[(1S,2R,5R,6R,7S,8R,10R)-10-(2-hydroxyacetyl)oxy-1,5-dimethyl-8-propan-2-yl-11-oxatricyclo[6.2.1.02,6]undecan-7-yl] 1-methylnaphthalene-2-carboxylate | 1383567-83-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: [(1S,2R,5R,6R,7S,8R,10R)-10-(2-hydroxyacetyl)oxy-1,5-dimethyl-8-propan-2-yl-11-oxatricyclo[6.2.1.02,6]undecan-7-yl] 1-methylnaphthalene-2-carboxylate
• CAS: 1383567-83-6
• 化学式: C₂₉H₃₆O₆
• 分子量: 480.601
• InChiKey: ZZLPSMDRLTYAJS-GOMFHWHSSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6
• 重原子数：
  35
• 可旋转键数：
  7
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.59
• 拓扑面积：
  82.1
• 氢给体数：
  1
• 氢受体数：
  6

文献信息

• DERIVATIVES OF ENGLERIN FOR THE TREATMENT OF CANCER
  申请人：Christmann Mathias

  公开号：US20140057950A1

  公开（公告）日：2014-02-27

  The present invention relates to compounds of the general formula (I) which show a specific activity against cancer cell lines, the use of these compounds for prophylaxis and treatment of cancer as well as to pharmaceutical compositions containing at least one compound of general formula (I).