| 635316-95-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• CAS: 635316-95-9
• 化学式: C₅₉H₅₆N₂O₁₃
• 分子量: 1001.1
• InChiKey: PNWRCCHVMGSNEY-CHGVDUTOSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.32
• 重原子数：
  74.0
• 可旋转键数：
  21.0
• 环数：
  10.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  168.83
• 氢给体数：
  1.0
• 氢受体数：
  13.0

反应信息

• 作为反应物：
  描述：

  [(4aR,6R,7S,8S,8aR)-7-[(4-methoxyphenyl)methoxy]-6-methylsulfanylspiro[4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxine-2,1'-cyclohexane]-8-yl]oxy-tert-butyl-dimethylsilane 、 在 2,3-二氯-5,6-二氰基-1,4-苯醌 作用下， 以 二氯甲烷 为溶剂， 反应 2.0h， 生成
  参考文献：
  名称：

  Synthesis of an octamannosyled glycan chain, the key oligosaccharide structure in ER-associated degradation

  摘要：

  The high-mannose type decasaccharide (Man(8)GlcNAc(2)) the proposed ligand of ER residing mannosidase-like proteins (MLP), and its monoglycosylated homologue (alpha-Glc(1)Man(8)GlcNAc(2)) were synthesized. The oligosaccharide assembly was performed in a convergent and stereoselective manner, using three oligosaccharide components, a core trisaccharide having a beta-mannoside bond, a liner mannotriose, and a branched mannotetraose. (C) 2003 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/s0008-6215(03)00357-4
• 作为产物：
  描述：

  在 lithium hydroxide 、 双氧水 作用下， 以 四氢呋喃 为溶剂， 反应 2.0h， 生成
  参考文献：
  名称：

  Synthesis of an octamannosyled glycan chain, the key oligosaccharide structure in ER-associated degradation

  摘要：

  The high-mannose type decasaccharide (Man(8)GlcNAc(2)) the proposed ligand of ER residing mannosidase-like proteins (MLP), and its monoglycosylated homologue (alpha-Glc(1)Man(8)GlcNAc(2)) were synthesized. The oligosaccharide assembly was performed in a convergent and stereoselective manner, using three oligosaccharide components, a core trisaccharide having a beta-mannoside bond, a liner mannotriose, and a branched mannotetraose. (C) 2003 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/s0008-6215(03)00357-4