2-mercaptoquinoline-3-carbaldehyde hydrazone | 1179529-77-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 2-mercaptoquinoline-3-carbaldehyde hydrazone
• CAS: 1179529-77-1
• 化学式: C₁₀H₉N₃S
• 分子量: 203.268
• InChiKey: XHHBAXZZTJTRLJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.82
• 重原子数：
  14.0
• 可旋转键数：
  1.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  51.27
• 氢给体数：
  2.0
• 氢受体数：
  4.0

反应信息

• 作为反应物：
  描述：

  苯草灭 、 2-mercaptoquinoline-3-carbaldehyde hydrazone 在 吡啶 作用下， 以 乙醇 为溶剂， 以68%的产率得到3-{[(2-mercaptoquinolin-3-yl)methylene]amino}-2-phenylquinazolin-4(3H)-one
  参考文献：
  名称：

  Synthesis of Quinoline-Based Thieno-Seleno-Phenylquinazolinones

  摘要：

  The synthesis of quinoline-substituted phenylquinazolinones containing sulfur and selenium is described. These molecules were isolated from a series of reactions of 2-phenyl-4H-3,1-benzoxazin-4-one with 2-chloro, 2-thieno, and 2-selenoquinoline-3-carbaldehyde hydrazones. The structure of the isolated compounds has been elucidated on the basis of IR, 1H NMR, mass spectral, and elemental analysis data.

  DOI：

  10.1080/10426500802176945
• 作为产物：
  描述：

  3-formyl-2-mercaptoquinoline 在 一水合肼 作用下， 以 乙醇 为溶剂， 以75%的产率得到2-mercaptoquinoline-3-carbaldehyde hydrazone
  参考文献：
  名称：

  Synthesis of Quinoline-Based Thieno-Seleno-Phenylquinazolinones

  摘要：

  The synthesis of quinoline-substituted phenylquinazolinones containing sulfur and selenium is described. These molecules were isolated from a series of reactions of 2-phenyl-4H-3,1-benzoxazin-4-one with 2-chloro, 2-thieno, and 2-selenoquinoline-3-carbaldehyde hydrazones. The structure of the isolated compounds has been elucidated on the basis of IR, 1H NMR, mass spectral, and elemental analysis data.

  DOI：

  10.1080/10426500802176945