HEALTHCARE LIMITED

  公开号：EP2567957A1

  公开（公告）日：2013-03-13

  The present invention relates to compounds of the general formula (I), their tautomeric forms, their stereoisomers, their pharmaceutically acceptable salts, pharmaceutical compositions containing them, methods for their preparation, use of these compounds in medicine and the intermediates involved in their preparation.

  本发明涉及通式（I）的化合物、它们的同分异构体、它们的立体异构体、它们的药学上可接受的盐、含有它们的药物组合物、它们的制备方法、这些化合物在医学中的用途以及制备它们所涉及的中间体。