diethyl 2-[[(3aR,4S,7R,7aR)-4-[[(2R,3R,4S,5R,6S)-6-methoxy-3,4,5-tris(phenylmethoxy)oxan-2-yl]methoxy]-2,2-dimethyl-7-phenylmethoxy-4,6,7,7a-tetrahydro-3aH-[1,3]dioxolo[4,5-c]pyridin-5-yl]methylidene]propanedioate | 1011245-18-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: diethyl 2-[[(3aR,4S,7R,7aR)-4-[[(2R,3R,4S,5R,6S)-6-methoxy-3,4,5-tris(phenylmethoxy)oxan-2-yl]methoxy]-2,2-dimethyl-7-phenylmethoxy-4,6,7,7a-tetrahydro-3aH-[1,3]dioxolo[4,5-c]pyridin-5-yl]methylidene]propanedioate
• CAS: 1011245-18-3
• 化学式: C₅₁H₆₁NO₁₃
• 分子量: 896.044
• InChiKey: FQJSDLKCPOGWLW-WTSAEXJUSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.7
• 重原子数：
  65
• 可旋转键数：
  23
• 环数：
  7.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  139
• 氢给体数：
  0
• 氢受体数：
  14

反应信息

• 作为产物：
  描述：

  甲基2,3,4-三-O-苄基-α-D-吡喃葡萄糖苷 、 diethyl 2-[[(3aR,4S,7R,7aR)-4-ethylsulfanyl-2,2-dimethyl-7-phenylmethoxy-4,6,7,7a-tetrahydro-3aH-[1,3]dioxolo[4,5-c]pyridin-5-yl]methylidene]propanedioate 在 DMTST 作用下， 以 乙腈 为溶剂， 反应 2.0h， 以60%的产率得到diethyl 2-[[(3aR,4S,7R,7aR)-4-[[(2R,3R,4S,5R,6S)-6-methoxy-3,4,5-tris(phenylmethoxy)oxan-2-yl]methoxy]-2,2-dimethyl-7-phenylmethoxy-4,6,7,7a-tetrahydro-3aH-[1,3]dioxolo[4,5-c]pyridin-5-yl]methylidene]propanedioate
  参考文献：
  名称：

  Iminosugar thioglycosides as glycosyl donors: a route to disaccharides with an iminosugar moiety

  摘要：

  The immosugar thioglycosides are used as glycosyl donors in glycosidation reactions. Thereby, iminosugar glycosides and disaccharide analogues with an iminosugar moiety are prepared. The yields are high and the method is stereoselective. (C) 2007 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2007.11.160