2-[2-[4-[9-[4-[2-(2-Prop-2-enoxyethoxy)ethoxy]phenyl]-1,10-phenanthrolin-2-yl]phenoxy]ethoxy]ethanol | 1030607-06-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 2-[2-[4-[9-[4-[2-(2-Prop-2-enoxyethoxy)ethoxy]phenyl]-1,10-phenanthrolin-2-yl]phenoxy]ethoxy]ethanol
• 英文别名: 2-[2-[4-[9-[4-[2-(2-prop-2-enoxyethoxy)ethoxy]phenyl]-1,10-phenanthrolin-2-yl]phenoxy]ethoxy]ethanol
• CAS: 1030607-06-7
• 化学式: C₃₅H₃₆N₂O₆
• 分子量: 580.681
• InChiKey: QSOAVQVFEFLBKP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.2
• 重原子数：
  43
• 可旋转键数：
  17
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.26
• 拓扑面积：
  92.2
• 氢给体数：
  1
• 氢受体数：
  8

反应信息

• 作为反应物：
  描述：

  2-[2-[4-[9-[4-[2-(2-Prop-2-enoxyethoxy)ethoxy]phenyl]-1,10-phenanthrolin-2-yl]phenoxy]ethoxy]ethanol 、 间苯二甲酰氯 在 Proton-Sponge 作用下， 以 二氯甲烷 为溶剂， 以66%的产率得到C₇₈H₇₄N₄O₁₄
  参考文献：
  名称：

  A double ring-closing olefin metathesis approach to [3]catenanes

  摘要：

  A [3]catenane with peripheral olefinic macrocycles was conveniently synthesized via a double ring-closing olefin metathesis. Highlights of this work include the synthesis of a 65-membered macrocycle featuring two phenanthroline ligands, a Cu(1)-templated synthesis of a [3]pseudorotaxane, and the key double ring-closing olefin metathesis to afford the desired [3]catenane in 71% yield. (c) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2008.03.012
• 作为产物：
  描述：

  3-溴丙烯 、 2-{2-[4-(9-{4-[2-(2-Hydroxy-ethoxy)-ethoxy]-phenyl}-[1,10]phenanthrolin-2-yl)-phenoxy]-ethoxy}-ethanol 在 sodium hydride 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 以67%的产率得到2-[2-[4-[9-[4-[2-(2-Prop-2-enoxyethoxy)ethoxy]phenyl]-1,10-phenanthrolin-2-yl]phenoxy]ethoxy]ethanol
  参考文献：
  名称：

  A double ring-closing olefin metathesis approach to [3]catenanes

  摘要：

  A [3]catenane with peripheral olefinic macrocycles was conveniently synthesized via a double ring-closing olefin metathesis. Highlights of this work include the synthesis of a 65-membered macrocycle featuring two phenanthroline ligands, a Cu(1)-templated synthesis of a [3]pseudorotaxane, and the key double ring-closing olefin metathesis to afford the desired [3]catenane in 71% yield. (c) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2008.03.012

文献信息

• A double ring-closing olefin metathesis approach to [3]catenanes
  作者：Manav Gupta、Songsu Kang、Michael F. Mayer

  DOI：10.1016/j.tetlet.2008.03.012

  日期：2008.4

  A [3]catenane with peripheral olefinic macrocycles was conveniently synthesized via a double ring-closing olefin metathesis. Highlights of this work include the synthesis of a 65-membered macrocycle featuring two phenanthroline ligands, a Cu(1)-templated synthesis of a [3]pseudorotaxane, and the key double ring-closing olefin metathesis to afford the desired [3]catenane in 71% yield. (c) 2008 Elsevier Ltd. All rights reserved.